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The interactions between PML nuclear bodies and small and medium size DNA viruses
Promyelocytic leukemia nuclear bodies (PM NBs), often referred to as membraneless organelles, are dynamic macromolecular protein complexes composed...
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Evaluation of Viral Recovery Methodologies from Solid Waste Landfill Leachate
Leachate from solid waste landfill is a dark liquid of variable composition and possible source of contamination of groundwater and surface waters....
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Comet Assay for the Detection of Single and Double-Strand DNA Breaks
DNA damage is a common event that occurs during the life span of the majority of cells, as a result of aberrant energy metabolism, exposure to...
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Tau-protein concentrations are not elevated in cerebrospinal fluid of patients with progressive multifocal leukoencephalopathy
Progressive multifocal leukoencephalopathy (PML), caused by infection with John Cunningham polyoma virus (JCPyV) in immune-compromised patients, is a...
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Polyomaviruses shedding in stool of patients with hematological disorders: detection analysis and study of the non-coding control region’s genetic variability
Fragmented data are available on the human polyomaviruses (HPyVs) prevalence in the gastrointestinal tract. Rearrangements in the non-coding control...
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Virological Characterization of Roof-Harvested Rainwater of Densely Urbanized Low-Income Region
Roof-harvested rainwater (RHRW) is considered relatively clean water, even though the possible presence of pathogens in the water may pose human...
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JCPyV microRNA in plasma inversely correlates with JCPyV seropositivity among long-term natalizumab-treated relapsing-remitting multiple sclerosis patients
Sensitive biomarkers are needed to better manage multiple sclerosis (MS) patients for natalizumab (NTZ)-associated risk of progressive multifocal...
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Identification of a novel polyomavirus in wild Sonoran Desert rodents of the family Heteromyidae
Rodents are the largest and most diverse group of mammals. Covering a wide range of structural and functional adaptations, rodents successfully...
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HPyV6 and HPyV7 in urine from immunocompromised patients
BackgroundHuman polyomavirus 6 (HPyV6) and HPyV7 are two of the novel polyomaviruses that were originally detected in non-diseased skin. Serological...
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Gene therapy for castration-resistant prostate cancer cells using JC polyomavirus-like particles packaged with a PSA promoter driven-suicide gene
Prostate cancer is the second most common cancer in men globally. Prostate cancer patients at advanced stages are usually treated with androgen...
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Association between oncogenic human papillomavirus type 16 and Killian polyp
BackgroundKillian polyp (KP) is a benign lesion that arises from the maxillary sinus. The etiology of KP is unknown. The aim of this study was to...
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Herpesviruses, polyomaviruses, parvoviruses, papillomaviruses, and anelloviruses in vestibular schwannoma
Etiology of vestibular schwannoma (VS) is unknown. Viruses can infect and reside in neural tissues for decades, and new viruses with unknown...
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Unmasking viral sequences by metagenomic next-generation sequencing in adult human blood samples during steroid-refractory/dependent graft-versus-host disease
BackgroundViral infections are common complications following allogeneic hematopoietic stem cell transplantation (allo-HSCT). Allo-HSCT recipients...
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Emerging role of human polyomaviruses 6 and 7 in human cancers
BackgroundCurrently 12 human polyomaviruses (HPyVs) have been identified, 6 of which have been associated with human diseases, including cancer. The...
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Detection of Human polyomavirus 2 (HPyV2) in oyster samples in northern Brazil
BackgroundHuman polyomavirus 2 (HPyV2 or JCPyV) is persistent in the environment due to its excretion in urine and feces; it is detected in samples...
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Ubiquitous Merkel Cell Polyomavirus: Causative Agent of the Rare Merkel Cell Carcinoma
Merkel Cell polyomavirus (MCPyV) isMerkel Cell polyomavirus (MCPyV) the only member of the Polyomaviridae family that is directly linked to a type of...
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BK polyomavirus infection promotes growth and aggressiveness in bladder cancer
BackgroundRecent studies have confirmed the integration of the BK polyomavirus (BKPyV) gene into the cellular genome of urothelial carcinomas in...
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Of Predators and Prey
This chapter examines selected viral diseases that illustrate distinct mechanisms of viral spread and infection outcomes. Influenza (acute disease),...
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Viren mit doppelsträngigem DNA-Genom
Es sind viele Viren mit einem doppelsträngigen DNA-Genom bekannt, die Wirbeltiere infizieren. Die Menschen und Säugetiere infizierenden Viren werden...
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SV40 – An Obscure Monkey Virus and the Golden Age of Molecular Biology
The extensive poliovirus vaccination programs of the late 1950s and early 1960s lead to the accidental infection of millions of individuals with an...