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Article
Endothelial Insulin-Like Growth Factor-1 Modulates Proliferation and Phenotype of Smooth Muscle Cells Induced by Low Shear Stress
Endothelial cells (ECs) are directly exposed to shear stress and modulate the neighboring vascular smooth muscle cells (VSMCs), which plays important roles in vascular remodeling during atherosclerosis. Our pr...
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Article
RACK1 Regulates Src Activity on Apoptosis of Vascular Smooth Muscle Cells Induced by Cyclic Strain
Mechanical cyclic strain (CS) is an important regulator of apoptosis of vascular smooth muscle cells (VSMCs), which are involved in vascular remodeling during hypertension. However, its mechanism is still uncl...
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Article
Spontaneous Rhythmic Inward Currents Recorded in Interstitial Cells of Rabbit Portal Vein
It is now well established that smooth muscle of the portal vein exhibits spontaneous rhythmic contraction in vitro. The present study was designed to investigate the pacemaking mechanism(s) underlying the spo...
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Article
Normal Shear Stress and Vascular Smooth Muscle Cells Modulate Migration of Endothelial Cells Through Histone Deacetylase 6 Activation and Tubulin Acetylation
Endothelial cells (ECs) line the innermost of the blood vessel wall and are constantly subjected to shear stress imposed by blood flow. ECs were also influenced by the neighboring vascular smooth muscle cells ...