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Exploratory Mass Spectrometry of Cerebrospinal Fluid from Persons with Autopsy-Confirmed LATE-NC
Common neuropathologies associated with dementia include Alzheimer’s disease neuropathologic change (ADNC) and limbic-predominant age-related TDP-43...
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MicroRNA-21 modulates brown adipose tissue adipogenesis and thermogenesis in a mouse model of polycystic ovary syndrome
BackgroundPolycystic ovary syndrome (PCOS), the most common endocrine disorder in premenopausal women, is associated with increased obesity,...
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The quassinoids bruceines A–M: pharmacology, mechanism of action, synthetic advance, and pharmacokinetics—a review
Bruceines A–L are among the quassinoid representatives found in the medicinal plant Brucea javanica (L.). An overview of their pharmacological...
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Clarifying middle authorship contributions to reduce abuses in science publishing and assessment of top-ranked SJR biochemistry and pharmacology journals’ authorship criteria
So-called “middle authors,” being neither the first, last, nor corresponding author of an academic paper, have made increasing relative contributions...
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Strategies for modeling aging and age-related diseases
The ability to reprogram patient-derived-somatic cells to IPSCs (Induced Pluripotent Stem Cells) has led to a better understanding of aging and...
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Glycogenolysis-Induced Astrocytic Ser**1 Expression Regulates Neuroinflammatory Effects on Hippocampal neuron
The bacterial pathogen, lipopolysaccharide (LPS), elicits microglial response and induces cytokine secretion that subsequently activates astrocytes....
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CSF formation rate—a potential glymphatic flow parameter in hydrocephalus?
BackgroundStudies indicate that brain clearance via the glymphatic system is impaired in idiopathic normal pressure hydrocephalus (INPH). This has...
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Modulation of miR-155-5p signalling via 5-ASA for the prevention of high microsatellite instability: an in vitro study using human epithelial cell lines
5-aminosalicylic acid (5-ASA) is a first-line treatment for maintaining colitis remission. It is a highly effective, safe, and well-tolerated drug...
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Use of cortical hemodynamic responses in digital therapeutics for upper limb rehabilitation in patients with stroke
BackgroundStroke causes long-term disabilities, highlighting the need for innovative rehabilitation strategies for reducing residual impairments....
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The cerebellum modulates thirst
The cerebellum, a phylogenetically ancient brain region, has long been considered strictly a motor control structure. Recent studies have implicated...
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Epicatechin as a promising agent against arsenic-induced neurobehavioral toxicity in NMRI mice: behavioral and biochemical alterations
Epicatechin (Epi) is one of the most abundant flavonoids present in different fruits and tea leaves. Emerging research illuminates the promising...
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Influence of sustained mild dehydration on thermoregulatory and cognitive functions during prolonged moderate exercise
PurposeThe current study investigated whether sustained mild dehydration affects thermoregulatory function and cognitive performance during prolonged...
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Investigating the Impact of Intracerebroventricular Streptozotocin on Female Rats with and without Ovaries: Implications for Alzheimer’s Disease
To contribute to research on female models of Alzheimer’s disease (AD), our aim was to study the effect of intracerebroventricular (ICV) injection of...
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COVID-19-Associated Cerebellar Ataxia: A Case Series
COVID-19-associated cerebellar ataxia has rarely been reported and its clinical characteristics remain understudied. This study aims to report...
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Antiferromagnetic artificial neuron modeling of the withdrawal reflex
Replicating neural responses observed in biological systems using artificial neural networks holds significant promise in the fields of medicine and...
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The Role of the Intestinal Flora and Its Derivatives in Neurocognitive Disorders: A Narrative Review from Surgical Perspective
Perioperative neurocognitive dysfunction is a significant concern for population health, impacting postoperative recovery and increasing the...
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A critical appraisal on the involvement of plant-based extracts as neuroprotective agents (2012–2022): an effort to ease out decision-making process for researchers
The purpose of this review study is to provide a condensed compilation of 164 medicinal plants that have been investigated for their neuroprotective...
