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  1. Comparison of DNA damage in fresh and frozen blood samples: implications for the comet assay in human biomonitoring studies

    The use of the comet assay in large biomonitoring studies may present logistical and technical challenges because of the processing of numerous...

    Katarina Matković, Marko Gerić, ... Goran Gajski in Archives of Toxicology
    Article 14 July 2024
  2. Synthesis and in vitro assessment of the reactivation profile of clinically available oximes on the acetylcholinesterase model inhibited by A-230 nerve agent surrogate

    The risk of the use of toxic chemicals for unlawful acts has been a matter of concern for different governments and multilateral agencies. The...

    Leandro B. Bernardo, Caio V. N. Borges, ... Daniel A. S. Kitagawa in Archives of Toxicology
    Article 14 July 2024
  3. A multi-biomarker micronucleus assay using imaging flow cytometry

    Genetic toxicity testing assesses the potential of compounds to cause DNA damage. There are many genetic toxicology screening assays designed to...

    Danielle S. G. Harte, Anthony M. Lynch, ... George E. Johnson in Archives of Toxicology
    Article Open access 12 July 2024
  4. A genetic variant in the TAPBP gene enhances cervical cancer susceptibility by increasing m6A modification

    Genetic variants can affect gene expression by altering the level of N6-methyladenosine (m 6 A) modifications. A better understanding of the...

    **g Hu, Shizhi Wang, ... Hua ** in Archives of Toxicology
    Article 12 July 2024
  5. Influence of sustained mild dehydration on thermoregulatory and cognitive functions during prolonged moderate exercise

    Purpose

    The current study investigated whether sustained mild dehydration affects thermoregulatory function and cognitive performance during prolonged...

    Hironori Watanabe, Yuma Kadokura, ... Kei Nagashima in European Journal of Applied Physiology
    Article Open access 10 July 2024
  6. Targeting ferroptosis by natural products in pathophysiological conditions

    Ferroptosis is a form of cell death that is induced by iron-mediated accumulation of lipid peroxidation. The involvement of ferroptosis in different...

    Daheng Zheng, Shikai **, ... **n **e in Archives of Toxicology
    Article 10 July 2024
  7. Advancing Understanding of Chemical Exposures and Maternal-child Health Through the U.S. Environmental Influences on Child Health Outcomes (ECHO) Program: A Sco** Review

    Purpose of Review

    Environmental chemical exposures may disrupt child development, with long-lasting health impacts. To date, U.S. studies of early...

    Emily S. Barrett, Jennifer L. Ames, ... Jonathan Slaughter in Current Environmental Health Reports
    Article Open access 10 July 2024
  8. A modified step–ramp–step protocol to prescribe constant-speed exercise in treadmill running

    Purpose

    This study investigated whether a running-adapted version of the cycling-based “step–ramp–step” (SRS) protocol would improve prediction of ...

    Robin Faricier, Lorenzo Micheli, ... Daniel A. Keir in European Journal of Applied Physiology
    Article 09 July 2024
  9. Integrative effects of resistance training and endurance training on mitochondrial remodeling in skeletal muscle

    Resistance training activates mammalian target of rapamycin (mTOR) pathway of hypertrophy for strength gain, while endurance training increases...

    Yong-Cai Zhao, Bing-hong Gao in European Journal of Applied Physiology
    Article 09 July 2024
  10. Polarized running training adapted to versus contrary to the menstrual cycle phases has similar effects on endurance performance and cardiovascular parameters

    Purpose

    This study compared the effects of polarized running training adapted to the menstrual cycle (MC) phases versus polarized training adapted...

    Claudia Kubica, Sascha Ketelhut, Claudio Renato Nigg in European Journal of Applied Physiology
    Article Open access 08 July 2024
  11. Atorvastatin exerts a preventive effect against steroid-induced necrosis of the femoral head by modulating Wnt5a release

    Steroid-induced osteonecrosis of the femoral head (SONFH) is a prevalent form of osteonecrosis in young individuals. More efficacious clinical...

    Junfeng Wu, Tao Chen, ... Chenxi Gu in Archives of Toxicology
    Article 07 July 2024
  12. Tear Fluid as a Matrix for Biomonitoring Environmental and Chemical Exposures

    Purpose

    Exposures to hazardous chemicals have been linked to many detrimental health effects and it is therefore critical to have effective...

    Parshawn Amini, Joseph O. Okeme in Current Environmental Health Reports
    Article 05 July 2024
  13. Machine learning predicts peak oxygen uptake and peak power output for customizing cardiopulmonary exercise testing using non-exercise features

    Purpose

    Cardiopulmonary exercise testing (CPET) is considered the gold standard for assessing cardiorespiratory fitness. To ensure consistent...

    Charlotte Wenzel, Thomas Liebig, ... Philipp Zimmer in European Journal of Applied Physiology
    Article Open access 03 July 2024
  14. Does a postmortem redistribution affect the concentrations of the 7 azaindole-derived synthetic cannabinoid 5F-MDMB-P7AICA in tissues and body fluids following pulmonary administration to pigs?

    Many fatal intoxications have been reported in connection with the consumption of newer, highly potent synthetic cannabinoids. Yet, a possible...

    Adrian A. Doerr, Frederike Nordmeier, ... Nadine Schaefer in Archives of Toxicology
    Article Open access 02 July 2024
  15. In vitro screening of understudied PFAS with a focus on lipid metabolism disruption

    Per- and polyfluoroalkyl substances (PFAS) are man-made chemicals used in many industrial applications. Exposure to PFAS is associated with several...

    Lackson Kashobwe, Faezeh Sadrabadi, ... Timo Hamers in Archives of Toxicology
    Article Open access 02 July 2024
  16. Exploring the biomechanics and fatigue patterns of eccentric quasi-isometric muscle actions in the knee extensors and flexors

    Purpose

    Eccentric quasi-isometric (EQI) resistance training is emerging as a promising option in sports medicine and rehabilitation. Despite prior...

    Urška Ličen, Dustin J. Oranchuk, Žiga Kozinc in European Journal of Applied Physiology
    Article 02 July 2024
  17. Identification of phase-I and phase-II metabolites and the metabolic pathway of the novel synthetic cannabinoid 5F-EDMB-PICA in vitro

    5F-EDMB-PICA is a newly emerged synthetic cannabinoid which has been characterized in relevant literature in recent years. Although phase-I...

    Yujie Gao, Kaiting Shi, ... Linchuan Liao in Archives of Toxicology
    Article 02 July 2024
  18. Characterizing lipid constituents of B. moojeni snake venom: a comparative approach for chemical and biological investigations

    Snake venoms are complex mixtures majorly composed of proteins with well-studied biological effects. However, the exploration of non-protein...

    Nathalia Santos Carvalho, Viviani Nardini, ... Lúcia Helena Faccioli in Archives of Toxicology
    Article 01 July 2024
  19. Relationship of peak capillary blood lactate accumulation and body composition in determining the mechanical energy equivalent of lactate during sprint cycling

    Aim

    A 15-s all-out sprint cycle test (i.e., νLa max -test) and the post-exercise change in capillary blood lactate concentration is an emerging...

    Benedikt Johannes Meixner, Valentin Nusser, ... Billy Sperlich in European Journal of Applied Physiology
    Article Open access 01 July 2024
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