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Article
Open AccessPhase separation of RNF214 promotes the progression of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors, and the expression and function of an uncharacterized protein RNF214 in HCC are still unknown. Phase separation has recently been obse...
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Article
Open AccessSyrosingopine and UK5099 synergistically suppress non-small cell lung cancer by activating the integrated stress response
Non-small cell lung cancer (NSCLC) presents a global health challenge due to its low five-year survival rates, underscoring the need for novel therapeutic strategies. Our research explored the synergistic mech...
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Article
Open AccessDevelopment and validation of a nomogram for assessing survival in acute exacerbation of chronic obstructive pulmonary disease patients
Early prediction of survival of hospitalized acute exacerbations of chronic obstructive pulmonary disease (AECOPD) patients is vital. We aimed to establish a nomogram to predict the survival probability of AEC...
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Article
Open AccessClinical diagnosis and treatment of 37 cases of gallbladder neuroendocrine carcinoma
This study aims to investigate the clinical and pathological characteristics, treatment approaches, and prognosis of gallbladder neuroendocrine carcinoma (GB-NEC).
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Article
Open AccessBenefit finding among family caregivers of patients with advanced cancer in a palliative treatment: a qualitative study
Benefit finding is the search for positive meaning from traumatic events, such as cancer. It can help caregivers have a positive experience in the caregiving process, relieve negative emotions, and reduce care...
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Article
Open AccessHydrogen sulfide activates calcium signaling to confer tolerance against selenium stress in Brassica rapa
Se (selenium) pollution is an emerging environmental concern. Excessive Se induces phytotoxicity. The endogenous H2S (hydrogen sulfide) was involved in plant adaptation to Se stress, but the signaling player of H
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Article
Open AccessDevelopment and application of a colloidal-gold immunochromatographic strip for detecting Getah virus antibodies
Getah virus (GETV) is a re-emerging mosquito-borne alphavirus that is highly pathogenic, mainly to pigs and horses. There are no vaccines or treatments available for GETV in swine in China. Therefore, the deve...
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Article
Open AccessSurgical intervention of Lemierre’s syndrome: a case report and review of the literature
Lemierre’s syndrome is a fatal and rare disease that is typically characterized by oropharyngeal infection and internal jugular vein thrombosis. Timely institution of appropriate antibiotics is the standard tr...
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Article
Open AccessLAMP2A regulates cisplatin resistance in colorectal cancer through mediating autophagy
Drug resistance is an important constraint on clinical outcomes in advanced cancers. LAMP2A is a limiting protein in molecular chaperone-mediated autophagy. This study was aimed to explore LAMP2A function in c...
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Article
Open AccessSexual experience in patients with coronary heart disease: a descriptive phenomenological study
Sex is an essential part of life and is a basic demand for human beings. Coronary heart disease can have an impact on patients’ sexual lives; however, not much attention has been paid to it in China, and few s...
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Article
Open AccessCollapse of carbon nanotubes due to local high-pressure from van der Waals encapsulation
Van der Waals (vdW) assembly of low-dimensional materials has proven the capability of creating structures with on-demand properties. It is predicted that the vdW encapsulation can induce a local high-pressure...
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Article
Open AccessOnline Learner Categories Recognition Based on MoE-LSTM Model
Online learner behaviour patterns are comprehensive indicators reflecting the learning status and learning outcomes of online learners, which have a guiding role in the design, implementation and improvement o...
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Article
Open AccessVectorized dataset of silted land formed by check dams on the Chinese Loess Plateau
Check dams on the Chinese Loess Plateau (CLP) have captured billions of tons of eroded sediment, substantially reducing sediment load in the Yellow River. However, uncertainties persist regarding the precise s...
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Article
Open AccessThe LRR receptor-like kinase ALR1 is a plant aluminum ion sensor
Plant survival requires an ability to adapt to differing concentrations of nutrient and toxic soil ions, yet ion sensors and associated signaling pathways are mostly unknown. Aluminum (Al) ions are highly phyt...
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Article
Open AccessFerroelectric compute-in-memory annealer for combinatorial optimization problems
Computationally hard combinatorial optimization problems (COPs) are ubiquitous in many applications. Various digital annealers, dynamical Ising machines, and quantum/photonic systems have been developed for so...
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Article
Open AccessDual inhibitors of DNMT and HDAC induce viral mimicry to induce antitumour immunity in breast cancer
The existing conventional treatments for breast cancer, including immune checkpoint blockade, exhibit limited effects in some cancers, particularly triple-negative breast cancer. Epigenetic alterations, specif...
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Article
Open AccessMediating effect of psychological capital on the relationship between mental health literacy and co** styles among newly recruited nurses
Newly recruited nurses face multiple sources of stress and their co** styles need to be focused on to ensure good mental health. This study aimed to examine the relationship among mental health literacy, psy...
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Article
Open AccessAssociation between elevated serum matrix metalloproteinase-2 and tumor necrosis factor-α, and clinical symptoms in male patients with treatment-resistant and chronic medicated schizophrenia
Inflammation has an important role in the pathogenesis of schizophrenia. The aim of this study was to investigate the levels of tumor necrosis factor (TNF) and matrix metalloproteinase-2 (MMP-2) in male patien...
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Article
Open AccessCurrent trends and future directions of global research on wastewater to energy: a bibliometric analysis and review
This paper presents a structured bibliometric analysis and review of the research publications recorded in the Web of Science database from 2000 to 2023 to methodically examine the landscape and development of...
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Article
Open AccessElectron/infrared-phonon coupling in ABC trilayer graphene
Stacking order plays a crucial role in determining the crystal symmetry and has significant impacts on electronic, optical, magnetic, and topological properties. Electron-phonon coupling, which is central to a...
