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  1. Article

    Open Access

    NOS1 inhibits the interferon response of cancer cells by S-nitrosylation of HDAC2

    The dysfunction of type I interferon (IFN) signaling is an important mechanism of immune escape and metastasis in tumors. Increased NOS1 expression has been detected in melanoma, which correlated with dysfunct...

    Pengfei Xu, Shuangyan Ye, Keyi Li in Journal of Experimental & Clinical Cancer … (2019)

  2. Article

    Open Access

    The role of S-nitrosylation of PFKM in regulation of glycolysis in ovarian cancer cells

    One of the malignant transformation hallmarks is metabolism reprogramming, which plays a critical role in the biosynthetic needs of unchecked proliferation, abrogating cell death programs, and immunologic esca...

    Wenwen Gao, Mengqiu Huang, ** Chen, Jian** Chen, Zhiwei Zou in Cell Death & Disease (2021)

  3. Article

    Open Access

    SLC35E1 promotes keratinocyte proliferation in psoriasis by regulating zinc homeostasis

    Keratinocyte hyperproliferation is a key pathogenic factor in psoriasis. However, the mechanisms that regulate keratinocyte hyperproliferation in this condition remain unclear. Here, we found that SLC35E1 was ...

    Tao Huang, Shijun Chen, Ke Ding, Baoqing Zheng, Weiqi Lv in Cell Death & Disease (2023)