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356 Result(s)
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Article
The effect of bioC gene on ultraviolet radiation and oxidative resistance of Bacillus thuringiensis (Bacillales: Bacillaceae)
Bacillus thuringiensis (Bacillales: Bacillaceae) (Bt) has played a significant role in pest control, which is the most intensively studied, rapidly developed, and widely used insecticidal microorganism in recent ...
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Open AccessCorrection: Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis
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Article
Open AccessTranscriptome profiling of fast/glycolytic and slow/oxidative muscle fibers in aging and obesity
Aging and obesity pose significant threats to public health and are major contributors to muscle atrophy. The trends in muscle fiber types under these conditions and the transcriptional differences between dif...
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Article
Two new aromatic tenvermectins from mutant Streptomyces avermitilis HU02-06
Two new aromatic tenvermectins (TVMs), 13-oleandrosyl-oleandrosyloxy ST906 (1) and aromatic TVM B (2), were isolated from the fermentation broth of Streptomyces avermitilis HU02-06. Their structures were establis...
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Article
Reference Intervals of Serum Iodine Concentration in Chinese Pregnant Women
The study aims to establish trimester-specific reference ranges for serum iodine (SI) in Chinese pregnant women and explore its associations with maternal and infantile thyroid function. Apparently healthy pre...
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Pparα activation stimulates autophagic flux through lipid catabolism-independent route
Autophagy is a cellular process that involves the fusion of autophagosomes and lysosomes to degrade damaged proteins or organelles. Triglycerides are hydrolyzed by autophagy, releasing fatty acids for energy t...
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Open AccessCirculating tumour cells predict recurrences and survival in head and neck squamous cell carcinoma patients
Patients with head and neck squamous cell carcinoma (HNSCC) are at a high risk of develo** recurrence and secondary cancers. This study evaluates the prognostic and surveillance utilities of circulating tumo...
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Low temperature-mediated changes in soil free-living nitrogen fixation functional groups in tree species at different successional stages in subtropical forests
Late-successional trees have a relatively high growth rate at low temperature, which is important for their competitive advantage over mid-successional trees. However, we have a limited understanding of the un...
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Open AccessPitfalls in forest carbon sink projection
Global forests are increasingly crucial for achieving net-zero carbon emissions, with a quarter of the mitigation efforts under the Paris Climate Agreement directed towards forests. In China, forests currently...
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Canonical ammonia oxidizers and comammox Clade A play active roles in nitrification in a black soil at different pH and ammonium concentrations
The discovery of complete ammonia oxidizers (comammox) challenged our cognition of the nitrification process. Ammonia oxidizing archaea (AOA), ammonia oxidizing bacteria (AOB) and comammox can carry out soil a...
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Open AccessBiomimetic peroxidase MOF-Fe promotes bone defect repair by inhibiting TfR2 and activating the BMP2 pathway
Large bone defects pose a clinical treatment challenge; inhibiting transferrin receptor 2 (TfR2), which is involved in iron metabolism, can promote osteogenesis. Iron-based metal-organic frameworks (MOF-Fe) pa...
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Open AccessscGAL: unmask tumor clonal substructure by jointly analyzing independent single-cell copy number and scRNA-seq data
Accurately deciphering clonal copy number substructure can provide insights into the evolutionary mechanism of cancer, and clustering single-cell copy number profiles has become an effective means to unmask in...
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Open AccessDraft Genome Sequence of Candida saopaulonensis from a Very Premature Infant with Sepsis
The rare fungus Candida saopaulonensis has never been reported to be associated with human infection. We report the draft genome sequence of the first clinical isolate of C. saopaulonensis, which was isolated fro...
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Open AccessEffect of stress urinary incontinence on vaginal microbial communities
Postpartum women often experience stress urinary incontinence (SUI) and vaginal microbial dysbiosis, which seriously affect women’s physical and mental health. Understanding the relationship between SUI and va...
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Article
Kinesin-7 CENP-E mediates chromosome alignment and spindle assembly checkpoint in meiosis I
In eukaryotes, meiosis is the genetic basis for sexual reproduction, which is important for chromosome stability and species evolution. The defects in meiosis usually lead to chromosome aneuploidy, reduced gam...
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Open AccessDeep neural network-estimated age using optical coherence tomography predicts mortality
The concept of biological age has emerged as a measurement that reflects physiological and functional decline with ageing. Here we aimed to develop a deep neural network (DNN) model that predicts biological ag...
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Identification of GmPT proteins and investigation of their expressions in response to abiotic stress in soybean
Investigation the expression patterns of GmPT genes in response to various abiotic stresses and overexpression of GmPT11 in soybean hairy roots and Arabidopsis exhibited hypersensitivity to salt stress.
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Identification of the domestication gene GmCYP82C4 underlying the major quantitative trait locus for the seed weight in soybean
A major quantitative trait locus (QTL) for the hundred-seed weight (HSW) was identified and confirmed in the two distinct soybean populations, and the target gene GmCYP82C4 underlying this locus was identified th...
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Open AccessBioinformatic analysis and experimental validation of cuproptosis-related LncRNA as a novel biomarker for prognosis and immunotherapy of oral squamous cell carcinoma
The novel form of regulatory cell death, cuproptosis, is characterized by proteotoxicity, which ultimately leads to cell death. Its targeting has emerged as a promising therapeutic approach for oral squamous c...
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Open AccessHigh-resolution structure and biochemical properties of the LH1–RC photocomplex from the model purple sulfur bacterium, Allochromatium vinosum
The mesophilic purple sulfur phototrophic bacterium Allochromatium (Alc.) vinosum (bacterial family Chromatiaceae) has been a favored model for studies of bacterial photosynthesis and sulfur metabolism, and its c...