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Cardiovascular history and risk of idiopathic Parkinson’s disease: a cross-sectional observational study
BackgroundParkinson's disease (PD), while often associated with its distinctive motor symptoms, can also exert a notable impact on the cardiovascular...
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Simulated complexes formed from a set of postsynaptic proteins suggest a localised effect of a hypomorphic Shank mutation
BackgroundThe postsynaptic density is an elaborate protein network beneath the postsynaptic membrane involved in the molecular processes underlying...
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Changes of brain functional network in Alzheimer’s disease and frontotemporal dementia: a graph-theoretic analysis
BackgroundAlzheimer’s disease (AD) and frontotemporal dementia (FTD) are the two most common neurodegenerative dementias, presenting with similar...
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Persistent vocal learning in an aging open-ended learner reflected in neural FoxP2 expression
BackgroundMost vocal learning species exhibit an early critical period during which their vocal control neural circuitry facilitates the acquisition...
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The angiotensin II receptors type 1 and 2 modulate astrocytes and their crosstalk with microglia and neurons in an in vitro model of ischemic stroke
BackgroundAstrocytes are the most abundant cell type of the central nervous system and are fundamentally involved in homeostasis, neuroprotection,...
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Diabetes mellitus and risk of incident dementia in APOE ɛ4 carriers: an updated meta-analysis
Background and aimDiabetes raises the risk of dementia, mortality, and cognitive decline in the elderly, potentially because of hereditary variables...
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Autism spectrum disorders detection based on multi-task transformer neural network
Autism Spectrum Disorders (ASD) are neurodevelopmental disorders that cause people difficulties in social interaction and communication. Identifying...
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Automated glioblastoma patient classification using hypoxia levels measured through magnetic resonance images
IntroductionThe challenge of treating Glioblastoma (GBM) tumors is due to various mechanisms that make the tumor resistant to radiation therapy. One...
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Central nervous system anomalies in 41 Chinese children incontinentia pigmenti
IntroductionIncontinentia pigmenti (IP) is a rare neuroectodermal dysplasia caused by a defect in the IKBKG gene. The pathogenesis of central...
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Characterizing dysregulations via cell-cell communications in Alzheimer’s brains using single-cell transcriptomes
BackgroundAlzheimer’s disease (AD) is a devastating neurodegenerative disorder affecting 44 million people worldwide, leading to cognitive decline,...
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A new era in cognitive neuroscience: the tidal wave of artificial intelligence (AI)
Translating artificial intelligence techniques into the realm of cognitive neuroscience holds promise for significant breakthroughs in our ability to...
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Computational modeling of light processing in the habenula and dorsal raphe based on laser ablation of functionally-defined cells
BackgroundThe habenula is a major regulator of serotonergic neurons in the dorsal raphe, and thus of brain state. The functional connectivity between...
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The effects of multi-colour light filtering glasses on human brain wave activity
The prevalence of electronic screens in modern society has significantly increased our exposure to high-energy blue and violet light wavelengths....
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The effect of early mobilisation (< 14 days) on pathophysiological and functional outcomes in animals with induced spinal cord injury: a systematic review with meta-analysis
IntroductionThe optimum time to mobilise (standing, walking) following spinal cord injury (SCI) is unknown but may have implications for patient...
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Neuroscience of taste: unlocking the human taste code
Since antiquity human taste has been divided into 4–5 taste qualities. We realized in the early 1970s that taste qualities vary between species and...
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Auditory brainstem responses are resistant to pharmacological modulation in Sprague Dawley wild-type and Neurexin1α knockout rats
Sensory processing in the auditory brainstem can be studied with auditory brainstem responses (ABRs) across species. There is, however, a limited...
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Serum interleukin-17 A and homocysteine levels in children with autism
BackgroundAutism Spectrum Disorder (ASD) is a neurodevelopmental condition that typically emerges early in childhood. This study aimed to explore the...
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Administration methods and dosage of poly(lactic acid)-glycol intervention to myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalitis mice
BackgroundMyelin oligodendrocyte glycoprotein-associated disorders (MOGAD) is an autoimmune central nervous system disease. Antigen-specific immune...
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Discrimination of the moving direction is improved depending on the pattern of the mechanical tactile stimulation intervention
BackgroundThe mechanical tactile stimulation, such as plastic pins and airflow-driven membrane, induces cortical activity. The cortical activity...
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Resistance training modifies of serum levels of matrix metalloproteinase 2 and tissue inhibitor of matrix metalloproteinases in multiple sclerosis women - a randomized controlled trail
The objectives of the present study was to investigate the effects of resistance training (RT) on serum levels of controlling blood-brain barrier...
