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Understand the Stabilization Engineering of Ascorbic Acid, Map** the Scheme for Stabilization, and Advancement.
AbstractVitamin C is extensively used in cosmetic formulation, howbeit stability is the supreme demerit that limits its use in beautifying products....
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A Coaching-Based Leadership Program for Women Postdoctoral Fellows at the National Cancer Institute that Cultivates Self-confidence and Persistence in STEMM
Despite making strides in gender equality, women in Science, Technology, Engineering, Mathematics, and Medicine (STEMM) continue to face a persistent...
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Comparative analysis of two novel complete genomes of myxoma virus vaccine strains
Myxoma virus (MYXV) is a double-stranded DNA-containing virus of the family Poxviridae , genus Leporipoxvirus . MYXV is an important model virus for...
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Paclitaxel in colon cancer management: from conventional chemotherapy to advanced nanocarrier delivery systems
Paclitaxel, a potent chemotherapeutic agent derived from the bark of the Pacific yew tree, has demonstrated significant efficacy in the treatment of...
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Transplant of fecal microbiota from healthy young mice relieves cognitive defects in late-stage diabetic mice by reducing metabolic disorders and neuroinflammation
Fecal microbiota transplant (FMT) is becoming as a promising area of interest for treating refractory diseases. In this study, we investigated the...
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Heterogeneity in choice models of addiction: the role of context
RationaleTheories of addiction guide scientific progress, funding priorities, and policy development and ultimately shape how people experiencing or...
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FXR activation remodels hepatic and intestinal transcriptional landscapes in metabolic dysfunction-associated steatohepatitis
The escalating obesity epidemic and aging population have propelled metabolic dysfunction-associated steatohepatitis (MASH) to the forefront of...
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Evaluation of the Protective Effects of Lugol’s Solution in Rats Poisoned with Aluminum Phosphide (Rice Tablets)
Aluminum phosphide (AlP) is the main component of rice tablets (a pesticide), which produces phosphine gas (PH3) when exposed to stomach acid. The...
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Carotid artery transplantation of brain endothelial cells enhances neuroprotection and neurorepair in ischaemic stroke rats
Brain microvascular endothelial cells (BMECs), an important component of the neurovascular unit, can promote angiogenesis and synaptic formation in...
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Molecular functions of HAX1 during disease progress
HCLS1-associated protein X-1 (HAX1) is a newly discovered multifunctional cell regulatory protein that is widely expressed in cells and has a close...
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Investigating a Novel Two-Bag N-Acetylcysteine Regimen for Acetaminophen Toxicity
BackgroundAcetaminophen toxicity remains one of the most common causes of liver failure and is treated with a course of n-acetylcysteine (NAC). This...
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Rab11b promotes M1-like macrophage polarization by restraining autophagic degradation of NLRP3 in alcohol-associated liver disease
Macrophage polarization is vital to mounting a host defense or repairing tissue in various liver diseases. Excessive activation of the NLR family...
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In Vitro Ciclopirox Glucuronidation in Liver Microsomes from Humans and Various Experimental Animals
Background and ObjectiveCiclopirox is a widely used antifungal drug, redisposition of which has drawn increasing attentions due to multiple promising...
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Celecoxib inhibits NLRP1 inflammasome pathway in MDA-MB-231 Cells
NLRP1 is predominantly overexpressed in breast cancer tissue, and the evaluated activation of NLRP1 inflammasome is associated with tumor growth,...
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The undeclared use of third-party service providers in academic publishing is unethical: an epistemic reflection and sco** review
There is a substantial body of scientific literature on the use of third-party services (TPS) by academics to assist as “publication consultants” in...
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Crosstalk between gut–brain axis: unveiling the mysteries of gut ROS in progression of Parkinson’s disease
“Path to a good mood lies through the gut.” This statement seems to imply that it has long been believed that the gut is connected with the brain....
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Bexagliflozin: a comprehensive review of a recently approved SGLT2 inhibitor for the treatment of type 2 diabetes mellitus
Type 2 diabetes mellitus (T2DM) remains a major global health threat, claiming millions of lives annually. Despite recent advancements in managing...
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Knockout Transporter Cell Lines to Assess Substrate Potential Towards Efflux Transporters
P-glycoprotein (P-gp), breast cancer resistance protein (BCRP) and multidrug resistance transporter 2 (MRP2) are efflux transporters involved in the...
