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Deep learning radiomics based prediction of axillary lymph node metastasis in breast cancer
This study aimed to develop and validate a deep learning radiomics nomogram (DLRN) for the preoperative evaluation of axillary lymph node (ALN)...
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Optimization of supraclavicular lymph node clinical target volume delineation in high-risk breast cancer: a single center experience and recommendation
BackgroundProphylactic irradiation of supraclavicular lymph node drainage areas can improve the regional control rate of lymph node-positive or lymph...
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Genetic Alterations and Microbial Dysbiosis Underlie Lymph Node Metastasis in Tongue Cancer
Oral cancer presents a significant clinical challenge due to the presence of hidden lymph node metastases, which greatly influence treatment... -
Ultrasonography and clinicopathological features of breast cancer in predicting axillary lymph node metastases
BackgroundEarly identification of axillary lymph node metastasis (ALNM) in breast cancer (BC) is still a clinical difficulty. There is still no good...
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Diagnostic value of applying preoperative breast ultrasound and clinicopathologic features to predict axillary lymph node burden in early invasive breast cancer: a study of 1247 patients
BackgroundSince the Z0011 trial, the assessment of axillary lymph node status has been redirected from the previous assessment of the occurrence of...
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Prediction of the axillary lymph-node metastatic burden of breast cancer by 18F-FDG PET/CT-based radiomics
BackgroundThe axillary lymph-node metastatic burden is closely associated with treatment decisions and prognosis in breast cancer patients. This...
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Noninvasive prediction of axillary lymph node breast cancer metastasis using morphometric analysis of nodal tumor microvessels in a contrast-free ultrasound approach
PurposeChanges in microcirculation of axillary lymph nodes (ALNs) may indicate metastasis. Reliable noninvasive imaging technique to quantify such...
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The lymphatic system and sentinel lymph nodes: conduit for cancer metastasis
The lymphatic system is a complicated system consisting of the lymphatic vessels and lymph nodes draining the extracellular fluid containing cellular...
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Detection of melanoma, breast cancer and head and neck squamous cell cancer sentinel lymph nodes by Tc-99m Tilmanocept (Lymphoseek®)
Technetium-99m-labeled Tilmanocept or Lymphoseek® (Cardinal Health, Dublin, Ohio) is a soluble, synthetic molecule with a small diameter (7 nm),...
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No axillary surgical treatment for lymph node-negative patients after ultra-sonography [NAUTILUS]: protocol of a prospective randomized clinical trial
BackgroundFollowing sentinel lymph node biopsy (SLNB), the axillary recurrence rate is very low although SLNB has a false-negative rate of 5–10%. In...
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Clinical relevance of biomarker discordance between primary breast cancers and synchronous axillary lymph node metastases
Clinical decision-making for patients with breast cancer (BC) is still primarily based on biomarker characteristics of the primary tumor, together...
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Sentinel node involvement with or without completion axillary lymph node dissection: treatment and pathologic results of randomized SERC trial
Based on results of clinical trials, completion ALND (cALND) is frequently not performed for patients with breast conservation therapy and one or two...
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Genetic Alterations and Microbial Dysbiosis Underlie Lymph Node Metastasis in Tongue Cancer
Oral cancer presents a significant clinical challenge due to the presence of hidden lymph node metastases, which greatly influence treatment... -
Metabolic syndrome score as an indicator in a predictive nomogram for lymph node metastasis in endometrial cancer
BackgroundLymph node metastasis (LNM) is an important factor affecting endometrial cancer (EC) prognosis. Current controversy exists as to how to...
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Interrogating the roles of lymph node metastasis in systemic immune surveillance
Lymph nodes (LNs) are principal orchestrators of the adaptive immune response, yet in the context of malignancy, they are typically the first sites...
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Phase III study of HR-positive/HER2-negative/lymph node-positive breast cancer non-responsive to primary chemotherapy: a randomized trial
There are few studies focus on post-neoadjuvant treatment in hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative...
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Application of CT and MRI images based on an artificial intelligence algorithm for predicting lymph node metastasis in breast cancer patients: a meta-analysis
BackgroundThis study aimed to comprehensively evaluate the accuracy and effect of computed tomography (CT) and magnetic resonance imaging (MRI) based...
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Lymph Node Dissection for Papillary Thyroid Carcinoma
Cervical lymph node metastasis is frequent in patients with papillary thyroid carcinoma. In addition to the extent of thyroidectomy, the need as well... -
Noninvasive prediction of axillary lymph node status in breast cancer using promoter profiling of circulating cell-free DNA
BackgroundLymph node metastasis (LNM) is one of the most important factors affecting the prognosis of breast cancer. The accurate evaluation of lymph...
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Noninvasive prediction of node-positive breast cancer response to presurgical neoadjuvant chemotherapy therapy based on machine learning of axillary lymph node ultrasound
ObjectivesTo explore an optimal model to predict the response of patients with axillary lymph node (ALN) positive breast cancer to neoadjuvant...