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Brain-Targeting Emodin Mitigates Ischemic Stroke via Inhibiting AQP4-Mediated Swelling and Neuroinflammation

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  1. Article

    Open Access

    Effect of pericapsular nerve group block and suprainguinal fascia iliaca block on postoperative analgesia and stress response in elderly patients undergoing hip arthroplasty: a prospective randomized controlled double-blind trial

    As a novel regional analgesic technique, ultrasound-guided pericapsular nerve group (PENG) block has some potential advantages, and we designed a randomized clinical trial (RCT) to investigate whether the ultr...

    **aozhen Cui, Zhi Cheng, Tianyu Zhang, Hai Xu, Hengfei Luan in BMC Anesthesiology (2024)

  2. Article

    Open Access

    Development and validation of an intraoperative hypothermia nomograph model for patients undergoing video-assisted thoracoscopic lobectomy: a retrospective study

    This study aimed to develop and internally validate a nomogram model for assessing the risk of intraoperative hypothermia in patients undergoing video-assisted thoracoscopic (VATS) lobectomy. This study is a r...

    Fuhai **a, Qiang Li, Liqin Xu, ** Chen, Gen Li, Li Li, Zhineng Cheng in Scientific Reports (2024)

  3. Article

    Open Access

    Numerical modeling on wave–current flows and bed shear stresses over an algal reef

    Currents in coastal zones under multiple mechanisms in terms of tides, waves, wind, and high roughness are difficult to model; bed shear stresses under wave–current flows are particularly challenging yet not b...

    Yi-Ru Lan, Zhi-Cheng Huang in Environmental Fluid Mechanics (2024)

  4. Article

    Open Access

    Three-dimensional finite element analysis of the optimal mechanical design for maximum inward movement of the anterior teeth with clear aligners

    This study aims to refine clinical designs within clear aligner therapy, exploring the appropriate ratio of anterior tooth retraction to intrusion under maximum anchorage. Using a three-dimensional finite elem...

    **gcheng Chen, Daoyu Zhu, Mengli Zhao, Zhiheng Cheng, Yan Pan in Scientific Reports (2024)

  5. Article

    Open Access

    Carotenoid biosynthesis genes LcLCYB, LcLCYE, and LcBCH from wolfberry confer increased carotenoid content and improved salt tolerance in tobacco

    Carotenoids play essential roles in plant growth and development and provide plants with a tolerance to a series of abiotic stresses. In this study, the function and biological significance of lycopene β-cycla...

    Chen Li, Caili Wang, Zhiyang Cheng, Yu Li, Wen**g Li in Scientific Reports (2024)

  6. Article

    Open Access

    Specific convulsions and brain damage in children hospitalized for Omicron BA.5 infection: an observational study using two cohorts

    SARS-CoV-2 continues to mutate over time, and reports on children infected with Omicron BA.5 are limited. We aimed to analyze the specific symptoms of Omicron-infected children and to improve patient care.

    Yuan-Yuan Pei, Hong-Li Wang, Gen-Quan Yin, Yi Xu in World Journal of Pediatrics (2024)

  7. Article

    Open Access

    Chromosome-level genome assembly of the bethylid ectoparasitoid wasp Sclerodermus sp. ‘alternatusi’

    The Bethylidae are the most diverse of Hymenoptera chrysidoid families. As external parasitoids, the bethylids have been widely adopted as biocontrol agents to control insect pests worldwide. Thus far, the gen...

    Yi Wan, Hui-Jie Wu, Jia-Peng Yang, **-Li Zhang, Zhi-Cheng Shen in Scientific Data (2024)

  8. Article

    Open Access

    Associations between trans fatty acids and systemic immune-inflammation index: a cross-sectional study

    Previous studies have demonstrated that trans fatty acids (TFAs) intake was linked to an increased risk of chronic diseases. As a novel systemic inflammatory biomarker, the clinical value and efficacy of the s...

    **ao-Feng Zhu, Yu-Qi Hu, Zhi-Cheng Dai, **u-Juan Li in Lipids in Health and Disease (2024)

  9. Article

    Open Access

    Measuring Chinese mobility behaviour during COVID-19 using geotagged social media data

    COVID-19 caused widespread disruption to normal lives and human activities. In China, the mobility behaviour response to the COVID-19 pandemic at the intra-city and population group levels is largely unknown, ...

    Kaixin Zhu, Zhifeng Cheng, Jianghao Wang in Humanities and Social Sciences Communications (2024)

  10. Article

    Open Access

    Fast pseudorandom quantum state generators via inflationary quantum gates

    We propose a mechanism for reaching pseudorandom quantum states, computationally indistinguishable from Haar random, with shallow log-n depth quantum circuits, where n is the number of qudits. We argue that ...

