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In vitro and in silico evaluation of some plant extracts and phytocompounds against multidrug-resistant Gram-negative bacteria
The spread of multidrug-resistant Gram-negative (MDR) bacteria is a global public health problem, as infections caused by MDR Gram-negative bacteria...
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Role of miR-24-3p and miR-146a-5p in dendritic cells’ maturation process induced by contact sensitizers
MiRNAs are non-coding RNA molecules that regulate gene expression at the post-transcriptional level. Although allergic contact dermatitis has been...
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Evaluation of cinnamon extract effects on clbB gene expression and biofilm formation in Escherichia coli strains isolated from colon cancer patients
BackgroundColon cancer is one of the most common malignancies and the fourth leading cause of cancer-related mortality in the world. Colibactin,...
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Pioneering Topical Ointment Intervention for Unprecedented Antimicrobial and Diabetic Wound Management with Phenylpropanoids and Nano-Silver
Addressing the intertwined challenges of antimicrobial resistance and impaired wound healing in diabetic patients, an oil/water emulsion-based...
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Cinnamaldehyde ameliorates STZ-induced rat diabetes through modulation of IRS1/PI3K/AKT2 pathway and AGEs/RAGE interaction
Type 2 diabetes mellitus (T2D) is a chronic metabolic disorder considered to be the most predominant form of diabetes throughout the world. This...
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Defining the reactivity of nanoparticles to peptides through direct peptide reactivity assay (DPRA) using a high pressure liquid chromatography system with a diode array detector
The possibility of inducing skin sensitization reactions following exposure to various chemicals can lead to skin diseases, and the evaluation of...
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Cinnamaldehyde exerts vasculoprotective effects in hypercholestrolemic rabbits
The effects of cinnamaldehyde (CIN), a commonly consumed food flavor, against high-cholesterol diet (HCD)-induced vascular damage in rabbits were...
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Spices and Biomarkers of COVID-19: A Mechanistic and Therapeutic Perspective
In the face of the COVID-19 pandemic, many people around the world have increased their healthy behaviors to prevent transmission of the virus and... -
Chemical composition of four essential oils and their adulticidal, repellence, and field oviposition deterrence activities against Culex pipiens L. (Diptera: Culicidae)
Effective mosquito repellents can limit the transmission of vector-borne diseases to humans. Consequently, there is an urgent need to develop...
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Phytomolecules as an Alternative Medicine to Combat Antimicrobial Resistance
Antimicrobials are natural, semisynthetic, or man-made biological molecules that are effective against infectious microorganisms. They play a crucial... -
Phytomolecules as an Alternative Medicine to Combat Antimicrobial Resistance
Antimicrobials are natural, semisynthetic, or man-made biological molecules that are effective against infectious microorganisms. They play a crucial... -
Essential oils and isolated compounds for tick control: advances beyond the laboratory
BackgroundTick control is a worldwide challenge due to its resistance to acaricides. Essential oils (EOs) and isolated compounds (EOCs) are potential...
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Clustering Analysis of Natural D-borneol Resource Plants Based on Simple Sequence Repeat (SSR) Markers, Leaf Morphology, and Chemical Composition
D-borneol is a double-loop monoterpene with a wide use in the pharmaceutical, food, and cosmetics industries. Natural D-borneol can be extracted from...
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The blockade of transient receptor potential ankyrin 1 (TRPA1) protects against PTZ-induced seizure
Treatment of epilepsy remains a major problem as some epileptic patients do not respond to the current therapeutics. Transient receptor potential...
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Therapeutic Potential of Essential Oils against SARS-CoV-2 Infection
Essential oils consist of a complex mixture of diverse, lipophilic and volatile phytochemical constituents associated with a wide range of... -
Assessment of Cinnamon as an Antimicrobial Agent
Due to the lack of awareness and inappropriate use of antibiotics, as well as the ability of bacteria to cross-transmit antibiotic resistance, there... -
Appetite-enhancing effects of inhaling cinnamon, clove, and fennel essential oils containing phenylpropanoid analogues
Cinnamon, clove, and fennel are commonly used as spices and herbal medicines, and one of their medicinal uses is as aromatic stomachics. We...
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Gpr83 Tunes Nociceptor Function, Controlling Pain
The function of peripheral nociceptors is frequently tuned by the action of G protein-coupled receptors (GPRs) that are expressed in them, which...