33 Result(s)

Article

Alterations of conjunctival microbiota associated with orthokeratology lens wearing in myopic children

Orthokeratology (OK) lens wear increases the risk of bacterial infection, but little is known about the microbiota of the conjunctival sac in myopic children wearing OK lenses. This study aimed to investigate ...

Ju Zhang, **uhai Lu, Zhiwei Cheng, Dulei Zou, Weiyun Shi, Ting Wang in BMC Microbiology (2023)

Article

DNA methylation-activated full-length EMX1 facilitates metastasis through EMX1-EGFR-ERK axis in hepatocellular carcinoma

Altered DNA methylation is a crucial epigenetic event in hepatocellular carcinoma (HCC) development and progression. Through methylation-transcriptomic analysis, we identified a set of sixty potential DNA meth...

Dong-sheng Wen, Li-chang Huang, **ao-yun Bu, Min-ke He… in Cell Death & Disease (2023)

Article

Lactoferrin deficiency during lactation increases the risk of depressive-like behavior in adult mice

Lactoferrin is an active protein in breast milk that plays an important role in the growth and development of infants and is implicated as a neuroprotective agent. The incidence of depression is currently incr...

Wenli Wang, Zhimei Cheng, **ong Wang, Qin An, Kunlun Huang, Yun** Dai… in BMC Biology (2023)

Article

Correction: Sirt1 coordinates with ERα to regulate autophagy and adiposity

Zhipeng Tao, Limin Shi, Jane Parke, Louise Zheng, Wei Gu… in Cell Death Discovery (2023)

Article

Pericytes augment glioblastoma cell resistance to temozolomide through CCL5-CCR5 paracrine signaling

Glioblastoma (GBM) is a prevalent and highly lethal form of glioma, with rapid tumor progression and frequent recurrence. Excessive outgrowth of pericytes in GBM governs the ecology of the perivascular niche, ...

**ao-Ning Zhang, Kai-Di Yang, Cong Chen, Zhi-Cheng He, Qiang-Hu Wang… in Cell Research (2021)

Article

A cohort autopsy study defines COVID-19 systemic pathogenesis

Severe COVID-19 disease caused by SARS-CoV-2 is frequently accompanied by dysfunction of the lungs and extrapulmonary organs. However, the organotropism of SARS-CoV-2 and the port of virus entry for systemic d...

**ao-Hong Yao, Tao Luo, Yu Shi, Zhi-Cheng He, Rui Tang, Pei-Pei Zhang… in Cell Research (2021)

Article

Sirt1 coordinates with ERα to regulate autophagy and adiposity

Sex difference in adiposity has long been recognized but the mechanism remains incompletely understood. Previous studies suggested that adiposity was regulated by autophagy in response to energy status change....

Zhipeng Tao, Limin Shi, Jane Parke, Louise Zheng, Wei Gu… in Cell Death Discovery (2021)

Article

Long non-coding RNA CASC9 promotes gefitinib resistance in NSCLC by epigenetic repression of DUSP1

Resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), such as gefitinib, has greatly affected clinical outcomes in non-small cell lung cancer (NSCLC) patients. The long noncodi...

Zhenyao Chen, Qinnan Chen, Zhixiang Cheng, **gyao Gu, Wenyan Feng… in Cell Death & Disease (2020)

Article

LEF1-AS1 accelerates tumorigenesis in glioma by sponging miR-489-3p to enhance HIGD1A

Long non-coding (lncRNA) lymphoid enhancer-binding factor 1 antisense RNA 1 (LEF1-AS1) has been validated to be implicated in manifold cancers, whereas its function in glioma has not been understood thoroughly...

Zhihua Cheng, Guangyu Wang, Weiyi Zhu, Cong Luo, Zhilin Guo in Cell Death & Disease (2020)

Article

Pathological evidence for residual SARS-CoV-2 in pulmonary tissues of a ready-for-discharge patient

**ao-Hong Yao, Zhi-Cheng He, Ting-Yuan Li, Hua-Rong Zhang, Yan Wang… in Cell Research (2020)

Article

Correction: miR-1260b, mediated by YY1, activates KIT signaling by targeting SOCS6 to regulate cell proliferation and apoptosis in NSCLC

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Yang **a, Ke Wei, Feng-Ming Yang, Liu-Qing Hu, Chun-Feng Pan… in Cell Death & Disease (2020)

Article

The comprehensive detection of miRNA, lncRNA, and circRNA in regulation of mouse melanocyte and skin development

Pigmentation development, is a complex process regulated by many transcription factors during development. With the development of the RNA sequencing (RNA-seq), non-coding RNAs, such as miRNAs, lncRNAs, and ci...

