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  1. Current Treatment Approaches to Breast Cancer

    Breast cancer is a familiar malignancy and the major reason for cancer mortality among females worldwide. Research on breast carcinoma has led to...
    Manzoor Ahmad Mir, Abrar Yousuf Mir in Therapeutic potential of Cell Cycle Kinases in Breast Cancer
    Chapter 2023
  2. How does weight gain since the age of 18 years affect breast cancer risk in later life? A meta-analysis

    Early life factors are important risk factors for breast cancer. The association between weight gain after age 18 and breast cancer risk is...

    Yunan Han, Ebunoluwa E. Otegbeye, ... Adetunji T. Toriola in Breast Cancer Research
    Article Open access 07 March 2024
  3. Effect of metformin as an adjuvant therapy to letrozole on estradiol and other biomarkers involved in the pathogenesis of breast cancer in overweight and obese postmenopausal women: a pilot study

    Introduction

    Metformin may provide a therapeutic benefit in different types of malignancy.

    Purpose

    We aimed at evaluating the effect of metformin as...

    Aya Ahmed El-attar, Osama Mohamed Ibrahim, ... Tarek Mohamed Mostafa in European Journal of Clinical Pharmacology
    Article Open access 23 December 2022
  4. Epidemiology and Risk Factors of Breast Cancer

    The epithelial glandular tissue forms a major part of the breast cancer origin followed by lobular glandular tissue. The initial growth of the tumor...
    Tabassum Zafar, Ab Qayoom Naik, ... Vinoy K. Shrivastava in Breast Cancer: From Bench to Personalized Medicine
    Chapter 2022
  5. Diagnostic-Prognostic Biomarkers and Their Clinical Implication in Breast Cancer

    Breast cancer (BC) is a complex disease that continues to affect global cancer fatalities with its high incidence rate. Hence, BC requires...
    Muskan Budhwar, Madhu Sharma, ... Mani Chopra in Handbook of Oncobiology: From Basic to Clinical Sciences
    Reference work entry 2024
  6. Breast Cancer: Epidemiology, Types, Diagnosis, and Treatment

    Breast cancer is a complex disease, and many aspects of this disease are under intensive research. Better treatment of breast cancer can only be...
    Madhumita Roy, Jaydip Biswas, Amitava Datta in Genetics and Epigenetics of Breast Cancer
    Chapter 2023
  7. Updated overall survival from the MONALEESA-3 trial in postmenopausal women with HR+/HER2− advanced breast cancer receiving first-line ribociclib plus fulvestrant

    Background

    The phase III MONALEESA-3 trial included first- (1L) and second-line (2L) patients and demonstrated a significant overall survival (OS)...

    P. Neven, P. A. Fasching, ... D. J. Slamon in Breast Cancer Research
    Article Open access 31 August 2023
  8. Microcalcifications, mammographic breast density, and risk of breast cancer: a cohort study

    Background

    Breast density and microcalcifications are strongly associated with the risk of breast cancer. However, few studies have evaluated the...

    Soyeoun Kim, Thi Xuan Mai Tran, ... Boyoung Park in Breast Cancer Research
    Article Open access 21 December 2022
  9. Ambient polycyclic aromatic hydrocarbon exposure and breast cancer risk in a population-based Canadian case–control study

    Purpose

    Polycyclic aromatic hydrocarbons (PAHs) represent a class of ubiquitous pollutants recognized as established human carcinogens and...

    Patrick Hinton, Paul J. Villeneuve, ... Will D. King in Cancer Causes & Control
    Article Open access 17 April 2024
  10. Association of area- and volumetric-mammographic density and breast cancer risk in women of Asian descent: a case control study

    Background

    Mammographic density (MD) has been shown to be a strong and independent risk factor for breast cancer in women of European and Asian...

    Shivaani Mariapun, Weang-Kee Ho, ... Soo-Hwang Teo in Breast Cancer Research
    Article Open access 15 May 2024
  11. Dose response relationship between breast cancer and somatotypes during childhood: a systematic review and meta-analysis

    Objectives

    This study aims to evaluate the relationship between breast cancer and somatotypes during early life by meta-analysis and give the...

    Yuqi Dou, Botian Chen, ... Defu Ma in British Journal of Cancer
    Article 07 August 2023
  12. Current status and challenges of breast cancer prevention~DNA methylation would lead to groundbreaking progress in breast cancer prevention~

    The number of breast cancer patients is increasing worldwide. Furthermore, breast cancer often develops in young people, even those only in their...

    Takahiro Tsukioki, Seema A. Khan, Tadahiko Shien in Genes and Environment
    Article Open access 12 December 2023
  13. Temporal changes in mammographic breast density and breast cancer risk among women with benign breast disease

    Introduction

    Benign breast disease (BBD) and high mammographic breast density (MBD) are prevalent and independent risk factors for invasive breast...

    Maeve Mullooly, Shaoqi Fan, ... Gretchen L. Gierach in Breast Cancer Research
    Article Open access 26 March 2024
  14. mTOR inhibition abrogates human mammary stem cells and early breast cancer progression markers

    Background

    Mammary physiology is distinguished in containing adult stem/progenitor cells that are actively amending the breast tissue throughout the...

    Hakim Bouamar, Larry Esteban Broome, ... Lu-Zhe Sun in Breast Cancer Research
    Article Open access 30 October 2023
  15. Associations of established breast cancer risk factors with urinary estrogens in postmenopausal women

    Purpose

    Circulating estrogens are an established risk factor for postmenopausal breast cancer (BCa). We describe the distribution of urinary...

    Lusine Yaghjyan, Lancia N. F. Darville, ... Kathleen M. Egan in Cancer Causes & Control
    Article 06 January 2022
  16. A polygenic score associated with fracture risk in breast cancer patients treated with aromatase inhibitors

    Identifying women at high risk of osteoporotic fracture from aromatase inhibitor (AI) therapy for breast cancer is largely based on known risk...

    Christine Hook, Udit Chatterjee, ... Song Yao in npj Breast Cancer
    Article Open access 20 January 2024
  17. Breast cancer risk factors and mammographic density among 12518 average-risk women in rural China

    Background

    Mammographic density (MD) is a strong risk factor for breast cancer. We aimed to evaluate the association between MD and breast cancer...

    Huijiao Yan, Wenhui Ren, ... Youlin Qiao in BMC Cancer
    Article Open access 09 October 2023
  18. CDk Inhibitor for Treatment of Breast Cancer

    A complicated interaction of Cyclins and cyclin-dependent kinases (CDKs) drives the mammalian cell cycle and one of the main causes or hallmarks of...
    Manzoor Ahmad Mir, Aabida Gul, ... M. Sultan Khan in Therapeutic potential of Cell Cycle Kinases in Breast Cancer
    Chapter 2023
  19. Sleep duration and mortality among breast cancer survivors in the Western New York Exposures and Breast Cancer (WEB) Study

    Purpose

    There is increasing evidence that sleep duration may affect breast cancer survival through effects on circadian function, influencing disease...

    Nisha M. Nair, Caila B. Vaughn, ... Jo L. Freudenheim in Cancer Causes & Control
    Article 18 August 2023
  20. Lipid Nanocarriers for Breast Cancer Treatment

    Excluding non-melanoma skin cancer, breast cancer is considered the most prevalent type of cancer among women. In addition to surgery, radiation...
    Luciana B. Lopes, Alexsandra C. Apolinário, ... Julia S. Passos in Cancer Nanotechnology
    Chapter 2023
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