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Effects of prolonged administration of the angiotensin converting enzyme inhibitor CGS 16617 in normotensive volunteers
A new, orally active angiotensin converting enzyme (ACE) inhibitor, CGS 16617, has been evaluated in normotensive subjects during acute and prolonged...
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Modulation of gentamicin nephrotoxicity by chronic inhibition of angiotensin-I-converting enzyme in rat
Perindopril, a new specific and potent inhibitor of angiotensin-I-converting enzyme, was used to evaluate the possible participation of inhibition of...
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Enalapril and hydrochlorothiazide in hypertensive Africans
The antihypertensive efficacy both of angiotensin converting enzyme (ACE) inhibitors and thiazide diuretics has been claimed to be influenced by...
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Pharmacokinetics of Angiotensin Converting Enzyme Inhibitors in Plasma and Tissue Using Radioinhibitor Binding and Displacement Assays
Angiotensin converting enzyme (ACE) inhibitors now have an important place in the treatment of hypertension and congestive cardiac failure1-3. After... -
Safety and tolerance of single oral doses of trandolapril (RU 44.570), a new angiotensin converting enzyme inhibitor
The safety and tolerance of single oral doses of a new angiotensin converting enzyme (ACE) inhibitor, trandolapril have been examined in 90 healthy...
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The haemodynamic and humoral effects of treatment for one month with the angiotensin converting enzyme inhibitor perindopril in salt replete hypertensive patients
We have studied the effects of treatment for one month with perindopril, 4 or 8 mg once daily, in seven hypertensive patients. Blood pressure was...
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Effect on blood pressure and the renin-angiotensin system of repeated doses of the converting enzyme inhibitor CGS 14824A
A new, orally active angiotensin converting enzyme (ACE) inhibitor, CGS 14824A, was evaluated in 12 healthy male volunteers. Two groups each of 6...
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Effects of angiotensin converting enzyme inhibitor, perindopril, on autonomic reflexes
The effect of the angiotensin converting enzyme inhibitor, perindopril, on autonomic function was assessed in a double blind, placebo controlled,...