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Article
Effects of exogenous GA, IAA, ABA and ethylene on pear (Pyrus pyrifolia) fruit during different development stages
Phytohormones play crucial roles in fruit development and ripening. However, it is unclear the role of phytohormones in pear fruit quality, such as transverse and longitudinal diameters, fruit weight, soluble ...
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Article
Upcycling waste sewage sludge into superior single-atom Fenton-like catalyst for sustainable water purification
The worldwide generation of waste sludge emanating from municipal wastewater treatment plants amounts to 80–90 million tons of dry matter annually and continues to escalate, posing a substantial economic and e...
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Article
Visualization for physics analysis improvement and applications in BESIII
Modern particle physics experiments usually rely on highly complex and large-scale spectrometer devices. In high energy physics experiments, visualization helps detector design, data quality monitoring, offlin...
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Article
Open AccessMyricetin mitigates motor disturbance and decreases neuronal ferroptosis in a rat model of Parkinson’s disease
Ferroptosis is an iron-dependent cell death form characterized by reactive oxygen species (ROS) overgeneration and lipid peroxidation. Myricetin, a flavonoid that exists in numerous plants, exhibits potent ant...
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Article
Preparation of water-soluble tantalum nanoparticles and their radiosensitization application
Radiation therapy (RT) that utilizes high dose of ionizing radiation to kill tumor cells is a common cancer treatment method. However, the effectiveness of RT is limited by the tolerance of normal tissue surro...
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Article
The clinical significance and prognostic value of serum beta-2 microglobulin in adult lymphoma-associated hemophagocytic lymphohistiocytosis: a multicenter analysis of 326 patients
To investigate the prognostic impact of serum beta-2 microglobulin (B2M) in adult lymphoma-associated hemophagocytic lymphohistiocytosis (HLH). The clinical and laboratory characteristics of 326 adult patients...
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Article
Targeted Therapy of Spinal Cord Injury: Inhibition of Apoptosis Is a Promising Therapeutic Strategy
Spinal cord injury (SCI) is a serious disabling central nervous system injury that can lead to motor, sensory, and autonomic dysfunction below the injury level. SCI can be divided into primary injury and secon...
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Article
Open AccessSystem-wide identification of novel de-ubiquitination targets for USP10 in gastric cancer metastasis through multi-omics screening
Ubiquitin-specific peptidase 10 (USP10), a typical de-ubiquitinase, has been found to play a double-edged role in human cancers. Previously, we reported that the expression of USP10 was negatively correlated w...
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Article
Unleashing the Power of Bio-based Thermotropic Liquid Crystal Modifiers: Toughening and Reinforcing Petroleum-based Epoxy Resin without Compromising Other Properties
Toughening the petroleum-based epoxy resin blends with bio-based modifiers without compromising their modulus, mechanical strength, and other properties is still a big challenge in view of the sustainability. ...
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Article
Transplantation of olfactory mucosa mesenchymal stromal cells repairs spinal cord injury by inducing microglial polarization
Animal studies
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Article
Liquid-phase epitaxial layer by layer brushing fabrication of metal-organic frameworks films
Development of metal-organic framework (MOF) films is of great importance to expand their applications. Herein, we report a facile and universal method of liquid-phase epitaxial (LPE) layer by layer (LBL) brus...
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Article
Graphene-anchored sodium single atoms: A highly active and stable catalyst for transesterification reaction
Solid strong base catalysts have received considerable attention in various organic reactions due to their facile separation, neglectable corrosion, and environmental friendliness. Although great progress has ...
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Article
Exploration of anomaly separation technology of wide-field electromagnetic method
To improve the accuracy of data processing and interpretation, effective suppression of the regional background field and extraction of the local anomaly field for further analyses represent urgent issues that...
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Article
Open AccessA multicenter prospective study on the management of hepatoblastoma in children: a report from the Chinese Children’s Cancer Group
This study aimed to identify survival risk factors in Chinese children with hepatoblastoma (HB) and assess the effectiveness of the new treatment protocol proposed by the Chinese Children’s Cancer Group (CCCG)...
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Article
Open AccessIdentification of a pathogenic SMCHD1 variant in a Chinese patient with bosma arhinia microphthalmia syndrome: a case report
Bosma arhinia microphthalmia syndrome (BAMS; MIM603457) is a rare genetic disorder, predominantly autosomal dominant. It is a multi-system developmental disorder characterized by severe hypoplasia of the nose ...
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Article
Open AccessConditional knockdown of OsMLH1 to improve plant prime editing systems without disturbing fertility in rice
High-efficiency prime editing (PE) is desirable for precise genome manipulation. The activity of mammalian PE systems can be largely improved by inhibiting DNA mismatch repair by coexpressing a dominant-negati...
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Article
Open AccessExamining dynamic developmental trends: the interrelationship between age-friendly environments and healthy aging in the Chinese population—evidence from China Health and Retirement Longitudinal Study, 2011–2018
The objective of this research is to investigate the dynamic developmental trends between Age-Friendly Environments (AFE) and healthy aging in the Chinese population.
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Article
Effect of MgO on Phase Structure and Evolution of Steelmaking Slag During Cooling
The underutilization of steelmaking slags is primarily ascribed to instability, predominantly influenced by their intricate phase structure. The presence of MgO, a key constituent in steelmaking slag, contribu...
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Article
Open AccessAn unexpected role of EasDaf: catalyzing the conversion of chanoclavine aldehyde to chanoclavine acid
Ergot alkaloids (EAs) are a diverse group of indole alkaloids known for their complex structures, significant pharmacological effects, and toxicity to plants. The biosynthesis of these compounds begins with ch...
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Article
Open AccessPrediction of blood–brain barrier penetrating peptides based on data augmentation with Augur
The blood–brain barrier serves as a critical interface between the bloodstream and brain tissue, mainly composed of pericytes, neurons, endothelial cells, and tightly connected basal membranes. It plays a pivo...
