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ERN GENTURIS clinical practice guidelines for the diagnosis, treatment, management and surveillance of people with schwannomatosis
A Guideline Group (GG) was convened from multiple specialties and patients to develop the first comprehensive schwannomatosis guideline. The GG...
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Dealing with ambivalence in the practice of advanced genetic healthcare: towards an ethical choreography
The implementation of next-generation sequencing (NGS) in diagnostic practice has stimulated ongoing debates on how to construct and perform “good”...
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Knowledge, attitude and practice of infection prevention and control precautions among laboratory staff: a mixed-methods systematic review
BackgroundClinical laboratories provide diagnostic testing services to support the effective delivery of care in today’s complex healthcare systems....
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Preimplantation genetic testing for aneuploidy: challenges in clinical practice
Preimplantation genetic testing for aneuploidy (PGT-A) has been used widely during in vitro fertilization procedures in assisted reproductive centers...
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Quality evaluation of guidelines for the diagnosis and treatment of radiation enteritis
ObjectiveTo systematically evaluate the guidelines for the diagnosis and treatment of radioactive enteritis, compare their differences and reasons...
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A comprehensive systematic review of colorectal cancer screening clinical practices guidelines and consensus statements
High-quality clinical practice guidelines (CPGs) and consensus statements (CSs) are essential for evidence-based medicine. The purpose of this...
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Alzheimer blood biomarkers: practical guidelines for study design, sample collection, processing, biobanking, measurement and result reporting
Alzheimer’s disease (AD), the most common form of dementia, remains challenging to understand and treat despite decades of research and clinical...
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European Practice for CDI Treatment
Clostridioides difficile infection (CDI) remains a significant cause of morbidity and mortality worldwide. Historically, two antibiotics... -
Expanding ACMG variant classification guidelines into a general framework
BackgroundThe American College of Medical Genetics and Genomics (ACMG)-recommended five variant classification categories (pathogenic, likely...
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The Physical Activity and Cancer Control (PACC) framework: update on the evidence, guidelines, and future research priorities
BackgroundWe proposed the Physical Activity and Cancer Control (PACC) framework in 2007 to help organise, focus, and stimulate research on physical...
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A practice guide on antimicrobial stewardship in nursing homes
A practice guide to help nursing homes set up an antimicrobial stewardship (AMS) program was developed based on experiences gained during a project...
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Best practice guidance for antibiotic audit and feedback interventions in primary care: a modified Delphi study from the Joint Programming Initiative on Antimicrobial resistance: Primary Care Antibiotic Audit and Feedback Network (JPIAMR-PAAN)
BackgroundPrimary care is a critical partner for antimicrobial stewardship efforts given its high human antibiotic usage. Peer comparison audit and...
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Healthcare workers’ compliance with the catheter associated urinary tract infection prevention guidelines: an observational study in Yemen
BackgroundCatheter-associated urinary tract infection is a global problem but it can be prevented with the appropriate implementation of...
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Adherence to national malaria treatment guidelines in private drug outlets: a cross-sectional survey in the malaria-endemic Kisumu County, Kenya
BackgroundMalaria prevalence in Kenya is 6%, with a three-fold higher prevalence in western Kenya. Adherence to malaria treatment guidelines improves...
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Potentially inappropriate medication use in the elderly: physicians’ and hospital pharmacists knowledge, practice, confidence, and barriers
BackgroundInappropriate medication prescribing and dispensing by physicians and pharmacists is a preventable cause of morbidity and mortality in the...
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Consensus reporting guidelines to address gaps in descriptions of ultra-rare genetic conditions
Genome-wide sequencing and genetic matchmaker services are propelling a new era of genotype-driven ascertainment of novel genetic conditions. The...
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Fidelity of implementation of national guidelines on malaria diagnosis for children under-five years in Rivers State, Nigeria
BackgroundMalaria is still a disease of global public health importance and children under-five years of age are the most vulnerable to the disease....
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Predictors of physicians’ intentions to use clinical practice guidelines on antimicrobial in tertiary general hospitals of China: a structural equation modeling approach
BackgroundWith inappropriate use of antimicrobials becoming a great public health concern globally, the issue of applying clinical practice...
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EMQN best practice guidelines for genetic testing in dystrophinopathies
Dystrophinopathies are X-linked diseases, including Duchenne muscular dystrophy and Becker muscular dystrophy, due to DMD gene variants. In recent...