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More than causing (epi)genomic instability: emerging physiological implications of transposable element modulation
Transposable elements (TEs) initially attracted attention because they comprise a major portion of the genomic sequences in plants and animals. TEs...
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The sixth Japanese meeting on biological function and evolution through interactions between hosts and transposable elements
The sixth Japanese meeting on host–transposon interactions, titled “Biological Function and Evolution through Interactions between Hosts and...
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Transposable element subfamily annotation has a reproducibility problem
BackgroundTransposable element (TE) sequences are classified into families based on the reconstructed history of replication, and into subfamilies...
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Transposable element-derived sequences in vertebrate development
Transposable elements (TEs) are major components of all vertebrate genomes that can cause deleterious insertions and genomic instability. However,...
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T3E: a tool for characterising the epigenetic profile of transposable elements using ChIP-seq data
BackgroundDespite the advent of Chromatin Immunoprecipitation Sequencing (ChIP-seq) having revolutionised our understanding of the mammalian genome’s...
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Pan-cancer analysis identifies tumor-specific antigens derived from transposable elements
Cryptic promoters within transposable elements (TEs) can be transcriptionally reactivated in tumors to create new TE-chimeric transcripts, which can...
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Measuring and interpreting transposable element expression
Transposable elements (TEs) are insertional mutagens that contribute greatly to the plasticity of eukaryotic genomes, influencing the evolution and...
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Characterization of transposable elements within the Bemisia tabaci species complex
BackgroundWhiteflies are agricultural pests that cause negative impacts globally to crop yields resulting at times in severe economic losses and food...
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Transcriptional dynamics of transposable elements in the type I IFN response in Myotis lucifugus cells
BackgroundBats are a major reservoir of zoonotic viruses, and there has been growing interest in characterizing bat-specific features of innate...
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A study of transposable element-associated structural variations (TASVs) using a de novo-assembled Korean genome
Advances in next-generation sequencing (NGS) technology have made personal genome sequencing possible, and indeed, many individual human genomes have...
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A beginner’s guide to manual curation of transposable elements
BackgroundIn the study of transposable elements (TEs), the generation of a high confidence set of consensus sequences that represent the diversity of...
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The fifth Japanese meeting on biological function and evolution through interactions between hosts and transposable elements
The fifth Japanese meeting on host–transposon interactions, titled “Biological Function and Evolution through Interactions between Hosts and...
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TE Hub: A community-oriented space for sharing and connecting tools, data, resources, and methods for transposable element annotation
Transposable elements (TEs) play powerful and varied evolutionary and functional roles, and are widespread in most eukaryotic genomes. Research into...
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Transposable elements shape the evolution of mammalian development
Transposable elements (TEs) promote genetic innovation but also threaten genome stability. Despite multiple layers of host defence, TEs actively...
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Transposable element abundance correlates with mode of transmission in microsporidian parasites
The extreme genome reduction and physiological simplicity of some microsporidia has been attributed to their intracellular, obligate parasitic...
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TE Density: a tool to investigate the biology of transposable elements
BackgroundTransposable elements (TEs) are powerful creators of genotypic and phenotypic diversity due to their inherent mutagenic capabilities and in...
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Comparative genomic and transcriptomic analyses of transposable elements in polychaetous annelids highlight LTR retrotransposon diversity and evolution
BackgroundWith the expansion of high throughput sequencing, we now have access to a larger number of genome-wide studies analyzing the Transposable...
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Investigating mobile element variations by statistical genetics
The integration of structural variations (SVs) in statistical genetics provides an opportunity to understand the genetic factors influencing complex...
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Twenty years of transposable element analysis in the Arabidopsis thaliana genome
Transposable elements (TEs) are mobile repetitive DNA sequences shown to be major drivers of genome evolution. As the first plant to have its genome...
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De Novo Somatic Mosaicism of CYBB Caused by Intronic LINE-1 Element Insertion Resulting in Chronic Granulomatous Disease
Chronic granulomatosis disease (CGD) is a rare inborn error of immunity, characterized by phagocytic respiratory outbreak dysfunction. Mutations...
