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Impact of BMI on the survival outcomes of non-small cell lung cancer patients treated with immune checkpoint inhibitors: a meta-analysis
ObjectivesICIs have become the standard treatment for advanced NSCLC patients. Currently, PD-L1 is the most widely useful biomarker to predict ICI...
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Association of the TRIM family protein with survival outcomes and clinicopathological features in colorectal cancer: a systematic review and meta-analysis
BackgroundThe tripartite motif (TRIM) proteins have been reported to play crucial roles in various malignancies. However, the clinical significance...
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Association of CYP24A1 with survival and drug resistance in clinical cancer patients: a meta-analysis
BackgroundAcquired chemo-drug resistance constantly led to the failure of chemotherapy for malignant cancers, consequently causing cancer relapse....
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Causal roles and clinical utility of cardiovascular proteins in colorectal cancer risk: a multi-modal study integrating mendelian randomization, expression profiling, and survival analysis
PurposeThis comprehensive investigation delved into the intricate causal interplay existing between cardiovascular-related plasma proteins and the...
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Prognostic model on overall survival in elderly nasopharyngeal carcinoma patients: a recursive partitioning analysis identifying pre-treatment risk stratification
BackgroundWe aimed to evaluate the optimal management for elderly patients with nasopharyngeal carcinoma (NPC) with intensity-modulated radiotherapy...
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Pretreatment quality of life and survival in patients with lung cancer: a systematic review and meta-analysis
BackgroundAlthough many studies have explored the correlation between quality of life and survival, none have reported this relationship for specific...
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Circulating myeloid-derived suppressor cells and survival in prostate cancer patients: systematic review and meta-analysis
BackgroundImmunotherapy has not achieved improvement of survival in prostate cancer patients. Myeloid-derived suppressor cells (MDSCs) in tumor...
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Impact of preoperative transcatheter arterial chemoembolization (TACE) on postoperative long-term survival in patients with nonsmall hepatocellular carcinoma: a propensity score matching analysis
BackgroundThe purpose of this propensity score matching (PSM) analysis was to compare the effects of preoperative transcatheter arterial...
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Long-term survival after neoadjuvant therapy for triple-negative breast cancer under different treatment regimens: a systematic review and network meta-analysis
BackgroundTriple-negative breast cancer (TNBC) is a life-threatening subtype of breast cancer with limited treatment options. Therefore, this network...
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Survival benefit and biomarker analysis of pyrotinib or pyrotinib plus capecitabine for patients with HER2-positive metastatic breast cancer: a pooled analysis of two phase I studies
BackgroundPyrotinib, a novel irreversible tyrosine kinase inhibitor (TKI), has demonstrated promising antitumor activity to improve the overall...
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Survival analysis after stereotactic ablative radiotherapy for early stage non-small cell lung cancer: a single-institution cohort study
BackgroundStereotactic ablative radiotherapy (SABR) is the standard treatment for medically inoperable early-stage non-small cell lung cancer...
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Relative efficacy of antibody-drug conjugates and other anti-HER2 treatments on survival in HER2-positive advanced breast cancer: a systematic review and meta-analysis
BackgroundNovel antibody-drug conjugates (ADCs) drugs present a promising anti-cancer treatment, although survival benefits for HER2-positive...
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Ten-year retrospect of the investigation of proximal limbs metastasis in cancer: a multi-center study on survival outcome, limb function status and surgical procedures analysis
BackgroundThe aim of study was to evaluate survival outcome and limb function in cancer patients with proximal limbs metastasis. Associated factors...
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dsSurvival: Privacy preserving survival models for federated individual patient meta-analysis in DataSHIELD
ObjectiveAchieving sufficient statistical power in a survival analysis usually requires large amounts of data from different sites. Sensitivity of...
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Pan-cancer analysis implicates novel insights of lactate metabolism into immunotherapy response prediction and survival prognostication
BackgroundImmunotherapy has emerged as a potent clinical approach for cancer treatment, but only subsets of cancer patients can benefit from it....
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Time-varying associations of patient and tumor characteristics with cancer survival: an analysis of SEER data across 14 cancer sites, 2004–2017
PurposeSurveillance, Epidemiology, and End Results (SEER) cancer registries provides information about survival duration and cause of death for...
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Progression-free survival as a surrogate endpoint for overall survival in patients with relapsed or refractory multiple myeloma
ObjectivesThe goal of the research was to assess the quantitative relationship between median progression-free survival (PFS) and median overall...
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The prognostic role of tumor mutation burden on survival of breast cancer: a systematic review and meta-analysis
BackgroundAs a potential genetic biomarker, tumor mutation burden (TMB) has made progress in numerous tumors. There are limited data regarding TMB...
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Dynamic survival analysis of gastrointestinal stromal tumors (GISTs): a 10-year follow-up based on conditional survival
BackgroundThe prognosis of patients with gastrointestinal stromal tumors (GISTs) is generally evaluated at the time of diagnosis but does not reflect...
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Sarcopenia as a risk factor of progression-free survival in patients with metastases: a systematic review and meta-analysis
BackgroundMetastasis of cancer causes more than 90% of cancer deaths and is severely damaging to human health. In recent years, several studies have...
