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  1. No Access

    Chapter

    Consideration of Patients’ Viewpoint and the Role of Pathologists in Reporting Diagnosis of Thyroid Carcinomas

    Although histological identification of invasion and metastasis are evidence of malignancy in the definition of cancer, most differentiated thyroid carcinomas with those features are indolent, and stable disea...

    Naomi Kitayama, Zhiyan Liu, Kennichi Kakudo in Thyroid FNA Cytology (2023)

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    Chapter

    Papillae in Thyroid Aspirates

    A 50-year-old lady presented to the outpatient department with a painless neck swelling that moved on deglutition. Ultrasound examination of the neck revealed a TR5 encapsulated thyroid nodule. Preoperative cy...

    Shipra Agarwal, **n **g, Claire W. Michael, Zhiyan Liu in Thyroid FNA Cytology (2023)

  3. No Access

    Chapter

    Practice of Molecular Detection of Thyroid Fine-Needle Aspiration Specimen in China

    Thyroid tumors are common endocrine disorders, including benign, low risk, and malignant tumors. Ultrasound-guided fine-needle aspiration (FNA) is widely applied as a reliable and minimally invasive technique ...

    Zhiyan Liu, Qiong Jiao, Kennichi Kakudo in Thyroid FNA Cytology (2023)

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    Chapter

    Cribriform-Morular Thyroid Carcinoma

    Cribriform morular thyroid carcinoma (CM-TC) was a subtype of papillary thyroid carcinoma in the 4th edition WHO classification of thyroid tumor, because part of papillary thyroid carcinoma-type nuclear features ...

    Zhiyan Liu, Chunyan Zhang, Qianqian Wang, Ayana Suzuki in Thyroid FNA Cytology (2023)

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    Chapter

    Addressing the Impact of International Variation in Thyroid Cytology: Which Reporting System Is Best for Patients?

    Most Asian pathologists follow international diagnostic systems developed by Western authors, such as the Bethesda system for reporting thyroid cytopathology and the WHO classification of tumors of endocrine o...

    Kennichi Kakudo, Andrey Bychkov, Mitsuyoshi Hirokawa in Thyroid FNA Cytology (2023)

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    Chapter

    Diagnostic Criteria of Papillary Thyroid Carcinoma (PTC)-Type Nuclear Features Impacting Thyroid Fine Needle Aspiration (FNA) Cytology

    There are significant differences in the diagnostic criteria for papillary thyroid carcinoma (PTC) among pathologists. In Western cytology practice, cases with papillary-like nuclear features (nuclear features...

    Kennichi Kakudo, Zhiyan Liu, Andrey Bychkov, Mitsuyoshi Hirokawa in Thyroid FNA Cytology (2023)

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    Book

    Thyroid FNA Cytology

    Differential Diagnoses and Pitfalls

    Kennichi Kakudo, Zhiyan Liu, Chan Kwon Jung (2023)

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    Chapter

    NIFTP in Asian Practice

    Pathologists initiated and promoted the introduction of noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP). An ample amount of knowledge about NIFTP has been contributed by As...

    Andrey Bychkov, Chanchal Rana, Zhiyan Liu, Chan Kwon Jung in Thyroid FNA Cytology (2023)

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    Chapter

    Low-Risk Neoplasms in the Fifth Edition of the WHO Classification of Thyroid Tumors

    The fifth edition of the World Health Organization (WHO) classification of thyroid tumors established a new category, “low-risk neoplasm,” which includes borderline tumors (non-invasive follicular thyroid neop...

    Kennichi Kakudo, Yaqion Li, Yanhua Bai, Zhiyan Liu in Thyroid FNA Cytology (2023)

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    Chapter

    Molecular Classification of Thyroid Tumors and Key Molecular Features to Identify High-Grade Thyroid Carcinomas

    Thyroid nodules are common, and the risk of develo** thyroid nodules with clinical symptoms is increasing. It is necessary to distinguish benign nodules from thyroid malignancies, as this can reduce unnecess...

    Yi Wang, Likun Zhang, Zhiyan Liu in Thyroid FNA Cytology (2023)

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    Article

    Histopathologic Assessment of Capsular Invasion in Follicular Thyroid Neoplasms—an Observer Variation Study

    The assessment of capsular invasion is an essential but challenging step in the diagnosis of encapsulated follicular thyroid neoplasms. Therefore, interobserver agreement in the assessment of capsular invasion...

    Yun Zhu, Yaqiong Li, Chan Kwon Jung, Dong Eun Song, Jen-Fan Hang in Endocrine Pathology (2020)

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    Article

    Efficacy and Safety of PCSK9 Monoclonal Antibodies in Patients at High Cardiovascular Risk: An Updated Systematic Review and Meta-Analysis of 32 Randomized Controlled Trials

    Proprotein convertase subtilisin/kexin type 9 (PCSK9) monoclonal antibodies are powerful lipid-lowering drugs which have been shown to improve clinical endpoints in patients with hypercholesterolemia. However,...

    Guangyan Mu, Qian **ang, Shuang Zhou, Zhiyan Liu, Litong Qi in Advances in Therapy (2020)

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    Chapter

    Hyalinizing Trabecular Tumor of the Thyroid: FNA Samples Using HE Staining

    The cell smear of hyalinizing trabecular tumor was rich in atypical neoplastic cells arranged in a nest and trabecular pattern. The hyaline materials were observed in the center of the clusters and among the d...

    Zhiyan Liu, **aofang Zhang, Peng Su, Yaqiong Li, Kai Liang in Thyroid FNA Cytology (2019)

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    Chapter

    Nuclear Features of Papillary Thyroid Carcinoma (BRAF-Like Tumors), Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (RAS-Like Tumors), and Follicular Adenoma/Follicular Thyroid Carcinoma (RAS-Like Tumors)

    In seminal papers for noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) and the fourth edition WHO classification, NIFTP was defined by the following four features: (1) nonin...

    Kennichi Kakudo, Zhiyan Liu, Andrey Bychkov, Chan Kwon Jung in Thyroid FNA Cytology (2019)

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    Chapter

    Diagnostic Criteria for AUS/FLUS in the Second Edition Bethesda System for Reporting Thyroid Cytopathology

    Although approximately 30% of FNAs result in indeterminate diagnoses, a comprehensive diagnostic approach to thyroid follicular cell tumors was provided by the Bethesda system. When histological type is uncert...

    Kennichi Kakudo, Zhiyan Liu, Yubo Ren, Tomoko Wakasa in Thyroid FNA Cytology (2019)

  16. No Access

    Chapter

    NIFTP in Asian Practice: A Pathologist’s Perspective

    The introduction of noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) was initiated and promoted by pathologists. Recent Asian studies added new knowledge to the existing lit...

    Andrey Bychkov, Chan Kwon Jung, Zhiyan Liu, Kennichi Kakudo in Thyroid FNA Cytology (2019)

  17. Article

    Open Access

    Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features in Asian Practice: Perspectives for Surgical Pathology and Cytopathology

    The introduction of noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) was initiated and promoted by pathologists. Recent Asian studies added new knowledge to the existing lit...

    Andrey Bychkov, Chan Kwon Jung, Zhiyan Liu, Kennichi Kakudo in Endocrine Pathology (2018)