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Autonomous learning of nonlocal stochastic neuron dynamics
Neuronal dynamics is driven by externally imposed or internally generated random excitations/noise, and is often described by systems of random or...
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Neuron-Microglia Interaction is Involved in Anti-inflammatory Response by Vagus Nerve Stimulation in the Prefrontal Cortex of Rats Injected with Polyinosinic:Polycytidylic Acid
Injection of polyinosinic:polycytidylic acid (poly(I:C)) into experimental animals induces neuroimmunological responses and thus has been used for...
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The steady state and response to a periodic stimulation of the firing rate for a theta neuron with correlated noise
The stochastic activity of neurons is caused by various sources of correlated fluctuations and can be described in terms of simplified, yet...
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Emergence of stochastic resonance in a two-compartment hippocampal pyramidal neuron model
In vitro studies have shown that hippocampal pyramidal neurons employ a mechanism similar to stochastic resonance (SR) to enhance the detection and...
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Upregulation of Ca2+-binding proteins contributes to VTA dopamine neuron survival in the early phases of Alzheimer’s disease in Tg2576 mice
BackgroundRecent clinical and experimental studies have highlighted the involvement of Ventral Tegmental Area (VTA) dopamine (DA) neurons for the...
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MAP4Ks inhibition promotes retinal neuron regeneration from Müller glia in adult mice
Mammalian Müller glia (MG) possess limited regenerative capacities. However, the intrinsic capacity of mammalian MG to transdifferentiate to generate...
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Glutamate-Based Treatment for Amyotrophic Lateral Sclerosis/Motor Neuron Disease
Glutamate is the most diffused amino acid in the brain throughout the human lifespan, since it is a unique actor in neuronal growth and... -
Multi-scale modeling to investigate the effects of transcranial magnetic stimulation on morphologically-realistic neuron with depression
Transcranial magnetic stimulation (TMS) is a non-invasive neuromodulation technique to activate or inhibit the activity of neurons, and thereby...
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The “One Neuron–One Receptor” Rule in the Physiology and Genetics of Olfaction
The phenomenal sensitivity of the olfactory system and its ability to detect an enormous diversity of olfactory stimuli are to a large extent due to...
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Control of noise-induced coherent oscillations in three-neuron motifs
The phenomenon of self-induced stochastic resonance (SISR) requires a nontrivial scaling limit between the deterministic and the stochastic...
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Modeling idiopathic autism in forebrain organoids reveals an imbalance of excitatory cortical neuron subtypes during early neurogenesis
Idiopathic autism spectrum disorder (ASD) is highly heterogeneous, and it remains unclear how convergent biological processes in affected individuals...
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Spectral resonance in Fitzhugh–Nagumo neuron system: relation with stochastic resonance and its role in EMG signal characterization
This paper examines the existence of spectral resonance in the Fitzhugh–Nagumo (FHN) system driven by periodical signal and unbounded noise having...
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Dynamics of ram** bursts in a respiratory neuron model
Intensive computational and theoretical work has led to the development of multiple mathematical models for bursting in respiratory neurons in the...
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Effects of Kv1.3 knockout on pyramidal neuron excitability and synaptic plasticity in piriform cortex of mice
Kv1.3 belongs to the voltage-gated potassium (Kv) channel family, which is widely expressed in the central nervous system and associated with a...
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Loss of G9a does not phenocopy the requirement for Prdm12 in the development of the nociceptive neuron lineage
Prdm12 is an epigenetic regulator expressed in develo** and mature nociceptive neurons, playing a key role in their specification during...
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Multiple system atrophy: α-Synuclein strains at the neuron-oligodendrocyte crossroad
The aberrant accumulation of α-Synuclein within oligodendrocytes is an enigmatic, pathological feature specific to Multiple system atrophy (MSA)....
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Neuron matters: neuromodulation with electromagnetic stimulation must consider neurons as dynamic identities
Neuromodulation with electromagnetic stimulation is widely used for the control of abnormal neural activity, and has been proven to be a valuable...
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U73122 and m-3M3FBS Regulate the GABAergic Neuron Regeneration via PLCβ in Planarian Dugesia japonica
AbstractThe planarian Dugesia japonica has a powerful regenerative capacity and can regenerate its whole body, including complete and functional...