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Evaluation of Rhododendri Mollis Flos and its representative component as a potential analgesic
Rhododendri Mollis Flos ( R. mole Flos), the dried flowers of Rhododendron mole G. Don, have the ability to relieve pain, dispel wind and dampness,...
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Evaluation of covariate effects using variance-based global sensitivity analysis in pharmacometrics
In pharmacometrics, understanding a covariate effect on an interested outcome is essential for assessing the importance of the covariate....
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Cyclodextrin inclusion complex of a multi-component natural product by hot-melt extrusion
This study aimed to investigate whether hot-melt extrusion (HME) processing can promote molecular encapsulation of a multi-component natural product...
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Paraoxonase 1 status is a major Janus-faced component of mild and moderate acute ischemic stroke and consequent disabilities
Aims: This study aims to examine the associations between paraoxonase 1 (PON)1 status and acute ischemic stroke (AIS) and consequent disabilities....
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Biologically plausible single-layer networks for nonnegative independent component analysis
An important problem in neuroscience is to understand how brains extract relevant signals from mixtures of unknown sources, i.e., perform blind...
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Structure Based Machine Learning Prediction of Retention Times for LC Method Development of Pharmaceuticals
PurposeSignificant resources are spent on develo** robust liquid chromatography (LC) methods with optimum conditions for all project in the...
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Comparison Between Pure Component Modeling Approaches for Monitoring Pharmaceutical Powder Blends with Near-Infrared Spectroscopy in Continuous Manufacturing Schemes
Near-infrared (NIR) spectroscopy has become an important process analytical technology (PAT) for monitoring and implementing control in continuous...
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R2ROC: an efficient method of comparing two or more correlated AUC from out-of-sample prediction using polygenic scores
Polygenic risk scores (PRSs) enable early prediction of disease risk. Evaluating PRS performance for binary traits commonly relies on the area under...
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Novel biphasic mechanism of the canonical Wnt signalling component PYGO2 promotes cardiomyocyte differentiation from hUC-MSCs
Human umbilical cord–derived mesenchymal stem cells (hUC-MSCs) are used to regenerate the myocardium during cardiac repair after myocardial...
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HPLC-Fluorescence Detection Method for Concurrent Estimation of Domperidone and Naproxen. Validation and Eco-Friendliness Appraisal Studies
This work demonstrates a simple and reliable HPLC method with fluorimetric detection for simultaneous estimation of domperidone (DOM) and naproxen...
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Effects of 12-Week Tabata Training on Selected Health-Related Fitness Component in Healthy Untrained Students from Malaysia
PurposeThe study aims to examine the effect of Tabata training on body composition and selected health-related fitness component in healthy untrained...
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Space-time filter for SSVEP brain-computer interface based on the minimum variance distortionless response
Brain-computer interfaces (BCI) based on steady-state visually evoked potentials (SSVEP) have been increasingly used in different applications,...
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Assessing the population’s correct knowledge of malaria in Malaysia: a vital component for malaria elimination certification
BackgroundMalaria remains a public health problem in Malaysia despite a decline in the number of cases in recent years. Public knowledge of malaria...
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Double-sided asymmetric method for automated fetal heart rate baseline calculation
The fetal heart rate (FHR) signal is used to assess the well-being of a fetus during labor. Manual interpretation of the FHR is subject to high...
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Genetic structure of Spirometra mansoni (Cestoda: Diphyllobothriidae) populations in China revealed by a Target SSR-seq method
BackgroundIn China, the plerocercoid of the cestode Spirometra mansoni is the main causative agent of human and animal sparganosis. However, the...
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Application of the relative molar sensitivity method using GC-FID to quantify safranal in saffron (Crocus sativus L.)
Safranal is one flavor component of saffron, which is used as a spice, food additive, and crude drug. In ISO3632, safranal is defined as the compound...
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Glabridin, a bioactive component of licorice, ameliorates diabetic nephropathy by regulating ferroptosis and the VEGF/Akt/ERK pathways
BackgroundGlabridin (Glab) is a bioactive component of licorice that can ameliorate diabetes, but its role in diabetic nephropathy (DN) has seldom...
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Data-driven exploratory method investigation on the effect of dyslexia education at brain connectivity in Turkish children: a preliminary study
Dyslexia is a specific learning disability that is neurobiological in origin and is characterized by reading and/or spelling problems affecting the...
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Lymphocyte–monocyte–neutrophil index: a predictor of severity of coronavirus disease 2019 patients produced by sparse principal component analysis
BackgroundIt is important to recognize the coronavirus disease 2019 (COVID-19) patients in severe conditions from moderate ones, thus more effective...
