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Effects of Sex Steroids on Innate and Adaptive Immunity
Estrogens and androgens are classically recognized as reproductive sex steroid hormones because of their well-documented effects on reproductive... -
Outpatient reception via collaboration between nurses and a large language model: a randomized controlled trial
Reception is an essential process for patients seeking medical care and a critical component influencing the healthcare experience. However, current...
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Understanding lactate in the development of Hepatitis B virus-related hepatocellular carcinoma
Hepatitis B Virus (HBV) is a hepatotropic virus that can establish a persistent and chronic infection in humans. Chronic hepatitis B (CHB) infection...
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Redundancy in microbiota-mediated suppression of the soybean cyst nematode
BackgroundSoybean cyst nematodes (SCN) as animal parasites of plants are not usually interested in killing the host but are rather focused on...
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Autoantibodies Neutralizing GM-CSF in HIV-Negative Colombian Patients Infected with Cryptococcus gattii and C. neoformans
BackgroundCryptococcosis is a life-threatening disease caused by Cryptococcus neoformans or C. gattii . Neutralizing autoantibodies (auto-Abs)...
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BACH2 regulates diversification of regulatory and proinflammatory chromatin states in TH17 cells
Interleukin-17 (IL-17)-producing helper T (T H 17) cells are heterogenous and consist of nonpathogenic T H 17 (npT H 17) cells that contribute to tissue...
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Genomic representativeness and chimerism in large collections of SAGs and MAGs of marine prokaryoplankton
BackgroundSingle amplified genomes (SAGs) and metagenome-assembled genomes (MAGs) are the predominant sources of information about the coding...
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Evaluation of chimeric recombinant antigens for the serodiagnosis of Trypanosoma cruzi in dogs: a promising tool for Chagas disease surveillance
BackgroundChagas disease (CD), a neglected parasitic disease caused by Trypanosoma cruzi , poses a significant health threat in Latin America and has...
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Asymptomatic malaria in pregnancy and associated risk factors in Majang Zone, Gambella Region, Southwest Ethiopia: a hard-to-reach malaria hotspot
BackgroundAsymptomatic malaria in pregnancy (AMiP) is a daunting public health problem with multifaceted adverse outcomes for mothers, fetuses,...
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Consumer wearable devices for evaluation of heart rate control using digoxin versus beta-blockers: the RATE-AF randomized trial
Consumer-grade wearable technology has the potential to support clinical research and patient management. Here, we report results from the RATE-AF...
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The immunology of systemic lupus erythematosus
Understanding the pathogenesis and clinical manifestations of systemic lupus erythematosus (SLE) has been a great challenge. Reductionist approaches...
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Food security among black breast cancer survivors in Maryland: insights from an online pilot study
PurposeFood security, and reliable access to nutritious food, is essential for maintaining health yet remains elusive for many, including U.S....
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Unravelling heterogeneous malaria transmission dynamics in the Peruvian Amazon: insights from a cross-sectional survey
BackgroundMalaria remains a global health challenge, particularly in Peru's Loreto region. Despite ongoing efforts, high infection rates and...