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Article
Open AccessEstimating developmental states of tumors and normal tissues using a linear time-ordered model
Tumor cells are considered to have an aberrant cell state, and some evidence indicates different development states appearing in the tumorigenesis. Embryonic development and stem cell differentiation are order...
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Article
Open AccessUsing quality scores and longer reads improves accuracy of Solexa read map**
Second-generation sequencing has the potential to revolutionize genomics and impact all areas of biomedical science. New technologies will make re-sequencing widely available for such applications as identifyi...