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  1. Article

    Open Access

    Lung cancer surgery: innovations and future perspectives

    Nine decades ago in 1933, Evarts A. Graham performed the first successful pneumonectomy in a patient with primary pulmonary squamous cell carcinoma. The patient survived for another 30 years, which drew the cu...

    **angyang Yu, Feng Wang, Kai Ma, Zhentao Yu in Clinical Cancer Bulletin (2024)

  2. No Access

    Article

    Cachexia Versus Sarcopenia in Clinical Characteristics and Prognostic Value After Radical Gastrectomy for Gastric Cancer: A Large-Scale Prospective Study

    Sarcopenia and cachexia are two predictors of adverse clinical outcomes, but they are partly overlap**. We aimed to compare the characteristics and prognostic value of cachexia and sarcopenia in patients aft...

    Cheng-Le Zhuang PhD, Qian-Tong Dong MD, Han-** Shi PhD in Annals of Surgical Oncology (2022)

  3. No Access

    Article

    ASO Author Reflections: Do Shorter Tumor-to-Nipple Distances Compromise the Local Oncologic Safety of Nipple-Sparing Mastectomy?

    Zhen-Yu Wu MD, PhD, **g Han MD, ** Sup Eom MD, PhD in Annals of Surgical Oncology (2021)

  4. No Access

    Article

    Oncologic Safety of Nipple-Sparing Mastectomy in Patients with Breast Cancer and Tumor-to-Nipple Distance ≤ 1 cm: A Matched Cohort Study

    A short tumor-to-nipple distance (TND) is reported as a strong predictor of nipple-areola complex (NAC) involvement. Eligibility for nipple-sparing mastectomy (NSM) remains controversial, especially regarding ...

    Zhen-Yu Wu MD, PhD, Hee Jeong Kim MD, PhD in Annals of Surgical Oncology (2021)

  5. Article

    Open Access

    Cathepsin L promotes angiogenesis by regulating the CDP/Cux/VEGF-D pathway in human gastric cancer

    Increasing evidence indicates that angiogenesis plays an important role in tumor progression. The function of cathepsin L (CTSL), an endosomal proteolytic enzyme, in promoting tumor metastasis is well recogniz...

    Tao Pan, Zhijian **, Zhenjia Yu, **ongyan Wu, **nyu Chang, Zhiyuan Fan in Gastric Cancer (2020)

  6. No Access

    Article

    ASO Author Reflections: Risk of Locoregional Recurrence After Nipple-Sparing Mastectomy and Immediate Breast Reconstruction for Pure Ductal Carcinoma In Situ

    Zhen Yu Wu MD, BeomSeok Ko MD in Annals of Surgical Oncology (2020)

  7. No Access

    Article

    Recurrence Outcomes After Nipple-Sparing Mastectomy and Immediate Breast Reconstruction in Patients with Pure Ductal Carcinoma In Situ

    Nipple-sparing mastectomy (NSM) has become increasingly prevalent for patients with ductal carcinoma in situ (DCIS) requiring mastectomy. However, few data regarding recurrence outcomes after NSM are available...

    Zhen Yu Wu MD, PhD, Hee-Jeong Kim MD, PhD in Annals of Surgical Oncology (2020)

  8. Article

    Oncostatin M receptor, positively regulated by SP1, promotes gastric cancer growth and metastasis upon treatment with Oncostatin M

    Oncostatin M receptor (OSMR) is a member of the interleukin 6 (IL-6) receptor family that transduces signaling events of Oncostatin M (OSM). OSM–OSMR signaling plays a key role in inflammation and cancer progr...

    Zhenjia Yu, Zhen Li, Chenchen Wang, Tao Pan, **nyu Chang, in Gastric Cancer (2019)

  9. Article

    Comparison of the diagnostic efficacy of white light endoscopy and magnifying endoscopy with narrow band imaging for early gastric cancer: a meta-analysis

    Magnifying endoscopy with narrow band imaging (ME-NBI) is widely used in gastroscopy, especially in the diagnosis of early gastric cancer. The purpose of this meta-analysis is to compare the diagnostic effica...

    Qiang Zhang, Fei Wang, Zhen-Yu Chen, Zhen Wang, Fa-Chao Zhi, Si-De Liu in Gastric Cancer (2016)

  10. No Access

    Article

    Sarcopenia Adversely Impacts Postoperative Clinical Outcomes Following Gastrectomy in Patients with Gastric Cancer: A Prospective Study

    Sarcopenia is characterized by decreased skeletal muscle plus low muscle strength and/or physical performance. This study was performed to determine the association of sarcopenia with short-term postoperative ...

    Su-Lin Wang MD, Cheng-Le Zhuang MD, Dong-Dong Huang MD in Annals of Surgical Oncology (2016)

  11. No Access

    Article

    The flavonoid casticin enhances TRAIL-induced apoptosis of colon cancer cells through endoplasmic reticulum stress-mediated up-regulation of DR5

    The aim of this study was to explore the mechanisms by which the flavonoid casticin enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in colon cancer cells.

    Sanyuan Tang, Guang** Yuan, Zhengyang Yu in The Chinese-German Journal of Clinical Onc… (2013)

  12. No Access

    Article

    Is pT2 Subclassification Feasible to Predict Patient Outcome in Colorectal Cancer?

    This study aimed to evaluate the prognostic impact of pT2 subclassification according to the depth of muscularis propria (MP) invasion and to explore the clinicopathologic factors correlated with lymph node me...

    Lin-lin Tong MD, Peng Gao MD, Zhen-ning Wang MD, PhD in Annals of Surgical Oncology (2011)

  13. No Access

    Article

    Radiation-Induced Cellular DNA Damage Repair Response Enhances Viral Gene Therapy Efficacy in the Treatment of Malignant Pleural Mesothelioma

    Malignant pleural mesothelioma (MPM) treated with radiotherapy (RT) has incomplete responses as a result of radiation-induced tumoral stress response that repairs DNA damage. Such stress response is beneficial...

    Prasad S. Adusumilli MD, Mei-Ki Chan BS, Michael Hezel BS in Annals of Surgical Oncology (2007)