Zhiwei Zhu, Yueyue Ma, Yuan Li, Pengfei Li, Zhixue Cheng, Huifeng Li… in Biological Research (2020)

Article

Correction to: Comparative proteomic analysis of Tibetan pig spermatozoa at high and low altitudes

Following publication of the original article [1], the authors reported an error in one of the authors’ names. In this Correction the incorrect and correct author name are shown. The original publication of th...

Yanling Zhao, **aoli Lu, Zhipeng Cheng, Mengfang Tian, Yangzong Qiangba… in BMC Genomics (2019)

Article

Comparative proteomic analysis of Tibetan pig spermatozoa at high and low altitudes

To illuminate the mechanisms underlying the high-altitude tolerance of Tibetan pig spermatozoa, proteomes of spermatozoa from Tibetan pigs raised in high and low altitudes were compared using a tandem mass tag...

Yanling Zhao, **aoli Lu, Zhipeng Cheng, Mengfang Tian, Yangzong Qiangba… in BMC Genomics (2019)

Article

Applying an innovative biodegradable self-assembly nanomicelles to deliver α-mangostin for improving anti-melanoma activity

α-Mangostin (αM), a traditional natural product with promising application of treating a series of diseases, was limited use in clinical due to its hydrophobicity. Herein, MPEG-PCL nanomicelles were used to em...

Shu** Yang, **ang Gao, Yihong He, Yuzhu Hu, Bocheng Xu… in Cell Death & Disease (2019)

Article

miR-1260b, mediated by YY1, activates KIT signaling by targeting SOCS6 to regulate cell proliferation and apoptosis in NSCLC

Non-small cell lung cancer (NSCLC) is one of the most common aggressive malignancies. miRNAs have been identified as important biomarkers and regulators of NSCLC. However, the functional contributions of miR-1...

Yang **a, Ke Wei, Feng-Ming Yang, Liu-Qing Hu, Chun-Feng Pan… in Cell Death & Disease (2019)

Article

VDAC2 interacts with PFKP to regulate glucose metabolism and phenotypic reprogramming of glioma stem cells

Plastic phenotype convention between glioma stem cells (GSCs) and non-stem tumor cells (NSTCs) significantly fuels glioblastoma heterogeneity that causes therapeutic failure. Recent progressions indicate that ...

Kai Zhou, Yue-Liang Yao, Zhi-Cheng He, Cong Chen, **ao-Ning Zhang… in Cell Death & Disease (2018)

Article

Genome-wide transcriptome analysis and identification of benzothiadiazole-induced genes and pathways potentially associated with defense response in banana

Bananas (Musa spp.) are the most important fruit crops worldwide due to their high nutrition value. Fusarium wilt of banana, caused by fungal pathogen Fusarium oxysporum f. sp. cubense tropical race 4 (Foc 4), is...

Zhihao Cheng, **ang Yu, Shuxia Li, Qiong Wu in BMC Genomics (2018)

Article

APP upregulation contributes to retinal ganglion cell degeneration via JNK3

Axonal injury is a common feature of central nervous system insults. Upregulation of amyloid precursor protein (APP) is observed following central nervous system neurotrauma and is regarded as a marker of cent...

Chao Liu, Cheng-Wu Zhang, Yi Zhou, Wan Qing Wong… in Cell Death & Differentiation (2018)

Article

Tamoxifen enhances stemness and promotes metastasis of ERα36⁺ breast cancer by upregulating ALDH1A1 in cancer cells

The 66 kDa estrogen receptor alpha (ERα66) is the main molecular target for endocrine therapy such as tamoxifen treatment. However, many patients develop resistance with unclear mechanisms. In a large cohort s...

Qiang Wang, Jun Jiang, Guoguang Ying, **ao-Qing **e, **a Zhang, Wei Xu… in Cell Research (2018)