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    Article

    A knowledge-based method to predict the cooperative relationship between transcription factors

    Identifying the cooperation between transcription factors is crucial and challenging to uncover the mystery behind the complex gene expression patterns. Computational methods aimed to infer transcription facto...

    Lingyi Lu, Ziliang Qian, **aoHe Shi, Haipeng Li, Yu-Dong Cai in Molecular Diversity (2010)

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    Predicting miRNA’s target from primary structure by the nearest neighbor algorithm

    We used a machine learning method, the nearest neighbor algorithm (NNA), to learn the relationship between miRNAs and their target proteins, generating a predictor which can then judge whether a new miRNA-targ...

    Kao Lin, Ziliang Qian, Lin Lu, Lingyi Lu, Lihui Lai, Jieyi Gu in Molecular Diversity (2010)

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    Article

    Prediction of compounds’ biological function (metabolic pathways) based on functional group composition

    Efficient in silico screening approaches may provide valuable hints on biological functions of the compound-candidates, which could help to screen functional compounds either in basic researches on metabolic p...

    Yu-Dong Cai, Ziliang Qian, Lin Lu, Kai-Yan Feng, **n Meng, Bing Niu in Molecular Diversity (2008)