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Blood DNA methylation signatures of lifestyle exposures: tobacco and alcohol consumption
BackgroundSmoking and alcohol consumption may compromise health by way of epigenetic modifications. Epigenetic signatures of alcohol and tobacco...
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Reductions in smoking due to ratification of the Framework Convention for Tobacco Control in 171 countries
Smoking globally kills over half of long-term smokers and causes about 7 million annual deaths. The World Health Organization Framework Convention...
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Environmental tobacco smoke exposure exaggerates bleomycin-induced collagen overexpression during pulmonary fibrogenesis
Environmental tobacco smoke (ETS) is known to cause lung inflammatory and injurious responses. Smoke exposure is associated with the pathobiology...
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Multimodal 7T imaging reveals enhanced functional coupling between salience and frontoparietal networks in young adult tobacco cigarette smokers
Tobacco cigarette smoking is associated with disrupted brain network dynamics in resting brain networks including the Salience (SN) and Fronto...
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Molecular characterization of a new botybirnavirus that infects Alternaria sp. from tobacco
The genus Alternaria comprises many important fungal pathogens that infect a wide variety of organisms. In this report, we present the discovery of a...
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Effects of educational interventions based on the theory of planned behavior on oral cancer-related knowledge and tobacco smoking in adults: a cluster randomized controlled trial
BackgroundThe theory of planned behavior (TPB) is an effective model for facilitating behavioral change. The aim of the present study was to evaluate...
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Smokeless tobacco and cigarette smoking: chemical mechanisms and cancer prevention
Tobacco products present a deadly combination of nicotine addiction and carcinogen exposure resulting in millions of cancer deaths per year...
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Anti-hyperalgesic and anti-inflammatory effects of 4R-tobacco cembranoid in a mouse model of inflammatory pain
4R is a tobacco cembranoid that binds to and modulates cholinergic receptors and exhibits neuroprotective and anti-inflammatory activity. Given the...
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Tobacco Use Among Dental Students in Morocco: Opportunities for Professional Cancer Education
The study aimed to evaluate tobacco use, attitudes, knowledge, and perceptions about tobacco control policies and smoking cessation counseling among...
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A prospective cohort study on the association between waterpipe tobacco smoking and gastric cancer mortality in Northern Vietnam
Tobacco consumption, as a worldwide problem, is a risk factor for several types of cancer. In Vietnam, tobacco consumption in the form of waterpipe...
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Smokeless tobacco enhances allergic inflammation, aggravation of asthma and oxidative stress in asthmatic patients from Algeria
PurposeDespite their effects on human health, the link between smokeless tobacco (ST) consumption and asthma severity in asthmatic patients is still...
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Sex differences in the tumor promoting effects of tobacco smoke in a cRaf transgenic lung cancer disease model
Tobacco smoke (TS) is the leading cause for lung cancer (LC), and female smokers are at a greater risk for LC. Yet, the underlying causes are...
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The Unequivocal Relationship Between Tuberculosis and Tobacco: Integration of Two Maladies
Tuberculosis (TB) and tobaccoTobacco use are among the leading causes of mortalityMortality and morbidityMorbidity, posing a significant...
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Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing
Most transcriptome-wide association studies (TWASs) so far focus on European ancestry and lack diversity. To overcome this limitation, we aggregated...
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Equitable implementation of lung cancer screening: avoiding its potential to mirror existing inequities among people who use tobacco
PurposeLung cancer is the leading cause of cancer death, but the advent of lung cancer screening using low-dose computed tomography offers a...
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Assessment of the exposure to polycyclic aromatic hydrocarbons in users of various tobacco/nicotine products by suitable urinary biomarkers
Polycyclic aromatic hydrocarbons (PAHs) occur naturally (bitumen and oils) and are formed during all incomplete combustions of organic materials. PAH...
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“We’re always an afterthought”- Designing tobacco control campaigns for dissemination with and to LGBTQ +—serving community organizations: a thematic analysis
PurposeEvidence-based health communication campaigns can support tobacco control and address tobacco-related inequities among lesbian, gay, bisexual,...
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Knockout of a key gene of the nicotine biosynthetic pathway severely affects tobacco growth under field, but not greenhouse conditions
ObjectiveThere is great interest in develo** tobacco plants containing minimal amounts of the addictive compound nicotine. Quinolate...
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Comparative study of the effects of cigarette smoke versus next-generation tobacco and nicotine product extracts on inflammatory biomarkers of human monocytes
Monocytes exhibiting a pro-inflammatory phenotype play a key role in adhesion and development of atherosclerotic plaques. As an alternative to...
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Tobacco smoking associates with NF1 mutations exacerbating survival outcomes in gliomas
Tobacco smoking is associated with increased risks of nearly 20 types of cancer. Although the association between smoking and gliomas, the most...
