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Article
Androgenetic haploid embryonic stem cells produce live transgenic mice
Mouse androgenetic haploid embryonic stem cell lines can be established by transferring sperm into an enucleated oocyte; the cells maintain haploidy and stable growth over 30 passages, express pluripotent mark...
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Article
Open AccessPreparation of Few-Layer Bismuth Selenide by Liquid-Phase-Exfoliation and Its Optical Absorption Properties
Bismuth selenide (Bi2Se3), a new topological insulator, has attracted much attention in recent years owing to its relatively simple band structure and large bulk band gap. Compared to bulk, few-layer Bi2Se3 is re...
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Article
Unique features of the m6A methylome in Arabidopsis thaliana
Recent discoveries of reversible N6-methyladenosine (m6A) methylation on messenger RNA (mRNA) and map** of m6A methylomes in mammals and yeast have revealed potential regulatory functions of this RNA modificati...
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Open AccessPrevalence and molecular characterizations of enterovirus D68 among children with acute respiratory infection in China between 2012 and 2014
EV-D68 is associated with respiratory tract infections (RTIs). Since its first isolation, EV-D68 has been detected sporadically. However, the US and Canada have experienced outbreaks of EV-D68 infections betwe...
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Open AccessAn integrated multi-electrode-optrode array for in vitro optogenetics
Modulation of a group of cells or tissue needs to be very precise in order to exercise effective control over the cell population under investigation. Optogenetic tools have already demonstrated to be of great...
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Article
Open AccessNotch signaling indirectly promotes chondrocyte hypertrophy via regulation of BMP signaling and cell cycle arrest
Cell cycle regulation is critical for chondrocyte differentiation and hypertrophy. Recently we identified the Notch signaling pathway as an important regulator of chondrocyte proliferation and differentiation ...
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Open AccessAbundant DNA 6mA methylation during early embryogenesis of zebrafish and pig
DNA N6-methyldeoxyadenosine (6mA) is a well-known prokaryotic DNA modification that has been shown to exist and play epigenetic roles in eukaryotic DNA. Here we report that 6mA accumulates up to ∼0.1–0.2% of tota...
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Open AccessAn integrated analysis based on transcriptome and proteome reveals deastringency-related genes in CPCNA persimmon
Persimmon fruits accumulate a large amount of proanthocyanidins (PAs) during development. PAs cause a dry or puckering sensation due to its astringency. Pollination constant and non-astringent (PCNA) persimmon...
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Article
Open AccessAssembly of gold nanoparticles into aluminum nanobowl array
We mimic unique honeycomb structure as well as its functions of storing honey and pollen to assemble Au nanoparticle pattern on honeycomb-like Al nanobowl array by utilizing solid state dewetting process. Patt...
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Article
Open AccessHuman Mesenchymal Stromal Cell Sheet Enhances Allograft Repair in a Mouse Model
To determine whether cell sheets generated with long-term passaged (P10) aging human mesenchymal stromal cells (MSCs) could be used for bone tissue regeneration as tissue engineered periosteum in a femoral all...
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Open AccessThe Cdh5-CreERT2 transgene causes conditional Shb gene deletion in hematopoietic cells with consequences for immune cell responses to tumors
The tamoxifen-responsive conditional Cdh5-CreERT2 is commonly used for endothelial cell specific conditional deletion of loxP-flanked gene sequences. To address the role of endothelial cell Shb gene for B16F10 me...
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Open AccessMetabolomic Profiles of Bovine Mammary Epithelial Cells Stimulated by Lipopolysaccharide
Bovine mammary epithelial cells (bMECs) are the main cells of the dairy cow mammary gland. In addition to their role in milk production, they are effector cells of mammary immunity. However, there is little in...
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Article
Open AccessLarge-area epitaxial growth of curvature-stabilized ABC trilayer graphene
The properties of van der Waals (vdW) materials often vary dramatically with the atomic stacking order between layers, but this order can be difficult to control. Trilayer graphene (TLG) stacks in either a sem...
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Article
Open AccessSimultaneous enhanced efficiency and thermal stability in organic solar cells from a polymer acceptor additive
The thermal stability of organic solar cells is critical for practical applications of this emerging technology. Thus, effective approaches and strategies need to be found to alleviate their inherent thermal i...
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Article
Open AccessVitamin A supplement after neonatal Streptococcus pneumoniae pneumonia inhibits the progression of experimental asthma by altering CD4+T cell subsets
Studies demonstrated that pneumonia can decrease vitamin A productions and vitamin A reduction/deficiency may promote asthma development. Our previous study showed that neonatal Streptococcus pneumoniae (S. pneum...
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Open AccessReaction mechanism and kinetics for CO2 reduction on nickel single atom catalysts from quantum mechanics
Experiments have shown that graphene-supported Ni-single atom catalysts (Ni-SACs) provide a promising strategy for the electrochemical reduction of CO2 to CO, but the nature of the Ni sites (Ni-N2C2, Ni-N3C1, Ni-...
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Open AccessApplication of unmanned aerial vehicle (UAV) thermal infrared remote sensing to identify coal fires in the Huojitu coal mine in Shenmu city, China
China is a major coal-producing country that consumes large amounts of coal every year. Due to the existence of many small coal kilns using backward mining methods, numerous worked-out areas have been formed. ...
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Open AccessToward a mechanistic understanding of electrocatalytic nanocarbon
Electrocatalytic nanocarbon (EN) is a class of material receiving intense interest as a potential replacement for expensive, metal-based electrocatalysts for energy conversion and chemical production applicati...
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Open AccessMeta-analysis of the effects of ambient temperature and relative humidity on the risk of mumps
Many studies have shown that the relationship between ambient temperature, relative humidity and mumps has been highlighted. However, these studies showed inconsistent results. Therefore, the goal of our study...
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Open AccessEffects of modified atmosphere packaging on the postharvest quality of mulberry leaf vegetable
Fresh mulberry leaf vegetable is nutritive and becoming popular. However, available preservation technologies are deficient. In present work, the effects of two kinds of modified atmosphere packaging on postha...