    Claudio Chamon, Eduardo R. Mucciolo, Andrei E. Ruckenstein in npj Quantum Information (2024)

  11. Article

    Open Access

    Hopf bifurcation in an age-structured predator–prey system with Beddington–DeAngelis functional response and constant harvesting

    In this paper, an age-structured predator–prey system with Beddington–DeAngelis (B–D) type functional response, prey refuge and harvesting is investigated, where the predator fertility function f(a) and the matur...

    San-**ng Wu, Zhi-Cheng Wang, Shigui Ruan in Journal of Mathematical Biology (2024)

  12. Article

    Open Access

    Catalytic polymer self-cleavage for CO2 generation before combustion empowers materials with fire safety

    Polymeric materials, rich in carbon, hydrogen, and oxygen elements, present substantial fire hazards to both human life and property due to their intrinsic flammability. Overcoming this challenge in the absenc...

    Wei Luo, Ming-Jun Chen, Ting Wang, **-Feng Feng, Zhi-Cheng Fu in Nature Communications (2024)

  13. Article

    Open Access

    Does a new case-based payment system promote the construction of the ordered health delivery system? Evidence from a pilot city in China

    The construction of the ordered health delivery system in China aims to enhance equity and optimize the efficient use of medical resources by rationally allocating patients to different levels of medical insti...

    Huanyu Shi, Zhichao Cheng, Zhichao Liu in International Journal for Equity in Health (2024)

  14. Article

    Correction: Adaptive Chaotic Gray Wolf Optimizer-Based Optimization of Decentralized AGC and Power Dispatching Controllers for Integrated Energy System with Heterogeneous Power Sources

    Zhongwen Li, Ningning Bai, Zhi** Cheng in Journal of Electrical Engineering & Techno… (2024)

  15. Article

    Open Access

    An alternative fully human anti-BCMA CAR-T shows response for relapsed or refractory multiple myeloma with anti-BCMA CAR-T exposures previously

    Chimeric antigen receptor T (CAR-T) cells therapy has made remarkable progress in relapsed/refractory multiple myeloma (R/R MM) treatment. Unfortunately, patients still eventually experience disease progressio...

    Qingming Wang, Runhong Wei, Shufang Guo, Chao Min, **ong Zhong in Cancer Gene Therapy (2024)

  16. Article

    Open Access

    An anti-CRISPR that represses its own transcription while blocking Cas9-target DNA binding

    AcrIIA15 is an anti-CRISPR (Acr) protein that inhibits Staphylococcus aureus Cas9 (SaCas9). Although previous studies suggested it has dual functions, the structural and biochemical basis for its two activities r...

    **eshuting Deng, Wei Sun, Xueyan Li, Jiuyu Wang, Zhi Cheng in Nature Communications (2024)

  17. Article

    Open Access

    Nonexistence of positive solutions for the weighted higher-order elliptic system with Navier boundary condition

    We establish a Liouville-type theorem for a weighted higher-order elliptic system in a wider exponent region described via a critical curve. We first establish a Liouville-type theorem to the involved integral...

    Weiwei Zhao, **aoling Shao, Changhui Hu, Zhiyu Cheng in Boundary Value Problems (2024)

  18. Article

    Open Access

    Residential mobility restrictions and adverse mental health outcomes during the COVID-19 pandemic in the UK

    During the COVID-19 pandemic, several governments tried to contain the spread of SARS-CoV-2, the virus that causes COVID-19, with lockdowns that prohibited leaving one’s residence unless carrying out a few ess...

    Ho Fai Chan, Zhiming Cheng, Silvia Mendolia, Alfredo R. Paloyo in Scientific Reports (2024)

  19. Article

    Open Access

    N6-methyladenosine modification positively regulate Japanese encephalitis virus replication

    N6-methyladenosine (m6A) is present in diverse viral RNA and plays important regulatory roles in virus replication and host antiviral innate immunity. However, the role of m6A in regulating JEV replication has...

    Min Yao, Zhirong Cheng, Xueyun Li, Yuexiang Li, Wei Ye, Hui Zhang in Virology Journal (2024)

  20. Article

    Open Access

    Interaction between diabetes and body mass index on severe headache or migraine in adults: a cross-sectional study

    Research on the effects of body mass index (BMI) on severe headache or migraine is limited and controversial. The aim of this study was to explore the association between BMI and the prevalence of migraine, wi...

    Sheng Tian, Zhijuan Cheng, Heqing Zheng, **anhui Zhong, ** Yu in BMC Geriatrics (2024)

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