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A phase II study of weekly cisplatin, 6S-stereoisomer leucovorin and fluorouracil as first-line chemotherapy for elderly patients with advanced gastric cancer
The incidence of gastric cancer (GC) increases significantly after the fifth decade and palliative chemotherapy is the ultimate treatment in the...
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Drugs that target cholinesterases
Currently, cholinesterase inhibitors (ChEI) represent the treatment of choice for Alzheimer’s disease (AD). Following the introduction in the 1980s...
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Identifying factors associated with disability-related differences in breast cancer screening (United States)
Objective : The purpose of this study was to identify factors that could explain breast cancer underutilization among women age 40 and older with...
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Improvement in muscular performance and decrease in tumor necrosis factor level in old age after antioxidant treatment
Aging-related loss of muscle function is a predictor of mortality and a surrogate parameter of the aging process. Its consequences include a high...
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Slowing the progression of cognitive decline in alzheimer’s disease using mifepristone
High circulating levels of glucocorticoid hormones adversely affect cognition. Previous studies exploring the hypothalamic-pituitary-adrenal (HPA)...
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HIV-associated cognitive impairment before and after the advent of combination therapy
The objective of this study was to describe the occurrence of HIV dementia and neuropsychological testing abnormalities in a new cohort of...
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Benzodiazepine use in an elderly community-dwelling population
Objectives : The objective of this study was to describe determinants of current and subsequent benzodiazepine use in an elderly population, the...
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Neuropsychologische testresultaten en rijprestaties bij oudere automobilisten met cognitieve functiestoornissen
Met de vergrijzing van de bevolking neemt het aandeel in het verkeer van automobilisten boven de 70 jaar gestaag toe. Hierdoor zal het aantal...
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Enterococcal Pheromone-Like Activity Derived from a Lipoprotein Signal Peptide Encoded by a Staphylococcus aureus Plasmid
In Enterococcus faecalis, recipient cells secrete hepta- or octapeptide pheromones which induce the expression of conjugative transfer functions in...
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Chronic Fatigue Syndrome in the Elderly
Although there is a firm knowledge base emerging on chronic fatigue syndrome (CFS) in groups of patients who have been scientifically identified and...
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The pAD1 Sex Pheromone Response in Enterococcus faecalis
pAD1 (60 kb) is a hemolysin plasmid that encodes a mating response to the octapeptide sex pheromone cAD1. (The pAD1 system is reviewed in ref. 1.)...
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Alzheimer Disease
The systematic development of Alzheimer Disease (A.D.) therapy is only ten year old. It was initiated on a large scale following the publication in...
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Measurement of upper extremity orientation by video stereometry system
In the attempt to gain a broader understanding of the causal relationships behind work-related symptoms of pain in the human shoulder, monitoring of...
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Different methodological approaches for the construction of a therapy sensitive ADL scale for the assessment of Alzheimer patients
The purpose of this paper was the presentation of the work of the international ADL project which aims to construct a therapy sensitive ADL scale for...
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Rating Scales
A number of evaluations are currently used to measure a wide range of cognitive and other behavioral functions in patients with Alzheimer’s disease...
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Management of the Family
The numbers of demented elderly and their dependency on family and health care systems is a public health concern in most developed countries in the...
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1,1′-Ethylidenebis(tryptophan) (peak E) induces functional activation of human eosinophils and interleukin 5 production from T lymphocytes: Association of eosinophilia-myalgia syndrome with al-tryptophan contaminant
This study was designed to clarify the important association between eosinophilia-myalgia syndrome (EMS) and the l -tryptophan contaminant, “Peak E.”...
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Sex Pheromones and the Plasmid-Encoded Mating Response in Enterococcus faecalis
Plasmid-related conjugation in gram-positive, nonstreptomycete bacteria was first reported in 1974 by Jacob and Hobbs (38). They identified an...
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Klinische Beurteilungsebenen hirnorganischer Psychosyndrome: Zum Problem einer differenzierten Befunderhebung
Die klinische Beurteilung eines Krankheitsbildes und seiner Modifikation unter einer therapeutischen Intervention ist ein synthetischer Akt, der eine...