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Molecular Methods in Neuroscience and Psychiatry
Clinical practice in all fields is working to provide an approach to patients based on their individual characteristics. A personalized approach in...
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Molecular Dynamics Methods for Antibody Design
Complex and coordinated dynamics are closely connected with protein functions, including the binding of antibodies to antigens. Knowledge of such...
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Methods in molecular biology and genetics: looking to the future
In recent decades, advances in methods in molecular biology and genetics have revolutionized multiple areas of the life and health sciences. However,...
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Low-cost molecular methods to characterise gastrointestinal nematode co-infections of goats in Africa
BackgroundVeterinary diagnostics aid intervention strategies, track zoonoses, and direct selective breeding programs in livestock. In ruminants,...
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Molecular Methods for Detection of Βeta-Lactamases
Gram-negative bacterial infections are a substantial cause of health care associated morbidity and mortality among patients. β-lactam antibiotics are...
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Using molecular methods to delineate norovirus outbreaks: a systematic review
Noroviruses are among the major causative agents of human acute gastroenteritis, and the nature of norovirus outbreaks can differ considerably. The...
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Optimizing identification of consensus molecular subtypes in muscle-invasive bladder cancer: a comparison of two sequencing methods and gene sets using FFPE specimens
BackgroundMolecular subtypes predict prognosis in muscle-invasive bladder cancer (MIBC) and are explored as predictive markers. To provide a common...
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Astaxanthin Binding Affinity to DNA: Studied By Fluorescence, Surface Plasmon Resonance and Molecular Docking Methods
Carotenoid astaxanthin (Ax), a pink-red pigment, with its anti-oxidative feature, is useful as a therapeutic element for numerous diseases. The...
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Molecular Dynamics Simulations: Concept, Methods, and Applications
Molecular dynamics (MD) is a computer simulation that deals with biological molecules, such as proteins and nucleic acid, and visualizes their...
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Identification of osteoporosis ferroptosis-related markers and potential therapeutic compounds based on bioinformatics methods and molecular docking technology
Research background and purposeOsteoporosis (OP) is one of the most common bone diseases worldwide, characterized by low bone mineral density and...
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Investigation of intestinal parasites by conventional and molecular methods in children with gastrointestinal system complaints
Intestinal parasitic infections are a global health problem that causes morbidity and mortality, especially in children living in rural areas. In...
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Molecular subgrou** of medulloblastoma in pediatric population using the NanoString assay and comparison with immunohistochemistry methods
PurposeMolecular subgrou** of medulloblastoma has become important due to its impact on risk group stratification. Immunohistochemistry (IHC) has...
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Bacterial Pathogens in Food: Modern Safety Criteria and Methods of Molecular Genetic Analysis
The review is devoted to the issues of improving the food biosafety system by develo** and implementing modern methods of microbiological and...
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Diagnosis of Echinococciasis: Parasitological, Immunological, and Molecular Tools
Echinococcosis is a serious zoonotic disease caused by the larvae of several Echinococcus species forming a hydatid cyst, which can parasitize humans...
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Comparison of gradient diffusion and molecular methods using Allplex™ NG&DR assay (Seegene®) for macrolide and fluoroquinolone screening resistance in Neisseria gonorrhoeae
Antimicrobial resistance in Neisseria gonorrhoeae (NG) is increasing worldwide. Second-line treatments with macrolides or fluoroquinolones are an...
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Technologies to Study Genetics and Molecular Pathways
Over the last few decades, the study of congenital heart disease (CHD) has benefited from various model systems and the development of molecular...
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Molecular Biology of Arboviruses
This memoir traces the evolving studies on the molecular biology of arboviruses in the Strauss lab from 1969 to 2007. Jim began working with Sindbis...
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Principles Governing Molecular Recognition
No interaction—no information. This principle governs the science of molecular sensing, with the limitation that the interaction should be highly...
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Analysis of Spatial Molecular Data
Digital analysis of pathology whole-slide images has been recently gaining interest in the context of cancer diagnosis and treatment. In particular,...
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Combined in Silico Prediction Methods, Molecular Dynamic Simulation, and Molecular Docking of FOXG1 Missense Mutations: Effect on FoxG1 Structure and Its Interactions with DNA and Bmi-1 Protein
FoxG1 encoded by FOXG1 gene is a transcriptional factor interacting with the DNA of targeted genes as well as with several proteins to regulate the...
