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Cancer-derived exosomes as novel biomarkers in metastatic gastrointestinal cancer
Gastrointestinal cancer (GIC) is the most prevalent and highly metastatic malignant tumor and has a significant impact on mortality rates....
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Exploring the potential of microRNA as a diagnostic tool for gestational diabetes
MicroRNAs (miRNAs) are small non-coding RNAs that play critical roles in regulating host gene expression. Recent studies have indicated a role of...
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Non-coding RNAs as potential therapeutic targets for receptor tyrosine kinase signaling in solid tumors: current status and future directions
This review article presents an in-depth analysis of the current state of research on receptor tyrosine kinase regulatory non-coding RNAs (RTK-RNAs)...
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The Role of Liquid Biopsy in Brain Tumors
Current methods of diagnosis and longitudinal monitoring of brain tumors stand to be supplemented and improved by liquid biopsy. Liquid biopsy is the... -
Nanocarrier-Mediated Delivery of MicroRNAs for Fibrotic Diseases
MicroRNAs (miRNAs) are endogenous noncoding RNAs that mediate the fibrotic process by regulating multiple targets. MicroRNA-based therapy can restore...
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Age-dependent alteration of microRNAs related to brain cancer in C6 glioma cells and young and old hippocampal rats after exposure to 1,2-Diacetylbenzene
Objective1,2-Diacetylbenzene (DAB) induces cognitive and motor deficits, which are the most common symptoms of cancer (e.g., glioma), and gene...
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MicroRNAs as a Tool for Differential Diagnosis of Neuromuscular Disorders
Neuromuscular disorders (NMD) are a class of progressive disorders that are characterized by wasting of the muscles. Some of the disorders like...
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Functions and targets of miRNAs in pharmacological and toxicological effects of major components of Tripterygium wilfordii Hook F
Tripterygium wilfordii Hook F (TwHF) has a long history of use as a traditional Chinese medicine and has been widely administered to treat various...
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Regulatory Potential of Noncoding RNAs Co-Located with Cardiomyopathy Related Genes
AbstractNoncoding RNAs (ncRNAs) play an important regulatory role in the activity of genes essential for the development and functioning of...
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Epigallocatechin-3-gallate and cancer: focus on the role of microRNAs
MicroRNAs (miRNAs) are a group of small non-coding RNAs that affect gene expression. The role of miRNAs in different types of cancers has been...
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Deep Learning of miRNAs for Therapeutic Applications
The RNA Precious Medical Initiative requires a safe, affordable, and sustainable device as an administration tool. Why do microRNA (miRNA) quantum... -
Considering Context-Specific microRNAs in Ischemic Stroke with Three “W”: Where, When, and What
MicroRNAs are short non-coding RNA molecules that function as critical regulators of various biological processes through negative regulation of gene...
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Liquid Biopsy in Coronary Heart Disease
Cardiovascular disease (CVD) remains the major cause of morbidity and mortality globally. Accumulating evidence indicates that coronary heart disease... -
Extracellular Vesicles as Biomarkers for Cancer
Because of the minimally invasive nature of biofluid collection, extracellular vesicles (EVs) have promising applications in the diagnosis,... -
Promising roles of non-exosomal and exosomal non-coding RNAs in the regulatory mechanism and as diagnostic biomarkers in myocardial infarction
Non-exosomal non-coding RNAs (non-exo-ncRNAs) and exosomal ncRNAs (exo-ncRNAs) have been associated with the pathological development of myocardial...
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MicroRNAs Function in Dental Stem Cells as a Promising Biomarker and Therapeutic Target for Dental Diseases
Undifferentiated, highly proliferative, clonogenic, and self-renewing dental stem cells have paved the way for novel approaches to mending cleft...
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Crosstalk between long noncoding RNA and microRNA in Cancer
miRNAs and lncRNAs play a central role in cancer-associated gene regulations. The dysregulated expression of lncRNAs has been reported as a hallmark...
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Differential serum microRNAs in premotor LRRK2 G2019S carriers from Parkinson’s disease
The LRRK2 G2019S pathogenic mutation causes LRRK2-associated Parkinson’s disease (L2PD) with incomplete penetrance. LRRK2 non-manifesting carriers...
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Vital METS/MIRAI
Dysregulation of microRNAs (miRNAs) has been implicated in human disease. Further, a panel of vital circulating microRNA has also been involved in... -
The emerging role of MicroRNA-182 in tumorigenesis; a promising therapeutic target
A wide range of studies have indicated that microRNAs (miRNAs), a type of small single-stranded regulatory RNAs, are dysregulated in a different...