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    Article

    Finotonlimab with chemotherapy in recurrent or metastatic head and neck cancer: a randomized phase 3 trial

    Immunotherapy combined with chemotherapy regimen has been shown to be effective in recurrent or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC). However, due to the small number of patients, its...

    Yuankai Shi, Wei Guo, Wei Wang, Yunteng Wu, Meiyu Fang, **aoming Huang in Nature Medicine (2024)

  2. Article

    Open Access

    Long non-coding RNA NEAT1 mediated RPRD1B stability facilitates fatty acid metabolism and lymph node metastasis via c-Jun/c-Fos/SREBP1 axis in gastric cancer

    Lymph node metastasis is one of most common determinants of the stage and prognosis of gastric cancer (GC). However, the key molecular events and mechanisms mediating lymph node metastasis remain elusive.

    Yongxu Jia, Qian Yan, Yinli Zheng, Lei Li in Journal of Experimental & Clinical Cancer … (2022)

  3. Article

    Open Access

    Circ-SFMBT2 drives the malignant phenotypes of esophageal cancer by the miR-107-dependent regulation of SLC1A5

    Increasing studies focused on the regulatory roles of circular RNAs (circRNAs) in diverse cancers. This study was to evaluate the function and mechanism of circRNA Scm-like with four malignant brain tumor doma...

    Zhiwei Chang, Yang Fu, Yongxu Jia, Ming Gao, Lijie Song in Cancer Cell International (2021)