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  1. Article

    Open Access

    Electrical coupling regulates layer 1 interneuron microcircuit formation in the neocortex

    The coexistence of electrical and chemical synapses among interneurons is essential for interneuron function in the neocortex. However, it remains largely unclear whether electrical coupling between interneuro...

    **ng-Hua Yao, Min Wang, **ang-Nan He, Fei He, Shu-Qing Zhang… in Nature Communications (2016)

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  2. Article

    Open Access

    Reciprocal regulation of autism-related genes MeCP2 and PTEN via microRNAs

    MeCP2 encodes a methyl-CpG-binding protein that plays a critical role in repressing gene expression, mutations of which lead to Rett syndrome and autism. PTEN is a critical tumor suppressor gene that is frequentl...

    **g-Wen Lyu, Bo Yuan, Tian-Lin Cheng, Zi-Long Qiu, Wen-Hao Zhou in Scientific Reports (2016)

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    Article

    Conditional deletion of Mecp2 in parvalbumin-expressing GABAergic cells results in the absence of critical period plasticity

    Mutations in the X-linked gene encoding the transcriptional modulator methyl–CpG-binding protein 2 (MeCP2) impair postnatal development of the brain. Here we use neuronal-type specific gene deletion in mice to...

    Ling-jie He, Nan Liu, Tian-lin Cheng, **ao-**g Chen, Yi-ding Li… in Nature Communications (2014)