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Article
Genome-wide in situ exon capture for selective resequencing
Increasingly powerful sequencing technologies are ushering in an era of personal genome sequences and raising the possibility of using such information to guide medical decisions. Genome resequencing also prom...
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Article
Open AccessBoosting with stumps for predicting transcription start sites
Promoter prediction is a difficult but important problem in gene finding, and it is critical for elucidating the regulation of gene expression. We introduce a new promoter prediction program, CoreBoost, which ...
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Article
Open AccessGenome-wide promoter extraction and analysis in human, mouse, and rat
Large-scale and high-throughput genomics research needs reliable and comprehensive genome-wide promoter annotation resources. We have conducted a systematic investigation on how to improve mammalian promoter p...
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Article
Computational comparison of two mouse draft genomes and the human golden path
The availability of both mouse and human draft genomes has marked the beginning of a new era of comparative mammalian genomics. The two available mouse genome assemblies, from the public mouse genome sequencin...