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Association of oestrogen receptor beta 2 (ERβ2/ERβcx) with outcome of adjuvant endocrine treatment for primary breast cancer – a retrospective study
BackgroundOestrogen receptor beta (ERβ) modulates ERα activity; wild type ERβ (ERβ1) and its splice variants may therefore impact on hormone...
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Cyclooxygenase-2 inhibition: effects on tumour growth, cell cycling and lymphangiogenesis in a xenograft model of breast cancer
Cyclooxygenase-2 (COX-2) is associated with poor-prognosis breast cancer. We used a nude mouse xenograft model to determine the effects of COX-2...
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Microglia activation in sepsis: a case-control study
Backgroundinfection induces an acute phase response that is accompanied by non-specific symptoms collectively named sickness behavior. Recent...
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Osteopontin Knockdown Suppresses Tumorigenicity of Human Metastatic Breast Carcinoma, MDA-MB-435
Elevated expression of osteopontin (OPN), a secreted phosphoglycoprotein, is frequently associated with many transformed cell lines. Various studies...
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Biology of Breast Cancer
Breast carcinogenesis is a multi-step process that initially is recognized histopathologically as a series of preinvasive stages (intermediate... -
Association of c-Raf expression with survival and its targeting with antisense oligonucleotides in ovarian cancer
c-Raf is an essential component of the extracellular related kinase (ERK) signal transduction pathway. Immunohistochemical staining indicated that...