10,397 Result(s)

Article

Dissecting the vascular-cognitive nexus: energetic vs. conventional hemodynamic parameters

Blood pressure or flow measurements have been associated with vascular health and cognitive function. We proposed that energetic hemodynamic parameters may provide a more nuanced understanding and stronger cor...

Hao-Min Cheng, Jiun-Jr Wang, Shao-Yuan Chuang, Chen-Hua Lin… in Hypertension Research (2024)

Article

Correction: Qualitative and quantitative assessment of non-clear cell renal cell carcinoma using contrast-enhanced ultrasound

Wei** Zhang, **gLing Wang, Li Chen, Jiayu Shi in BMC Urology (2024)

Article

Analysis of tumor abnormal protein expression and epidermal growth factor receptor mutation status in non-small cell lung cancer

The level of tumor abnormal protein (TAP) level has a significant impact on tumor growth, recurrence, and metastasis. Previous studies have highlighted the influence of the mutations in exons 19 and 21 of the ...

Yuanjun Cheng, Bin Chen, Qianru Fang, Guohui Zang, Jie Yao in Discover Oncology (2024)

Article

Safety and efficacy of tract embolization using gelatin sponge particles in reducing pneumothorax after CT-guided percutaneous lung biopsy in patients with emphysema

The incidence of pneumothorax is higher in patients with emphysema who undergo percutaneous lung biopsy. Needle embolization has been shown to reduce the incidence of pneumothorax in patients with emphysema. E...

**ong Yang, Hong-Tao Cheng, Yue Huang, Yuan Guo, Hang Yuan… in BMC Pulmonary Medicine (2024)

Article

Methylprednisolone Modulates the Tfr/Tfh ratio in EAE-Induced Neuroinflammation through the PI3K/AKT/FoxO1 and PI3K/AKT/mTOR Signalling Pathways

Methylprednisolone (MP) is a potent glucocorticoid that can effectively inhibit immune system inflammation and brain tissue damage in Multiple sclerosis (MS) patients. T follicular helper (Tfh) cells are a sub...

Nan Wu, Yun Zhao, Minjun **ao, Hui Liu, Hongliang Chen, Bin Liu… in Inflammation (2024)

Article

Incidence of metabolic syndrome in patients with unilateral or bilateral staghorn renal stones and its impact on percutaneous nephrolithotomy outcomes

To evaluate the incidence of metabolic syndrome (MetS) in patients with unilateral and bilateral staghorn calculi (SC) and evaluate the impact on the outcome of percutaneous nephrolithotomy (PCNL).

Zhonghua Shen, Linguo **e, Di Luo, Haijie **e, Hongyang Chen, Chunyu Liu in BMC Urology (2024)

Article

Multi-omics differences in the bone marrow between essential thrombocythemia and prefibrotic primary myelofibrosis

Essential thrombocythemia (ET) and prefibrotic primary myelofibrosis (pre-PMF) are Philadelphia chromosome-negative myeloproliferative neoplasms. These conditions share overlap** clinical presentations; howe...

Anqi Zhang, Ting Sun, Dandan Yu, Rongfeng Fu… in Clinical and Experimental Medicine (2024)

Article

Pituitary-adrenal axis dysfunction induced by tislelizumab immunotherapy for non-small cell lung cancer: a case series and literature review

Adverse events of secondary adrenal insufficiency caused by anti-PD-1 immune agents are relatively rare in clinical practice, so in this article, we retrospectively analyzed three patients who suffered seconda...

Jiayi Wang, Huanrong Lan, **aowei Mao, Yefeng Chen in BMC Pulmonary Medicine (2024)

Article

A deep learning-driven discovery of berberine derivatives as novel antibacterial against multidrug-resistant Helicobacter pylori

Helicobacter pylori (H. pylori) is currently recognized as the primary carcinogenic pathogen associated with gastric tumorigenesis, and its high prevalence and resistance make it difficult to tackle. A graph neur...

**xi Guo, **aosa Zhao, ** Lu, Li** Zhao… in Signal Transduction and Targeted Therapy (2024)

Article

FERMT1 suppression induces anti-tumor effects and reduces stemness in glioma cancer cells

Glioma is a leading cause of mortality worldwide, its recurrence poses a major challenge in achieving effective treatment outcomes. Cancer stem cells (CSCs) have emerged as key contributors to tumor relapse an...

