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  1. Article

    Open Access

    Estimating developmental states of tumors and normal tissues using a linear time-ordered model

    Tumor cells are considered to have an aberrant cell state, and some evidence indicates different development states appearing in the tumorigenesis. Embryonic development and stem cell differentiation are order...

    Bo Zhang, Beibei Chen, Tao Wu, Zhenyu Xuan, **aopeng Zhu in BMC Bioinformatics (2011)

  2. Article

    Open Access

    Using quality scores and longer reads improves accuracy of Solexa read map**

    Second-generation sequencing has the potential to revolutionize genomics and impact all areas of biomedical science. New technologies will make re-sequencing widely available for such applications as identifyi...

    Andrew D Smith, Zhenyu Xuan, Michael Q Zhang in BMC Bioinformatics (2008)