Search
Search Results
-
G protein-coupled estrogen receptor activates PI3K/AKT/mTOR signaling to suppress ferroptosis via SREBP1/SCD1-mediated lipogenesis
BackgroundLung cancer is the leading cause of cancer-related death worldwide. The sex differences in the occurrence and fatality rates of non-small...
-
Efficacy of Bravecto® Plus spot-on solution for cats (280 mg/ml fluralaner and 14 mg/ml moxidectin) in the prevention of feline Aelurostrongylus abstrusus infection evaluated in a multi-diagnostic approach
BackgroundAelurostrongylus abstrusus is one of the most important respiratory nematodes of felines. Infections may lead to respiratory clinical...
-
Clinical characteristics and comorbidities of COVID-19 in unvaccinated patients with Down syndrome: first year report in Brazil
Patients with Down syndrome (DS) are more affected by the Coronavirus Disease (COVID)-19 pandemic when compared with other populations. Therefore,...
-
G-protein coupled estrogen receptor (GPER1) activation promotes synaptic insertion of AMPA receptors and induction of chemical LTP at hippocampal temporoammonic-CA1 synapses
It is well documented that 17β estradiol (E2) regulates excitatory synaptic transmission at hippocampal Shaffer-collateral (SC)-CA1 synapses, via...
-
Echinococcus granulosus (sensu stricto) (G1, G3) and E. ortleppi (G5) in Pakistan: phylogeny, genetic diversity and population structural analysis based on mitochondrial DNA
BackgroundCystic echinococcosis (CE) is a serious tapeworm infection caused by Echinococcus granulosus ( sensu lato ) which infects a wide range of...
-
Dynamics of the Spindle Assembly Checkpoint
The spindle assembly checkpoint (SAC) normally acts to prevent cells that have not fully completed separation of their replicated chromosomes from...
-
CDC6, a key replication licensing factor, is overexpressed and confers poor prognosis in diffuse large B-cell lymphoma
BackgroundCell division cycle 6 (CDC6) is a key licensing factor in the assembly of pre-replicative complexes at origins of replication. The role of...
-
The search for CDK4/6 inhibitor biomarkers has been hampered by inappropriate proliferation assays
CDK4/6 inhibitors are effective at treating advanced HR+ /HER2- breast cancer, however biomarkers that can predict response are urgently needed. We...
-
Toxoplasma gondii infection in goats: serological, pathological, and clinical monitoring during gestation
This study aimed to evaluate Toxoplasma gondii infection in pregnant goats. The goats were divided into two groups: group one (G1) comprised of 31...
-
G1 Premature Chromosome Condensation (PCC) Assay
Premature chromosome condensation (PCC) is a sensitive and unique way to detect interphase chromosome damage and its recovery in mammalian cells...
-
Synovial fluid and radiographic evaluation of joints from dogs with visceral leishmaniasis
BackgroundPolyarthritis has been associated with canine visceral leishmaniasis (CanVL), and co-infection with Ehrlichia canis is common and may...
-
Determination of Versikine Levels by Enzyme-Linked Immunosorbent Assay (ELISA)
The proteoglycan versican plays multiple roles in cancer progression, from promoting cell invasion and proliferation to evasion of immune...
-
Structures of the four Ig-like domain LILRB2 and the four-domain LILRB1 and HLA-G1 complex
Leukocyte immunoglobulin (Ig)-like receptors (LILRs), also known as CD85 and immunoglobulin-like transcripts (ILTs), play pivotal roles in regulating...
-
Update on the genetic diversity and population structure of Echinococcus granulosus in Gansu Province, Tibet Autonomous Region, and **njiang Uygur Autonomous Region, Western China, inferred from mitochondrial cox1, nad1, and nad5 sequences
The identification of additional Echinococcus granulosus sensu lato (s.l.) complex species/genotypes in recent years raises the possibility that...
-
Time–frequency characteristics of the vibrations underlying the first fetal heart sound: a preliminary study
This work studied, for the first time, the time–frequency characteristics of the vibrations underlying the first fetal heart sound (S1). To this end,...
-
The emergence of novel Iranian variants in sheeppox and goatpox viral envelope proteins with remarkably altered putative binding affinities with the host receptor
The outbreak of Sheep and goat pox (SGP) viral infections have increasingly been reported despite vaccinating the majority of sheep populations in...
-
Correction to: MicroRNA-99a induces G1-phase cell cycle arrest and suppresses tumorigenicity in renal cell carcinoma
An amendment to this paper has been published and can be accessed via the original article.
-
Cell Cycle Arrest Biomarkers in the Intensive Care Unit
AKI is a clinical syndrome mainly manifested as a sharp decline in renal function, which is a common complication in the ICU and is characterized by...
-
KNSTRN Is a Prognostic Biomarker That Is Correlated with Immune Infiltration in Breast Cancer and Promotes Cell Cycle and Proliferation
Kinetochore-localized astrin/SPAG5-binding protein (KNSTRN) promotes the progression of bladder cancer and lung adenocarcinoma. However, its...
-
Echinococcus spp. and genotypes infecting humans in Tibet Autonomous Region of China: a molecular investigation with near-complete/complete mitochondrial sequences
BackgroundMolecular markers are essential to identify Echinococcus species and genotypes in areas with multiple Echinococcus species to understand...