Zhigang Pan, Chuhan Ke, Hanlin Zheng… in Journal of Cancer Research and Clinical On… (2024)

Article

A cellular senescence-related signature for predicting prognosis, immunotherapy response, and candidate drugs in patients treated with transarterial chemoembolization (TACE)

Cellular senescence is essential to TME development, progression, and remodeling. Few studies have examined cellular senescence in HCC after TACE. Investigating the relationship between cellular senescence, po...

Ning He, Wen**g Zhao, Wenlong Tian, Ying Wu, Jian Xu, Yunyan Lu… in Discover Oncology (2024)

Article

Impact of non-emergency surgical timing on postoperative recovery quality in mild or asymptomatic SARS-CoV-2 infected patients: a grouped cohort study

To explore the relationship between the timing of non-emergency surgery in mild or asymptomatic SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infected individuals and the quality of postoperativ...

Qiu-Bo Wang, Yu-Long Wang, Yue-Feng Wang, Hua Chen, Wei Chen… in BMC Anesthesiology (2024)

Article

Analyzing the correlation between low proportion of hobnail features in papillary thyroid carcinoma and clinical aggressiveness risk

Hobnail features may enhance the clinical aggressiveness of papillary thyroid carcinoma (PTC). However, whether a low proportion (<30%) of these features contributes to increased PTC aggressiveness remains unc...

Wen-Shun Liu, Yan-Ting Duan, Guo-Qing Ru, Wan-Yuan Chen, Yuan Chen, Tian Lv… in Endocrine (2024)

Article

Comparison of remimazolam tosilate and propofol during induction and maintenance of general anesthesia in patients undergoing laparoscopic cholecystectomy: a prospective, single center, randomized controlled trial

Remimazolam tosilate (RT) is a new, ultrashort-acting benzodiazepine. Here, we investigated the efficacy and safety of RT for general anesthesia in patients undergoing Laparoscopic Cholecystectomy (LC).

Zhuxin Luo, Hai Cao, Li Luo, Long Chen, Dian Feng, Guihua Huang in BMC Anesthesiology (2024)

Article

Homoharringtonine may help improve the outcomes of venetoclax and azacitidine in AML1-ETO positive acute myeloid leukemia

T(8;21)(q22;q22.1)/AML1-ETO positive acute myeloid leukemia (AE-AML) is sensitive to conventional chemotherapy with a favorable prognosis. However, recent small case reports suggest the limited effectiveness o...

Zhao Yin, Zurong Yao, Dandan Chen, Yu Zhang… in Journal of Cancer Research and Clinical On… (2024)

Article

UBQLN4 promotes the proliferation and invasion of non-small cell lung cancer cell by regulating PI3K/AKT pathway

Ubiquilin-4 (UBQLN4), a member of the ubiquilin family, has received limited attention in cancer research to date. Here, we investigated for the first time the functional role and mechanism of UBQLN4 in non-sm...

Li He, Heng Chen, Bin Ruan, Li He, Ming Luo… in Journal of Cancer Research and Clinical On… (2024)

Article

Obesity, abdominal obesity, metabolic obesity phenotypes, and Helicobacter pylori infection: results from NHANES 1999–2000

Recent studies on the association between Helicobacter pylori (H. pylori) infection and obesity have reported conflicting results. Therefore, the purpose of our study was to investigate the association of obesity...

Danni Chen, Shiling Wang, Wei Yang, Hong Lu, Qian Ren in BMC Infectious Diseases (2024)

Article

Deciphering glutamine metabolism patterns for malignancy and tumor microenvironment in clear cell renal cell carcinoma

Clear cell renal cell carcinoma (ccRCC) is the most common subtype of kidney cancer characterized by metabolic reprogramming. Glutamine metabolism is pivotal in metabolic reprogramming, contributing to the sig...

Gengrun Wu, Teng Li, Yuanbiao Chen, Shiqi Ye… in Clinical and Experimental Medicine (2024)

Article

Nasopharyngeal amyloidoma: report of three cases and review of the literature

Nasopharyngeal amyloidoma is a rare, locally aggressive tumor that has been reported in the English literature in only 38 cases to date, most of which were in the form of case reports. The present study was ai...

Wangsheng Zuo, Yu Du, Jian-ning Chen in Journal of Cancer Research and Clinical Oncology (2024)

Article

Analytical and clinical performance evaluation of a new NT-proBNP assay

The study evaluated the performance of the Mindray N-terminal pro-B-type natriuretic peptide (NT-proBNP) in a healthy population in China, focusing on creating a reference range for future clinical application...

**feng Feng, Junlong Qin, Zhixin Chai, Yajie Zhang… in BMC Cardiovascular Disorders (2024)