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Will a lack of fabric durability be their downfall? Impact of textile durability on the efficacy of three types of dual-active-ingredient long-lasting insecticidal nets: a secondary analysis on malaria prevalence and incidence from a cluster-randomized trial in north-west Tanzania
BackgroundThe Dual-Active Ingredient long-lasting insecticidal nets (Dual-AI LLIN) have been developed to counteract the reduced efficacy of...
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Myocarditis associated with COVID-19 vaccination
Following the start of the COVID-19 vaccination campaign, the adverse events of myocarditis and pericarditis were linked mainly to mRNA COVID-19...
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Worse pulmonary function in association with cumulative exposure to nanomaterials. Hints of a mediation effect via pulmonary inflammation
BackgroundToday, nanomaterials are broadly used in a wide range of industrial applications. Such large utilization and the limited knowledge on to...
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Diagnostic accuracy of an automated microscope solution (miLab™) in detecting malaria parasites in symptomatic patients at point-of-care in Sudan: a case–control study
BackgroundMicroscopic detection of malaria parasites is labour-intensive, time-consuming, and expertise-demanding. Moreover, the slide interpretation...
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Personalized therapy in oncology: melanoma as a paradigm for molecular-targeted treatment approaches
In recent decades, the field of systemic cancer treatment has seen remarkable changes due to advancements in the understanding of cancer’s biology,...
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UBTF mediates activation of L3MBTL2 to suppress NISCH expression through histone H2AK119 monoubiquitination modification in breast cancer
Lethal(3)malignant brain tumor-like protein 2 (L3MBTL2) has been related to transcriptional inhibition and chromatin compaction. Nevertheless, the...
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Centenarians, semi and supercentenarians, COVID-19 and Spanish flu: a serological assessment to gain insight into the resilience of older centenarians to COVID-19
BackgroundAlthough it is well known that the older people have been the most susceptible to COVID-19, there are conflicting data on the...
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Systemic prime mucosal boost significantly increases protective efficacy of bivalent RSV influenza viral vectored vaccine
Although licensed vaccines against influenza virus have been successful in reducing pathogen-mediated disease, they have been less effective at...
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Total antioxidant status levels in malaria: a systematic review and meta-analysis
BackgroundMalaria, a severe health threat, significantly affects total antioxidant status (TAS) levels, leading to considerable oxidative stress....
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High prevalence and risk of malaria among asymptomatic individuals from villages with high prevalence of artemisinin partial resistance in Kyerwa district of Kagera region, north-western Tanzania
BackgroundAlthough Tanzania adopted and has been implementing effective interventions to control and eventually eliminate malaria, the disease is...
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A safe and potentiated multi-type HPV L2-E7 nanoparticle vaccine with combined prophylactic and therapeutic activity
Persistent infection with high-risk human papillomavirus (HPV) is widely recognized as the primary cause of cervical and other malignant cancers....
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A gH/gL-encoding replicon vaccine elicits neutralizing antibodies that protect humanized mice against EBV challenge
Epstein-Barr virus (EBV) is associated with several malignancies, neurodegenerative disorders and is the causative agent of infectious mononucleosis....
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Adoptive NK cell therapy: a potential revolutionary approach in longevity therapeutics
The aging process intricately involves immune system dynamics, with a crucial role in managing senescent cells (SNCs) and their senescence-associated...
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The direct effect of SARS-CoV-2 virus vaccination on human ovarian granulosa cells explains menstrual irregularities
Following administration of the SARS-CoV-2 vaccine, many women worldwide reported short-term menstrual irregularities. Although menstrual bleeding,...
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Heavy-metal associated breast cancer and colorectal cancer hot spots and their demographic and socioeconomic characteristics
PurposeCancer registries offer an avenue to identify cancer clusters across large populations and efficiently examine potential environmental harms...
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Fine-scale maps of malaria incidence to inform risk stratification in Laos
BackgroundMalaria risk maps are crucial for controlling and eliminating malaria by identifying areas of varying transmission risk. In the Greater...
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Single cell transcriptome analysis identified a unique neutrophil type associated with Alzheimer’s disease
BackgroundNeutrophils play an essential role in Alzheimer’s disease (AD) pathology. However, the extent of their heterogeneity remains poorly...
