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Recursive partitioning analysis for survival stratification and early imaging prediction of molecular biomarker in glioma patients
BackgroundGlioma is the most common primary brain tumor with high mortality and disability rates. Recent studies have highlighted the significant...
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Analysis of the immune-inflammatory indices for patients with metastatic hormone-sensitive and castration-resistant prostate cancer
BackgroundInflammation plays a pivotal role in the progression of prostate cancer (PCa). Several immune-inflammatory indices, including neutrophil to...
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A randomised controlled trial of Standard Of Care versus RadioAblaTion in Early Stage HepatoCellular Carcinoma (SOCRATES HCC)
BackgroundTherapeutic options for early-stage hepatocellular carcinoma (HCC) in individual patients can be limited by tumor and location, liver...
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Prognostic and clinicopathological significance of tertiary lymphoid structure in non-small cell lung cancer: a systematic review and meta-analysis
BackgroundNon-small cell lung cancer (NSCLC) is the primary reason for cancer-related deaths globally. Tertiary lymphoid structure (TLS) is an...
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Selective anti-tumor activity of glutathione-responsive abasic site trap** agent in anaplastic thyroid carcinoma
Anaplastic thyroid carcinoma (ATC) is a rare but highly aggressive thyroid cancer with poor prognosis. Killing cancer cells by inducing DNA damage or...
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Antitumour effects of SFX-01 molecule in combination with ionizing radiation in preclinical and in vivo models of rhabdomyosarcoma
BackgroundDespite a multimodal approach including surgery, chemo- and radiotherapy, the 5-year event-free survival rate for rhabdomyosarcoma (RMS),...
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Comparative immune profiling of pancreatic ductal adenocarcinoma progression among South African patients
BackgroundPancreatic Ductal Adenocarcinoma (PDAC) is an aggressive cancer characterized by an immunosuppressive microenvironment. Patients from...
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Ultrasound-based nomogram to predict the recurrence in papillary thyroid carcinoma using machine learning
Background and aimsThe recurrence of papillary thyroid carcinoma (PTC) is not unusual and associated with risk of death. This study is aimed to...
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Melanoma risk, tumour stage, and melanoma-specific mortality in individuals with diabetes: a systematic review and meta-analysis
BackgroundCancer has become the leading diabetes-related cause of death in high-income countries, and more knowledge is needed to clarify the impact...
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KK-LC-1, a biomarker for prognosis of immunotherapy for primary liver cancer
PurposeThere is mounting evidence that patients with liver cancer can benefit from Immune checkpoint inhibitors. However, due to the high cost and...
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Clinical applications of telemedicine services using a regional telemedicine platform for cancer treatment: a cross-sectional study
BackgroundTelemedicine is beneficial for improving treatment efficiency and reducing medical expenses of cancer patients. This study focuses on...
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A transversal cross-sectional study of factors related to HPV vaccination status and cancer screening participation among French women aged 25–40
BackgroundIn 2020, uterine cervical cancer (UCC) was the 12th most common cancer among women in France and the 4th worldwide. French health...
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Participants’ perspectives of being recruited into a randomised trial of a weight loss intervention before colorectal cancer surgery: a qualitative interview study
BackgroundThe period between cancer diagnosis and surgery presents an opportunity for trials to assess the feasibility of behaviour change...
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Clinical outcome predictors for metastatic renal cell carcinoma: a retrospective multicenter real-life case series
Over the last decades, the therapeutic armamentarium of metastatic renal cell carcinoma (mRCC) has been revolutionized by the advent of...
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Exploring the causal association between uric acid and lung cancer in east Asian and European populations: a mendelian randomization study
BackgroundLung cancer still ranks first in the mortality rate of cancer. Uric acid is a product of purine metabolism in humans. Its presence in the...
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Retrospective multicenter study of elderly patients with platinum-sensitive relapsed ovarian cancer treated with trabectedin and pegylated liposomal doxorubicin (pld) in a real-world setting: a geico study
BackgroundTrabectedin in combination with pegylated liposomal doxorubicin (PLD) is approved for the treatment of patients with platinum-sensitive...
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Differentiation of glioma and solitary brain metastasis: a multi-parameter magnetic resonance imaging study using histogram analysis
BackgroundDifferentiation of glioma and solitary brain metastasis (SBM), which requires biopsy or multi-disciplinary diagnosis, remains sophisticated...
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It’s about time: mitigating cancer-related cognitive impairments through findings from computational models of the Wisconsin Card Sorting Task
BackgroundMany cancer survivors experience cancer-related cognitive impairment (CRCI), often with significant negative consequences across various...
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The clinical significance of inflammatory mediators in predicting obesity and progression-free survival in patients with adult-onset Craniopharyngioma
BackgroundCraniopharyngioma (CP) is a rare malformational tumor characterized by high rates of recurrence and morbid obesity. However, the role of...
