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Current Treatment Approaches to Breast Cancer
Breast cancer is a familiar malignancy and the major reason for cancer mortality among females worldwide. Research on breast carcinoma has led to... -
How does weight gain since the age of 18 years affect breast cancer risk in later life? A meta-analysis
Early life factors are important risk factors for breast cancer. The association between weight gain after age 18 and breast cancer risk is...
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Effect of metformin as an adjuvant therapy to letrozole on estradiol and other biomarkers involved in the pathogenesis of breast cancer in overweight and obese postmenopausal women: a pilot study
IntroductionMetformin may provide a therapeutic benefit in different types of malignancy.
PurposeWe aimed at evaluating the effect of metformin as...
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Epidemiology and Risk Factors of Breast Cancer
The epithelial glandular tissue forms a major part of the breast cancer origin followed by lobular glandular tissue. The initial growth of the tumor... -
Diagnostic-Prognostic Biomarkers and Their Clinical Implication in Breast Cancer
Breast cancer (BC) is a complex disease that continues to affect global cancer fatalities with its high incidence rate. Hence, BC requires... -
Breast Cancer: Epidemiology, Types, Diagnosis, and Treatment
Breast cancer is a complex disease, and many aspects of this disease are under intensive research. Better treatment of breast cancer can only be... -
Updated overall survival from the MONALEESA-3 trial in postmenopausal women with HR+/HER2− advanced breast cancer receiving first-line ribociclib plus fulvestrant
BackgroundThe phase III MONALEESA-3 trial included first- (1L) and second-line (2L) patients and demonstrated a significant overall survival (OS)...
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Microcalcifications, mammographic breast density, and risk of breast cancer: a cohort study
BackgroundBreast density and microcalcifications are strongly associated with the risk of breast cancer. However, few studies have evaluated the...
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Ambient polycyclic aromatic hydrocarbon exposure and breast cancer risk in a population-based Canadian case–control study
PurposePolycyclic aromatic hydrocarbons (PAHs) represent a class of ubiquitous pollutants recognized as established human carcinogens and...
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Association of area- and volumetric-mammographic density and breast cancer risk in women of Asian descent: a case control study
BackgroundMammographic density (MD) has been shown to be a strong and independent risk factor for breast cancer in women of European and Asian...
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Dose response relationship between breast cancer and somatotypes during childhood: a systematic review and meta-analysis
ObjectivesThis study aims to evaluate the relationship between breast cancer and somatotypes during early life by meta-analysis and give the...
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Current status and challenges of breast cancer prevention~DNA methylation would lead to groundbreaking progress in breast cancer prevention~
The number of breast cancer patients is increasing worldwide. Furthermore, breast cancer often develops in young people, even those only in their...
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Temporal changes in mammographic breast density and breast cancer risk among women with benign breast disease
IntroductionBenign breast disease (BBD) and high mammographic breast density (MBD) are prevalent and independent risk factors for invasive breast...
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mTOR inhibition abrogates human mammary stem cells and early breast cancer progression markers
BackgroundMammary physiology is distinguished in containing adult stem/progenitor cells that are actively amending the breast tissue throughout the...
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Associations of established breast cancer risk factors with urinary estrogens in postmenopausal women
PurposeCirculating estrogens are an established risk factor for postmenopausal breast cancer (BCa). We describe the distribution of urinary...
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A polygenic score associated with fracture risk in breast cancer patients treated with aromatase inhibitors
Identifying women at high risk of osteoporotic fracture from aromatase inhibitor (AI) therapy for breast cancer is largely based on known risk...
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Breast cancer risk factors and mammographic density among 12518 average-risk women in rural China
BackgroundMammographic density (MD) is a strong risk factor for breast cancer. We aimed to evaluate the association between MD and breast cancer...
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CDk Inhibitor for Treatment of Breast Cancer
A complicated interaction of Cyclins and cyclin-dependent kinases (CDKs) drives the mammalian cell cycle and one of the main causes or hallmarks of... -
Sleep duration and mortality among breast cancer survivors in the Western New York Exposures and Breast Cancer (WEB) Study
PurposeThere is increasing evidence that sleep duration may affect breast cancer survival through effects on circadian function, influencing disease...
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Lipid Nanocarriers for Breast Cancer Treatment
Excluding non-melanoma skin cancer, breast cancer is considered the most prevalent type of cancer among women. In addition to surgery, radiation...