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  1. Article

    Open Access

    Early intervention of fractional carbon dioxide laser on fresh traumatic scar

    To determine the combined therapeutic effect of fractional carbon dioxide laser and silicone gel on fresh traumatic scars using a rabbit ear hypertrophic scar (EHS) model, as well as on human subjects. The rab...

    ZiZheng Yang, Yang Lv, Feng Yue, DongSheng Cao in Lasers in Medical Science (2019)

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    Article

    Concentration-Dependent Inhibition of Hypertrophic Scar Formation by Botulinum Toxin Type A in a Rabbit Ear Model

    Hypertrophic scar (HS), as a disappointing result of wound healing, adversely affects the patient, both physically and psychologically. Botulinum toxin type A (BTXA) has been revealed to prevent and improve HS...

    Zhiguo Yang, Yang Lv, Zizheng Yang, Liuliu Cao, Dongsheng Cao in Aesthetic Plastic Surgery (2022)

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    Article

    Early intervention of carbon dioxide fractional laser in hypertrophic scar through TGFβ-1/ Smad3 signaling pathway

    Hypertrophic scars are usually the result of surgical trauma or burn,and more common in individuals with a darker skin color. They appear as red and raised lesions around the wound that continually expand over...

    Zizheng Yang, Zhiguo Yang, Zongbao Zuo in Lasers in Medical Science (2024)