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METTL3-mediated NDUFB5 m6A modification promotes cell migration and mitochondrial respiration to promote the wound healing of diabetic foot ulcer
BackgroundDiabetic foot ulcer (DFU) is the most devastating complication of diabetes mellitus (DM) and plays a major role in disability and death in...
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Quinoa and its Co-Products as Ingredients for the Development of Dairy Analogs and Hybrid Dairy Products
Purpose of ReviewThis review intends to explore the potential of quinoa and its co-products as ingredients to alternative dairy foods (plant-based...
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Recursive partitioning analysis for survival stratification and early imaging prediction of molecular biomarker in glioma patients
BackgroundGlioma is the most common primary brain tumor with high mortality and disability rates. Recent studies have highlighted the significant...
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IκBα kinase inhibitor BAY 11-7082 promotes anti-tumor effect in RAS-driven cancers
BackgroundOncogenic mutations in the RAS gene are associated with uncontrolled cell growth, a hallmark feature contributing to tumorigenesis. While...
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Unbiasedly decoding the tumor microenvironment with single-cell multiomics analysis in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy with a poor prognosis and limited therapeutic options. Research on the...
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Flexible multitask computation in recurrent networks utilizes shared dynamical motifs
Flexible computation is a hallmark of intelligent behavior. However, little is known about how neural networks contextually reconfigure for different...
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Decoding protein–RNA interactions using CLIP-based methodologies
Protein–RNA interactions are central to all RNA processing events, with pivotal roles in the regulation of gene expression and cellular functions....
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The common bisulfite-conversion-based techniques to analyze DNA methylation in human cancers
DNA methylation is an important molecular modification that plays a key role in the expression of cancer genes. Evaluation of epigenetic changes,...
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Invasive recurrence after breast conserving treatment of ductal carcinoma in situ of the breast in the Netherlands: time trends and the association with tumour grade
BackgroundThe first aim of this study was to examine trends in the risk of ipsilateral invasive breast cancer (iIBC) after breast-conserving surgery...
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EMBER creates a unified space for independent breast cancer transcriptomic datasets enabling precision oncology
Transcriptomics has revolutionized biomedical research and refined breast cancer subty** and diagnostics. However, wider use in clinical practice...
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Dielectric spectroscopy of blood cells for express monitoring of the Ehrich ascites carcinoma stages in the mice
This study addresses the possibility of using rank distributions of leukocyte formula and dielectric indicators of blood cell suspensions as...
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Stromal lymphocytes are associated with upgrade of B3 breast lesions
Various histopathological, clinical and imaging parameters have been evaluated to identify a subset of women diagnosed with lesions with uncertain...