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  1. No Access

    Article

    The clinical observation of combined chemotherapy of irinotecan and cisplatin in the treatment of relapsed advanced small cell lung cancer

    To evaluate the efficacy and safety of the irinotecan and cisplatin combination in relapsed advanced small cell lung cancer (SCLC).

    Zhonghai Ren, Chenghui Zhang, Ming Li in The Chinese-German Journal of Clinical Oncology (2008)

  2. No Access

    Article

    A preliminary study on K-ras, EGFR, and B-raf mutations of esophageal squamous cell carcinoma

    Molecular targeted drugs have been widely used in clinical application which has successfully prolonged some patients’ life. Meanwhile, molecular targeted drug therapy for esophageal cancer are attracting more...

    Huili Ma, Yongfei Xue, Changsheng Li in The Chinese-German Journal of Clinical Onc… (2011)

  3. No Access

    Article

    Genome-wide analysis of the WD-repeat protein family in cucumber and Arabidopsis

    The WD-repeat (WDR) proteins comprise an astonishingly diverse superfamily of regulatory proteins. To date, genome-wide characterization of this family has only been conducted in Arabidopsis and little is known a...

    Qiang Li, Panpan Zhao, **g Li, Cunjia Zhang, Lina Wang in Molecular Genetics and Genomics (2014)

  4. No Access

    Article

    Genome-wide identification and characterization of R2R3MYB family in Solanum lycopersicum

    The R2R3MYB proteins comprise one of the largest families of transcription factors and play regulatory roles in developmental processes and defense responses in plants. However, there has been relatively littl...

    Panpan Zhao, Qiang Li, **g Li, Lina Wang, Zhonghai Ren in Molecular Genetics and Genomics (2014)

  5. Article

    Open Access

    Low-dose-intensity bevacizumab with weekly irinotecan for platinum- and taxanes-resistant epithelial ovarian cancer

    The purpose of this study was to evaluate the safety and efficacy of low-dose-intensity bevacizumab and weekly irinotecan as salvage treatment for patients with platinum- and taxanes-resistant advanced epithe...

    Ying Liu, Zhonghai Ren, Shuning Xu, Hua Bai in Cancer Chemotherapy and Pharmacology (2015)

  6. No Access

    Article

    A fragment substitution in the promoter of CsHDZIV11/CsGL3 is responsible for fruit spine density in cucumber (Cucumis sativus L.)

    The indel in the promoter of CsHDZIV11 co-segregates with fruit spine density and could be used for molecular breeding in cucumber.

    Haiyang Zhang, Lina Wang, Shuangshuang Zheng in Theoretical and Applied Genetics (2016)

  7. Article

    Open Access

    Transcriptomic analysis of short-fruit 1 (sf1) reveals new insights into the variation of fruit-related traits in Cucumis sativus

    Fruit size is an important quality trait in different market classes of Cucumis sativus L., an economically important vegetable cultivated worldwide, but the genetic and molecular mechanisms that control fruit si...

    Lina Wang, Chenxing Cao, Shuangshuang Zheng, Haiyang Zhang in Scientific Reports (2017)

  8. Article

    Open Access

    Comprehensive analysis of multiprotein bridging factor 1 family genes and SlMBF1c negatively regulate the resistance to Botrytis cinerea in tomato

    Multiprotein bridging factor 1 s (MBF1s) are members of the transcriptional co-activator family that have involved in plant growth, development and stress responses. However, little is known about the Solanum lyc...

    Xu Zhang, Zhixuan Xu, Lichen Chen, Zhonghai Ren in BMC Plant Biology (2019)

  9. No Access

    Article

    Fabrication of UV-resistant and superhydrophobic surface on cotton fabric by functionalized polyethyleneimine/SiO2 via layer-by-layer assembly and dip-coating

    In this research, a water-soluble ultraviolet (UV) absorber (PEI-H) was synthesized by grafting polyethyleneimine (PEI) with 2,4-dihydroxybenzophenone (UV-0). UV-resistant and superhydrophobic coating was fabr...

    Mimi **ong, Zhonghai Ren, Wei** Liu in Cellulose (2019)

  10. Article

    Open Access

    Genome-wide identification and characterization of cucumber bHLH family genes and the functional characterization of CsbHLH041 in NaCl and ABA tolerance in Arabidopsis and cucumber

    The basic/helix-loop-helix (bHLH) transcription factor family exists in all three eukaryotic kingdoms as important participants in biological growth and development. To date, the comprehensive genomic and func...

    Jialin Li, Ting Wang, **g Han, Zhonghai Ren in BMC Plant Biology (2020)

  11. Article

    Open Access

    Localization of quantitative trait loci for cucumber fruit shape by a population of chromosome segment substitution lines

    Cucumber fruit shape, a significant agronomic trait, is controlled by quantitative trait loci (QTLs). Feasibility of chromosome segment substitution lines (CSSLs) is well demonstrated to map QTLs, especially t...

    **angfei Wang, Hao Li, Zhihui Gao, Lina Wang, Zhonghai Ren in Scientific Reports (2020)

  12. Article

    Open Access

    Genome-wide analysis of the WRKY gene family in the cucumber genome and transcriptome-wide identification of WRKY transcription factors that respond to biotic and abiotic stresses

    Cucumber (Cucumis sativus L.) is an economically important vegetable crop species. However, it is susceptible to various abiotic and biotic stresses. WRKY transcription factors play important roles in plant growt...

    Chunhua Chen, Xueqian Chen, **g Han, Wenli Lu, Zhonghai Ren in BMC Plant Biology (2020)

  13. No Access

    Article

    Overexpression of SlMYB75 enhances resistance to Botrytis cinerea and prolongs fruit storage life in tomato

    SlMYB75 increased the accumulation of JA and improved the scavenging of excess H 2 O ...

    Mengyu Liu, Zhen Zhang, Zhixuan Xu, Lina Wang, Chunhua Chen in Plant Cell Reports (2021)

  14. No Access

    Article

    Transcriptome profiling reveals response genes for downy mildew resistance in cucumber

    We discovered a potential defense pathway of cucumber to downy mildew. The signaling that activates the pathways of ROS and lignin accumulation may play an important role in the defense response. Many resistan...

    **nbin Gao, Pei Guo, Zhiyuan Wang, Chunhua Chen, Zhonghai Ren in Planta (2021)

  15. No Access

    Article

    Genome-wide identification and expression analysis of Hsf and Hsp gene families in cucumber (Cucumis sativus L.)

    Heat shock proteins (Hsps) are molecular chaperones that participate in plant growth and development, and in plant responses to environmental stresses, including heat stress, Hsps' expression is monitored and reg...

    Xueqian Chen, Zhiyuan Wang, Rui Tang, Lina Wang, Chunhua Chen in Plant Growth Regulation (2021)

  16. No Access

    Article

    Cucumber CsHsfA2 improves thermotolerance through self-activation and activation of CsHsp70-1

    Heat stress poses a serious threat to crop growth and development, yield, and quality. The function of heat shock factor A2 (HsfA2) to heat tolerance and its regulatory genes, heat shock proteins (Hsps), has been...

    Zhiyuan Wang, Zhonghai Ren in Plant Growth Regulation (2024)