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The antiarrhythmic drugs amiodarone and dronedarone inhibit intoxication of cells with pertussis toxin
Pertussis toxin (PT) is a virulent factor produced by Bordetella pertussis , the causative agent of whoo** cough. PT exerts its pathogenic effects...
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Evaluation of the effect of empagliflozin on prevention of atrial fibrillation after coronary artery bypass grafting: a double-blind, randomized, placebo-controlled trial
This study is aimed at evaluating the effect of empagliflozin in preventing atrial fibrillation after coronary artery bypass grafting (CABG)....
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Assessing focal spot alignment in clinical linear accelerators: a comprehensive evaluation with triplet phantoms
A fundamental parameter to evaluate the beam delivery precision and stability on a clinical linear accelerator (linac) is the focal spot position...
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The verification of the utility of a commercially available phantom combination for quality control in contrast-enhanced mammography
Contrast-enhanced mammography is being increasingly implemented clinically, providing much improved contrast between tumour and background...
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Multifaceted role of phytoconstituents based nano drug delivery systems in combating TNBC: A paradigm shift from chemical to natural
Triple negative breast cancer is considered to be a malignancy of grave concern with limited routes of treatment due to the absence of specific...
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Instrumented Mouthguard Decoupling Affects Measured Head Kinematic Accuracy
Many recent studies have used boil-and-bite style instrumented mouthguards to measure head kinematics during impact in sports. Instrumented...
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Evaluating the effect of sodium alginate and sodium carboxymethylcellulose on pulmonary delivery of levofloxacin spray-dried microparticles
BackgroundPatients with cystic fibrosis commonly suffer from lung infections caused by Pseudomonas aeruginosa . Recently, the Levofloxacin (LVF)...
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Potential Role of Dipeptidyl Peptidase−4 in Regulating Mitochondria and Oxidative Stress in Cardiomyocytes
Oxidative stress causes mitochondrial damage and bioenergetic dysfunction and inhibits adenosine triphosphate production, contributing to the...
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High-Throughput Fluorometric Assay For Quantifying Polysorbate In Biopharmaceutical Products Using Micelle Activated Fluorescence Probe N-Phenyl-1-Naphthylamine
PurposePolysorbates are among the most used surfactants in biopharmaceutical products containing proteins. Our work aims to develop a high-throughput...
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Probabilistic Finite Element Analysis of Human Rib Biomechanics: A Framework for Improved Generalizability
In dynamic impact events, thoracic injuries often involve rib fractures, which are closely related to injury severity. Previous studies have...
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Insight into the Manipulation Mechanism of Polymorphic Transformation by Polymers: A Case of Cimetidine
PurposeEmploying polymer additives is an effective strategy to realize the manipulation of polymorphic transformation. However, the manipulation...
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Map** the landscape: a bibliometric study of global chimeric antigen receptor T cell immunotherapy research
The rise of immunotherapy provided new approaches to cancer treatment. We aimed to describe the contribution of chimeric antigen receptor T cell...
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Review of Machine Learning Techniques in Soft Tissue Biomechanics and Biomaterials
Background and ObjectiveAdvanced material models and material characterization of soft biological tissues play an essential role in pre-surgical...
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Exploring the link between metformin use and adhesive capsulitis of the shoulder: a retrospective cohort study in Taiwan
The risk of adhesive capsulitis of shoulder in diabetic patients taking metformin has not been evaluated. We aimed for evaluating the relative risk...
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Sex differences in behavior, cognitive, and physiological recovery following methamphetamine administration
Intact executive functions are required for proper performance of cognitive tasks and relies on balance of excitatory and inhibitory (E/I)...
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Peroxiredoxin 6 Protects Pulmonary Epithelial Cells From Cigarette-related Ferroptosis in Chronic Obstructive Pulmonary Disease
Peroxiredoxin 6 (PRDX6) has a protective effect on pulmonary epithelial cells against cigarette smoke (CS)-induced ferroptosis. This study...
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Does a postmortem redistribution affect the concentrations of the 7 azaindole-derived synthetic cannabinoid 5F-MDMB-P7AICA in tissues and body fluids following pulmonary administration to pigs?
Many fatal intoxications have been reported in connection with the consumption of newer, highly potent synthetic cannabinoids. Yet, a possible...
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Impact of Chemotherapy Educational Videos for Patients with Acute Myeloid Leukemia
Patient education in acute myeloid leukemia (AML) has become increasingly complex with the introduction of new treatments and chemotherapy regimens....
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Airbag Vests in Equestrian Sports: Is Use Associated with Harm?
Airbag vests (AV) are increasingly popular in equestrian sports. The efficacy of AV in protecting against serious injury has not been adequately...
