Thyroid FNA Cytology
Differential Diagnoses and Pitfalls
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Residual lymph node metastases (RLNM) remained a great concern in the implementation of organ-preserving strategies and led to poor prognosis in locally advanced rectal cancer (LARC). In this study, we aimed t...
Article
Locally advanced papillary thyroid cancer (LAPTC) has poor prognosis. Large-scale genomic testing has revealed multiple oncogenic drivers which may be essential for understanding tumor progression. However, th...
Article
Data available for pharmacokinetics (PK)/pharmacodynamics (PD) of ticagrelor and significant endogenous/exogenous factors or biomarkers related to bleeding events in both healthy and clinical patients are limi...
Article
Integrins are considered the main cell-adhesion transmembrane receptors that play multifaceted roles as extracellular matrix (ECM)-cytoskeletal linkers and transducers in biochemical and mechanical signals bet...
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Although histological identification of invasion and metastasis are evidence of malignancy in the definition of cancer, most differentiated thyroid carcinomas with those features are indolent, and stable disea...
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A 50-year-old lady presented to the outpatient department with a painless neck swelling that moved on deglutition. Ultrasound examination of the neck revealed a TR5 encapsulated thyroid nodule. Preoperative cy...
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Thyroid tumors are common endocrine disorders, including benign, low risk, and malignant tumors. Ultrasound-guided fine-needle aspiration (FNA) is widely applied as a reliable and minimally invasive technique ...
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Cribriform morular thyroid carcinoma (CM-TC) was a subtype of papillary thyroid carcinoma in the 4th edition WHO classification of thyroid tumor, because part of papillary thyroid carcinoma-type nuclear features ...
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Most Asian pathologists follow international diagnostic systems developed by Western authors, such as the Bethesda system for reporting thyroid cytopathology and the WHO classification of tumors of endocrine o...
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There are significant differences in the diagnostic criteria for papillary thyroid carcinoma (PTC) among pathologists. In Western cytology practice, cases with papillary-like nuclear features (nuclear features...
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Pathologists initiated and promoted the introduction of noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP). An ample amount of knowledge about NIFTP has been contributed by As...
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The fifth edition of the World Health Organization (WHO) classification of thyroid tumors established a new category, “low-risk neoplasm,” which includes borderline tumors (non-invasive follicular thyroid neop...
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Thyroid nodules are common, and the risk of develo** thyroid nodules with clinical symptoms is increasing. It is necessary to distinguish benign nodules from thyroid malignancies, as this can reduce unnecess...
Article
The search for potential gene loci that affect the pharmacodynamics and pharmacokinetics of ticagrelor is a matter of broad clinical interest. The objective of this study was to investigate the effect of genet...
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Studies show inconsistent results regarding the impact of CYP2C19 genotype on the pharmacodynamics (PD) and clinical outcomes of ticagrelor. With the implementation of genotype-guided individualized antiplatelet ...
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Proprotein convertase subtilisin/kexin type 9 (PCSK9) monoclonal antibodies are powerful lipid-lowering drugs which have been shown to improve clinical endpoints in patients with hypercholesterolemia. However,...
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T-cell immunoglobulin and mucin-domain containing-3 (Tim-3), mediating immune exhaustion in tumor microenvironment, has become a promising target for tumor therapy. However, the exact mechanisms for tumor cell...