155 Result(s)
within
Zhigang **ang
Life Sciences
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Article
Information fusion technology for terahertz spectra and hyperspectral imaging in wood species identification
This paper proposes the use of information fusion technology to identify different wood species by combining spectral and spatial information from hyperspectral images and terahertz (THz) spectra. The study ut...
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Bacillus altitudinis LZP02 improves rice growth by resha** the rhizosphere microbiome
Rhizosphere microorganisms play an important role in promoting plant growth and maintaining soil health. Bacillus altitudinis LZP02 (LZP02) is an efficient plant growth-promoting rhizobacterium that interacts clo...
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5-Aminolevulinic acid regulates the grain morphology, carbohydrate and hormone contents, increasing grain yield of maize in field land
5-aminolaevulinic acid (ALA), being a plant growth promoter, effectively improves plant growth and development. However, relevant reports are deficient on how ALA regulates the maize grain yield. In this study...
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Genome sequence of Leclercia adecarboxylata QDSM01 with multiple plant growth promoting properties
Leclercia adecarboxylata QDSM01 is a plant growth-promoting bacterium isolated from the rhizosphere soil of maize. However, the relevant molecular mechanisms remain obscure. This study investigated the effect of
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Ecological filtering shapes the impacts of agricultural deforestation on biodiversity
The biodiversity impacts of agricultural deforestation vary widely across regions. Previous efforts to explain this variation have focused exclusively on the landscape features and management regimes of agricu...
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Open AccessUtilizing transcriptomics and metabolomics to unravel key genes and metabolites of maize seedlings in response to drought stress
Drought stress can substantially restrict maize growth and productivity, and global warming and an increasing frequency of extreme weather events are likely to result in more yield losses in the future. Theref...
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Open AccessComparative Transcriptome Combined with Morphophysiological Analyses Revealed Carotenoid Biosynthesis for Differential Chilling Tolerance in Two Contrasting Rice (Oryza sativa L.) Genotypes
Early spring cold spells can lead to leaf chlorosis during the rice seedling greening process. However, the physiological and molecular mechanisms underlying the rice greening process under low-temperature con...
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Open AccessKaposi’s sarcoma-associated herpesvirus viral protein kinase augments cell survival
Oncogenic viruses have developed various strategies to antagonize cell death and maintain lifelong persistence in their host, a relationship that may contribute to cancer development. Understanding how viruses...
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Siglec-9 acts as an immune-checkpoint molecule on macrophages in glioblastoma, restricting T-cell priming and immunotherapy response
Neoadjuvant immune-checkpoint blockade therapy only benefits a limited fraction of patients with glioblastoma multiforme (GBM). Thus, targeting other immunomodulators on myeloid cells is an attractive therapeu...
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CASC9 potentiates gemcitabine resistance in pancreatic cancer by reciprocally activating NRF2 and the NF-κB signaling pathway
Gemcitabine resistance is a frequently occurring and intractable obstacle in pancreatic cancer treatment. However, the underlying mechanisms require further investigation. Adaptive regulation of oxidative stre...
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Temporal microbial succession drives phase-dependent kinetics of di(2-ethylhexyl) phthalate biodegradation in soil
Di(2-ethylhexyl) phthalate (DEHP), one of the most important plasticizers, is considered a typical endocrine disruptor. Soil contains high levels of DEHP, and acts as the main medium for its migration into foo...
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Four thermostatic steps: A novel CRISPR-Cas12-based system for the rapid at-home detection of respiratory pathogens
The outbreak of coronavirus disease 2019 (COVID-19) in 2019 has severely damaged the world's economy and public health and made people pay more attention to respiratory infectious diseases. However, traditiona...
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Open AccessTRIM64 promotes ox-LDL-induced foam cell formation, pyroptosis, and inflammation in THP-1-derived macrophages by activating a feedback loop with NF-κB via IκBα ubiquitination
Atherosclerosis is a chronic inflammatory disease and the main pathology behind most cardiovascular diseases and the overactivation of macrophages initiates the development of atherosclerosis. However, the spe...
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Open AccessGut microbiome determines therapeutic effects of OCA on NAFLD by modulating bile acid metabolism
Non-alcoholic fatty liver disease (NAFLD), the most common chronic liver disease, had no approved pharmacological agents yet. Obeticholic acid (OCA), a novel bile acid derivative, was demonstrated to ameliorat...
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Open AccessGut microbiome signatures of extreme environment adaption in Tibetan pig
Tibetan pigs (TPs) can adapt to the extreme environments in the Tibetan plateau implicated by their self-genome signals, but little is known about roles of the gut microbiota in the host adaption. Here, we rec...
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Development of VHL-recruiting STING PROTACs that suppress innate immunity
STING acts as a cytosolic nucleotide sensor to trigger host defense upon viral or bacterial infection. While STING hyperactivation can exert anti-tumor effects by increasing T cell filtrates, in other contexts...
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Loss of the receptors ER, PR and HER2 promotes USP15-dependent stabilization of PARP1 in triple-negative breast cancer
Poly(ADP-ribose) polymerase 1 (PARP1) is essential for the progression of several types of cancers. However, whether and how PARP1 is stabilized to promote genomic stability in triple-negative breast cancer (T...
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Open AccessMenstrual blood-derived endometrial stem cells alleviate neuroinflammation by modulating M1/M2 polarization in cell and rat Parkinson’s disease models
Neuroinflammation is closely related to the development of Parkinson's disease (PD). Because of the extensive sources, non-invasive and periodical collection method, human menstrual blood-derived endometrial s...
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Open AccessInsufficient epitope-specific T cell clones are responsible for impaired cellular immunity to inactivated SARS-CoV-2 vaccine in older adults
Aging is a critical risk factor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine efficacy. The immune responses to inactivated vaccine for older adults, and the underlying mechanisms of...
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Podocyte-specific deletion of ubiquitin carboxyl-terminal hydrolase L1 causes podocyte injury by inducing endoplasmic reticulum stress
Ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) is a unique component of the ubiquitin–proteasome system (UPS), which has multiple activities in maintaining intracellular ubiquitin levels. We previously repor...
