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  1. A comprehensive cancer center in the cloud powered by AI can reduce health disparities

    Wilfred Ngwa, Arthur Pressley, ... Kenneth Ngwa in Nature Medicine
    Article 15 July 2024

  2. Outpatient reception via collaboration between nurses and a large language model: a randomized controlled trial

    Reception is an essential process for patients seeking medical care and a critical component influencing the healthcare experience. However, current...

    Peixing Wan, Zigeng Huang, ... Er** Long in Nature Medicine
    Article 15 July 2024

  3. The dual role of FSP1 in programmed cell death: resisting ferroptosis in the cell membrane and promoting necroptosis in the nucleus of THP-1 cells

    Background

    Acute monocytic leukemia-M5 (AML-M5) remains a challenging disease due to its high morbidity and poor prognosis. In addition to the...

    **aoqian Tan, Yinling He, ... Wei **e in Molecular Medicine
    Article Open access 15 July 2024

  4. Understanding lactate in the development of Hepatitis B virus-related hepatocellular carcinoma

    Hepatitis B Virus (HBV) is a hepatotropic virus that can establish a persistent and chronic infection in humans. Chronic hepatitis B (CHB) infection...

    Sheida Behzadi Sheikhrobat, Shahab Mahmoudvand, ... Somayeh Shokri in Infectious Agents and Cancer
    Article Open access 15 July 2024

  5. Autoantibodies Neutralizing GM-CSF in HIV-Negative Colombian Patients Infected with Cryptococcus gattii and C. neoformans

    Background

    Cryptococcosis is a life-threatening disease caused by Cryptococcus neoformans or C. gattii . Neutralizing autoantibodies (auto-Abs)...

    Carlos A. Arango-Franco, Julian Rojas, ... Andrés A. Arias in Journal of Clinical Immunology
    Article Open access 15 July 2024

  7. Stability of N-type inactivation and the coupling between N-type and C-type inactivation in the Aplysia Kv1 channel

    The voltage-dependent potassium channels (Kv channels) show several different types of inactivation. N-type inactivation is a fast inactivating...

    Tokunari Iwamuro, Kazuki Itohara, Yasuo Furukawa in Pflügers Archiv - European Journal of Physiology
    Article Open access 15 July 2024

  8. BACH2 regulates diversification of regulatory and proinflammatory chromatin states in TH17 cells

    Interleukin-17 (IL-17)-producing helper T (T H 17) cells are heterogenous and consist of nonpathogenic T H 17 (npT H 17) cells that contribute to tissue...

    Pratiksha I. Thakore, Alexandra Schnell, ... Aviv Regev in Nature Immunology
    Article 15 July 2024

  9. Advancements in pathogen immunity and signaling

    Mads Gyrd-Hansen, Anna Kajaste-Rudnitski, ... Matteo Iannacone in Nature Immunology
    Article 15 July 2024

  10. A life-course multisectoral approach to precision health in LMICs

    Stefan Swartling Peterson, Olive Kobusingye, ... Peter Waiswa in Nature Medicine
    Article 15 July 2024

  11. Evaluation of chimeric recombinant antigens for the serodiagnosis of Trypanosoma cruzi in dogs: a promising tool for Chagas disease surveillance

    Background

    Chagas disease (CD), a neglected parasitic disease caused by Trypanosoma cruzi , poses a significant health threat in Latin America and has...

    Natália Dantas Fontes, Fernanda Lopes Habib, ... Fred Luciano Neves Santos in Parasites & Vectors
    Article Open access 15 July 2024

  12. Asymptomatic malaria in pregnancy and associated risk factors in Majang Zone, Gambella Region, Southwest Ethiopia: a hard-to-reach malaria hotspot

    Background

    Asymptomatic malaria in pregnancy (AMiP) is a daunting public health problem with multifaceted adverse outcomes for mothers, fetuses,...

    Aklilu Alemayehu, Ashenafi Abossie, ... Delenasaw Yewhalaw in Malaria Journal
    Article Open access 15 July 2024

  13. Cytogenomic description of a Mexican cohort with differences in sex development

    Background

    Differences in Sex Development (DSD) is a heterogeneous group of congenital alterations that affect inner and/or outer primary sex...

    Grecia C. Olivera-Bernal, Marlon De Ita-Ley, ... Haydeé Rosas-Vargas in Molecular Cytogenetics
    Article Open access 15 July 2024

  14. Consumer wearable devices for evaluation of heart rate control using digoxin versus beta-blockers: the RATE-AF randomized trial

    Consumer-grade wearable technology has the potential to support clinical research and patient management. Here, we report results from the RATE-AF...

    Simrat K. Gill, Andrey Barsky, ... Dipak Kotecha in Nature Medicine
    Article Open access 15 July 2024

  15. The immunology of systemic lupus erythematosus

    Understanding the pathogenesis and clinical manifestations of systemic lupus erythematosus (SLE) has been a great challenge. Reductionist approaches...

    George C. Tsokos in Nature Immunology
    Article 15 July 2024

  18. Unravelling heterogeneous malaria transmission dynamics in the Peruvian Amazon: insights from a cross-sectional survey

    Background

    Malaria remains a global health challenge, particularly in Peru's Loreto region. Despite ongoing efforts, high infection rates and...

    Viviana Pinedo-Cancino, Katty M. Arista, ... Lastenia Ruíz-Mesia in Malaria Journal
    Article Open access 15 July 2024

  20. Characterization of 13 Novel Genetic Variants in Genes Associated with Epilepsy: Implications for Targeted Therapeutic Strategies

    Background

    Childhood epilepsies are caused by heterogeneous underlying disorders where approximately 40% of the origins of epilepsy can be attributed...

    Marina Andjelkovic, Kristel Klaassen, ... Maja Stojiljkovic in Molecular Diagnosis & Therapy
    Article Open access 14 July 2024
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