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4,760 Result(s)
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Chapter
Effect of Bombyx 4K-PTTH and Bovine Insulin on Testis Development of Indian Silkworm, Philosamia Cynthia Ricini
Recent studies have shown that Bombyx adult brain contains two types of PTTHs with different molecular weights, 4K-PTTH and 22K-PTTH. The 4K-PTTH is composed of three heterogeneous molecular species, 4K-PTTH-I...
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The Effects of High and Low Chromium Yeast Supplementation on Glucose Metabolism of Noninsulin Dependent Diabetic Patients
Chromium in the trivalent state is an essential element required for normal carbohydrate and lipid metabolism; in the form of hexavalent compounds it is a carcinogen. Chromium deficient animals display impaire...
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Numerical analysis of electromagnetic hyperthermia of the human thorax
A finite-element model is developed to analyse the feasibility of the treatment of a deep-seated thoracic tumour by hyperthermia with an annular phased array system. Owing to the presence of hot spots in the c...
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Potential-dependent action ofAnemonia sulcata toxins III and IV on sodium channels in crayfish giant axons
Effects of toxins III and IV (ATX III and IV) from the sea anemoneAnemonia sulcata on the Na current of crayfish giant axons were studied. Both toxins slowed the inactivation of Na channels, producing a maintaine...
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Pinacidil activates the ATP-sensitive K+ channel in inside-out and cell-attached patch membranes of guinea-pig ventricular myocytes
Patch-clamp techniques were used to study the effects of pinacidil on the adenosine-5′-triphosphate (ATP)-sensitive K+ channel current in guinea-pig ventricular myocytes. In inside-out patches, the ATP-sensitive ...
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The interactions of 1,4-dihydropyridines bearing a 2-(2-aminoethylthio)methyl substituent at voltage-dependent Ca+ channels of smooth muscle, cardiac muscle and neuronal tissues
The Ca2+ channel antagonistic potencies of tiamdipine [2-(2-aminoethylthio)methyl-3-carboethoxy-5-carbomethoxy-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine] and nifedipine [2,6-dimethyl-3,5-dicarbomethoxy-4-(2n...
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Stage-specific gametocytocidal effect in vitro of the antimalaria drug qinghaosu onPlasmodium falciparum
Qinghaosu, an anti-malaria drug, has been found to kill not only asexual blood stages but also the early stages of gametocytes ofPlasmodium falciparum. The effect of qinghaosu in vitro depends on the concentratio...
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PDGF and the Small Inducible Gene (SIG) Family: Roles in the Inflammatory Response
Inflammation and tissue repair involve a series of highly regulated and coordinated reactions that are beginning to be recognized and understood. Molecules ordinarily within intracellular compartments such as ...
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Article
Stress protein synthesis by crayfish CNS tissue in vitro
Some crustacean axons remain functional for months after injury. This unusual property may require stress proteins synthesized by those neurons or provided to them by glial cells. To begin to explore this hypo...
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Distribution of synapses on an intracellularly labeled small pyramidal neuron in the cat motor cortex
The morphological characteristics and distribution of synapses on a small pyramidal neuron in layer III of the cat motor cortex have been studied by combining intracellular HRP staining and electron microscopi...
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Article
Dietary retinol: prevention or promotion of carcinogenesis in humans?
A number of epidemiologic studies have found that ‘vitamin A’ is associated with a reduced risk for human cancers. Dietary vitamin A indices reflect intake of several compounds in the diet including retinol an...
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Aromatic aldehydes and aromatic ketones open ATP-sensitive K+ channels in guinea-pig ventricular myocytes
Patch-clamp techniques were used to study the effects of three carbonyl compounds, 3,4-dihydroxy-benzaldehyde, 2,3-dihydroxybenzaldehyde, and 2,4-dihydroxy-acetophenone, on the adenosine-5′-triphosphate(ATP)-s...
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Oocyte selection: a new model for the maternal-age dependence of Down syndrome
Previously proposed mechanisms for Down syndrome (trisomy 21) have generally invoked a progressive increase in meiotic nondisjunction to explain maternal-age dependence, but models of this sort have failed to ...
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Article
Time trend and age-period-cohort effects on incidence of esophageal cancer in Connecticut, 1935–89
The purpose of this study was to examine the incidence pattern of esophageal eancer in Connecticut (USA) during the past decades, and to identify components of birth cohort, period, and age as determinants of ...
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Stress protein synthesis and accumulation after traumatic injury of crayfish CNS
By several days after a crush injury of crayfish CNS, the wound site heals. Changes in protein synthesis and accumulation occur at the lesion site and nearby. During the first few hours, synthesis of 35, 70, 9...
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Article
Incidence trends for cancers of the breast, ovary, and corpus uteri in urban Shanghai, 1972–89
Incidence data from the Shanghai (People's Republic of China) Cancer Registry were used to assess the temporal trends of three major female cancers during 1972–89. Rates for cancers of the breast, corpus uteri...
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A cohort study of smoking, alcohol consumption, and dietary factors for pancreatic cancer (United States)
Risk factors for pancreatic cancer were evaluated in a cohort study of 17,633 White men in the United States who responded to a mailed questionnaire in 1966 and were followed-up through 1986 for mortality. Cig...
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Long-Lasting Modulation of Synaptic Transmission by Metabotropic Glutamate Receptors
Studies of the functional roles for metabotropic glutamate receptors (mGluRs) in the central nervous system have rapidly developed over the past two years. mGluR agonists have a diverse range of electrophysiol...
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The Effect of Partial Hepatectomy on Blood Purine Levels in Rats and Patients
Purine metabolism is a key metabolic process after partial hepatectomy in the synthesis of DNA and RNA, and in the energy metabolism for hepatic regeneration1. However it is not evaluated in clinical situations d...
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Immunological Tolerance by Antigen-Induced Apoptosis of Mature T Lymphocytes
Although the immune system has evolved to mount defensive lymphocyte activation responses to pathogens, it has long been known that antigen can specifically abrogate an immune response.1 This form of acquired imm...