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Biomedicine

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Showing 261-264 of 264 results

  1. Lactate enhances the acid-sensing Na+ channel on ischemia-sensing neurons

    Lactic acid produced by anaerobic metabolism during cardiac ischemia is among several compounds suggested to trigger anginal chest pain 1 , 2 ; however,...

    D. C. Immke, E. W. McCleskey in Nature Neuroscience
    Article 06 August 2001

  2. Acid-sensing ion channel (ASIC) 4 gene: physical map**, genomic organisation, and evaluation as a candidate for paroxysmal dystonia

    Acid-sensing ion channels (ASICs) are protongated Na + channels. They have been implicated with synaptic transmission, pain perception as well as...

    Stefan Gründer, Hyun-Soon Geisler, ... John K Fink in European Journal of Human Genetics
    Article 14 September 2001

  3. Characterisation of a human acid-sensing ion channel (hASIC1a) endogenously expressed in HEK293 cells

    Acid-sensing ion channels (ASICs) are a new and expanding family of proton-gated cation (Na + /Ca 2+ ) channels that are widely expressed in sensory...

    M. Gunthorpe, G. Smith, ... A. Randall in Pflügers Archiv
    Article 01 August 2001

  4. In Brief

    in Nature Reviews Neuroscience
    Article 01 March 2001
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