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  1. No Access

    Article

    Colorectal cancer liver metastasis: genomic evolution and crosstalk with the liver microenvironment

    Colorectal cancer (CRC) patients frequently develop liver metastases, which are the major cause of cancer-related mortality. The molecular basis and management of colorectal liver metastases (CRLMs) remain a c...

    Qiu-Luo Liu, Huijie Zhou, Zong-Guang Zhou, Hai-Ning Chen in Cancer and Metastasis Reviews (2023)

  2. Article

    Open Access

    The long-term survival outcomes of gastric cancer patients with total intravenous anesthesia or inhalation anesthesia: a single-center retrospective cohort study

    The relationship between the type of anesthesia and the survival outcomes of gastric cancer patients is uncertain. This study compared the overall outcome of gastric cancer patients after surgery with total in...

    Wei-Wei Wu, Wei-Han Zhang, Wei-Yi Zhang, Kai Liu, **n-Zu Chen… in BMC Cancer (2021)

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  3. No Access

    Article

    Quantitative comparisons of summary receiver operating characteristics (sROC) curves among conventional serological tumor biomarkers for predicting gastric cancer in Chinese population

    The objective of this study is to quantitatively analyze the predictive strength among the conventional serological tumor biomarkers for gastric cancer in Chinese population. Thirty-three hospital-based case-c...

    **n-Zu Chen, Wei-Han Zhang, Kun Yang, Bo Zhang, Zhi-**n Chen… in Tumor Biology (2014)

  4. No Access

    Article

    Serum miR-21 and miR-92a as biomarkers in the diagnosis and prognosis of colorectal cancer

    Previous studies from our laboratory identified a number of miRNAs that were aberrantly expressed in colorectal cancer (CRC) tissue. However, their diagnostic and prognostic value in serum has not been fully e...

    Guang-Hui Liu, Zong-Guang Zhou, Rong Chen, Mon-** Wang, Bin zhou, Yuan Li… in Tumor Biology (2013)

  5. No Access

    Article

    Chaiqin Chengqi Decoction decreases IL-6 levels in patients with acute pancreatitis

    In this paper, we investigated the effect of the traditional Chinese medicine Chaiqin Chengqi Decoction (CQCQD) on serum cytokines in acute pancreatitis (AP) patients.

    Ling Wang, Yuan Li, Qin Ma, Yong Liu… in Journal of Zhejiang University SCIENCE B (2011)

  6. Article

    Open Access

    Suppression of microRNA-31 increases sensitivity to 5-FU at an early stage, and affects cell migration and invasion in HCT-116 colon cancer cells

    MicroRNAs (miRNAs) are endogenously expressed noncoding RNAs with important biological and pathological functions. Although several studies have shown that microRNA-31 (miR-31) is obviously up-regulated in col...

    Chao-Jie Wang, Johannes Stratmann, Zong-Guang Zhou, **ao-Feng Sun in BMC Cancer (2010)

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  7. No Access

    Article

    Potential role of the TLR4/IRAK-4 signaling pathway in the pathophysiology of acute pancreatitis in mice

    Toll-like receptor 4 (TLR4) is potentially associated with acute pancreatitis (AP), but its exact role remains controversial. IL-1 receptor-associated kinase 4 (IRAK-4) is a common mediator of Toll-like recept...

    Jun-Li Ding, Yuan Li, **ang-Yu Zhou, Ling Wang, Bin Zhou… in Inflammation Research (2009)