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Evaluation of the in vitro activity of ampicillin-sulbactam and cefoperazone-sulbactam against A. Baumannii by the broth disk elution test
To evaluate the in vitro activity of ampicillin-sulbactam and cefoperazone-sulbactam against A. baumannii using the broth disk elution testing, a...
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Association of HLA-G 3′UTR polymorphisms with hepatitis B virus infection in Tunisian population
Hepatitis B virus (HBV) infection is a major public health burden. The mechanisms of immune evasion during chronic HBV (CHB) infection are poorly...
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Elastin-derived peptides (EDPs) as a potential pro-malignancy factor in human leukemia cell lines
AbstractThe extracellular matrix (ECM) is currently considered to be an important factor influencing the migration and progression of cancer cells....
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Equity in action: The Diagnostic Working Group of The Undiagnosed Diseases Network International
Rare diseases are recognized as a global public health priority. A timely and accurate diagnosis is a critical enabler for precise and personalized...
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Comprehensive multiomics analysis of the signatures of gastric mucosal bacteria and plasma metabolites across different stomach microhabitats in the development of gastric cancer
PurposeAs an important component of the microenvironment, the gastric microbiota and its metabolites are associated with tumour occurrence,...
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Sodium Houttuyfonate Ameliorates DSS-induced Colitis Aggravated by Candida albicans through Dectin-1/NF-κB/miR-32-5p/NFKBIZ Axis Based on Intestinal microRNA Profiling
Our previous research indicated that Sodium houttuyfonate (SH) can effectively ameliorate dextran sulfate sodium (DSS)-induced colitis exacerbated by C...
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Platr3/NUDT21/NF-κB Axis Mediates P. gingivalis-Suppressed Cementoblast Mineralization
Porphyromonas gingivalis ( P. gingivalis ) is one of the major pathogens causing periodontitis and apical periodontitis (AP). Long noncoding RNA...
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HLA-E-expressing macrophage polarization and increased NKG2A/CD94 expression in adult-onset Still’s disease
We investigated the phenotypic characteristics of human leukocyte antigen (HLA)-E-expressing macrophages, NKG2A/CD94 expression in T and natural...
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Monensin Suppresses Multiple Features of House Dust Mite-Induced Experimental Asthma in Mice
Despite intense efforts to develop efficient therapeutic regimes for asthma, there is a large demand for novel treatment strategies in this disease....
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Abbott realtime MTB assay for detecting Mycobacterium tuberculosis complex in respiratory specimens: a cost-benefit analysis
PurposeMolecular screening for Mycobacterium tuberculosis (MTB) can lead to rapid empirical treatment inception and reduce hospitalization time and...
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The prognostic value of IgA anti-citrullinated protein antibodies and rheumatoid factor in an early arthritis population with a treat-to-target approach
The mucosal origin hypothesis of rheumatoid arthritis has renewed the interest in IgA autoantibodies, but their added value over IgG...
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Genomic insights into Leminorella grimontii and its chromosomal class A GRI β-lactamase
Leminorella grimontii strain LG-KP-E1-2-T0 was isolated from Zophobas morio larvae. It showed a susceptibility phenotype compatible with the...
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Seven-day antibiotic therapy for Enterobacterales bacteremia in high-risk neutropenic patients: toward a new paradigm
PurposeData on short courses of antibiotic therapy for Enterobacterales bacteremia in high-risk neutropenic patients are limited. The aim of the...
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Suppressing SENP1 inhibits esophageal squamous carcinoma cell growth via SIRT6 SUMOylation
PurposeEsophageal squamous cell carcinoma (ESCC) is a prevalent tumor in the gastrointestinal tract, but our understanding of the molecular...
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Static and temporal dynamic alterations of regional homogeneity in chronic insomnia: a resting-state fMRI study
To explore brain function alterations in chronic insomnia (CI). 65 CI patients and 48 healthy controls were included to analyze abnormal alterations...
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A Comprehensive Overview of NF1 Mutations in Iranian Patients
Neurofibromatosis type 1 (NF1) is a genetic disorder caused by mutations in the NF1 gene. This disorder shows nearly complete penetrance and high...
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Peroxiredoxin 6 Protects Pulmonary Epithelial Cells From Cigarette-related Ferroptosis in Chronic Obstructive Pulmonary Disease
Peroxiredoxin 6 (PRDX6) has a protective effect on pulmonary epithelial cells against cigarette smoke (CS)-induced ferroptosis. This study...
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Oral HPV infection clearance and acquisition after nonavalent vaccination in men who have sex with men and transgender women: a prospective analysis
Oral HPV infection is the main risk factor for the development of oropharyngeal carcinoma. Men who have sex with men (MSM), especially if living with...
